IL-6 as a keystone cytokine in health and disease.

Articles citing IL-6 as a keystone cytokine in health and disease.

Title / Author	Year
A meta-analysis of blood cytokine network alterations in psychiatric patients: comparisons between schizophrenia, bipolar disorder and depression DR Goldsmith, MH Rapaport, BJ Miller Molecular psychiatry 21 (12), 1696-1709	2016
Targeting the IL-6/JAK/STAT3 signalling axis in cancer DE Johnson, RA O'Keefe, JR Grandis Nature Reviews Clinical Oncology 15 (4), 234	2018
Tet2 is required to resolve inflammation by recruiting Hdac2 to specifically repress IL-6 Q Zhang, K Zhao, Q Shen, Y Han, Y Gu, X Li, D Zhao, Y Liu, C Wang, ... Nature 525 (7569), 389-393	2015
Monocyte-derived IL-1 and IL-6 are differentially required for cytokine-release syndrome and neurotoxicity due to CAR T cells M Norelli, B Camisa, G Barbiera, L Falcone, A Purevdorj, M Genua, ... Nature medicine 24 (6), 739-748	2018
IL-6 pathway in the liver: From physiopathology to therapy D Schmidt-Arras, S Rose-John Journal of hepatology 64 (6), 1403-1415	2016
The cytokine release syndrome (CRS) of severe COVID-19 and Interleukin-6 receptor (IL-6R) antagonist Tocilizumab may be the key to reduce the mortality C Zhang, Z Wu, JW Li, H Zhao, GQ Wang International journal of antimicrobial agents, 105954	2020
Cytokine release syndrome A Shimabukuro-Vornhagen, P Gödel, M Subklewe, HJ Stemmler, ... Journal for immunotherapy of cancer 6 (1), 56	2018
Mendelian randomization in cardiometabolic disease: challenges in evaluating causality MV Holmes, M Ala-Korpela, GD Smith Nature Reviews Cardiology 14 (10), 577-590	2017
Stress-sensing mechanisms and the physiological roles of the Keap1–Nrf2 system during cellular stress T Suzuki, M Yamamoto Journal of Biological Chemistry 292 (41), 16817-16824	2017
Liver—guardian, modifier and target of sepsis P Strnad, F Tacke, A Koch, C Trautwein Nature reviews Gastroenterology & hepatology 14 (1), 55	2017
STAT3 signaling in immunity EJ Hillmer, H Zhang, HS Li, SS Watowich Cytokine & growth factor reviews 31, 1-15	2016
Dental pulp defence and repair mechanisms in dental caries JC Farges, B Alliot-Licht, E Renard, M Ducret, A Gaudin, AJ Smith, ... Mediators of inflammation 2015	2015
Recent insights into targeting the IL-6 cytokine family in inflammatory diseases and cancer SA Jones, BJ Jenkins Nature Reviews Immunology 18 (12), 773-789	2018
An immune clock of human pregnancy N Aghaeepour, EA Ganio, D Mcilwain, AS Tsai, M Tingle, S Van Gassen, ... Science immunology 2 (15)	2017
Interleukin-6: designing specific therapeutics for a complex cytokine C Garbers, S Heink, T Korn, S Rose-John Nature Reviews Drug Discovery 17 (6), 395-412	2018
STAT3 in the systemic inflammation of cancer cachexia TA Zimmers, ML Fishel, A Bonetto Seminars in cell & developmental biology 54, 28-41	2016
Assessment of Tocilizumab (Anti–Interleukin‐6 Receptor Monoclonal) as a Potential Treatment for Chronic Antibody‐Mediated Rejection and Transplant Glomerulopathy in HLA‐Sensitized Renal Allograft Recipients J Choi, O Aubert, A Vo, A Loupy, M Haas, D Puliyanda, I Kim, S Louie, ... American Journal of Transplantation 17 (9), 2381-2389	2017
The role of IL-6 in host defence against infections: immunobiology and clinical implications S Rose-John, K Winthrop, L Calabrese Nature Reviews Rheumatology 13 (7), 399	2017
Novel targeted therapies for inflammatory bowel disease M Coskun, S Vermeire, OH Nielsen Trends in pharmacological sciences 38 (2), 127-142	2017
Deletion of interleukin-6 attenuates pressure overload-induced left ventricular hypertrophy and dysfunction L Zhao, G Cheng, R Jin, MR Afzal, A Samanta, YT Xuan, M Girgis, ... Circulation research 118 (12), 1918-1929	2016

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