Ernst Lengyel
Ernst Lengyel
Professor of Gynecologic Oncology, University of Chicago
Verified email at - Homepage
Cited by
Cited by
The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2
SM Park, AB Gaur, E Lengyel, ME Peter
Genes & development 22 (7), 894-907, 2008
Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth
KM Nieman, HA Kenny, CV Penicka, A Ladanyi, R Buell-Gutbrod, ...
Nature medicine 17 (11), 1498-1503, 2011
Ovarian cancer development and metastasis
E Lengyel
The American journal of pathology 177 (3), 1053-1064, 2010
Rethinking ovarian cancer: recommendations for improving outcomes
S Vaughan, JI Coward, RC Bast, A Berchuck, JS Berek, JD Brenton, ...
Nature Reviews Cancer 11 (10), 719-725, 2011
Whole–genome characterization of chemoresistant ovarian cancer
AM Patch, EL Christie, D Etemadmoghadam, DW Garsed, J George, ...
Nature 521 (7553), 489-494, 2015
Rethinking ovarian cancer II: reducing mortality from high-grade serous ovarian cancer
DD Bowtell, S Böhm, AA Ahmed, PJ Aspuria, RC Bast, V Beral, JS Berek, ...
Nature reviews Cancer 15 (11), 668-679, 2015
Adipose tissue and adipocytes support tumorigenesis and metastasis
KM Nieman, IL Romero, B Van Houten, E Lengyel
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2013
Let-7 expression defines two differentiation stages of cancer
S Shell, SM Park, AR Radjabi, R Schickel, EO Kistner, DA Jewell, C Feig, ...
Proceedings of the National Academy of Sciences 104 (27), 11400-11405, 2007
Rac1 in human breast cancer: overexpression, mutation analysis, and characterization of a new isoform, Rac1b
A Schnelzer, D Prechtel, U Knaus, K Dehne, M Gerhard, H Graeff, ...
Oncogene 19 (26), 3013-3020, 2000
Increased expression of matrix metalloproteinases (MMP)-2, MMP-9, and the urokinase-type plasminogen activator is associated with progression from benign to advanced ovarian cancer
B Schmalfeldt, D Prechtel, K Härting, K Späthe, S Rutke, E Konik, ...
Clinical Cancer Research 7 (8), 2396-2404, 2001
Stimulation of 92-kDa Gelatinase B Promoter Activity by ras Is Mitogen-activated Protein Kinase Kinase 1-independent and Requires Multiple Transcription Factor Binding Sites …
R Gum, E Lengyel, J Juarez, JH Chen, H Sato, M Seiki, D Boyd
Journal of Biological Chemistry 271 (18), 10672-10680, 1996
CD95 promotes tumour growth
L Chen, SM Park, AV Tumanov, A Hau, K Sawada, C Feig, JR Turner, ...
Nature 465 (7297), 492-496, 2010
Loss of E-cadherin promotes ovarian cancer metastasis via α5-integrin, which is a therapeutic target
K Sawada, AK Mitra, AR Radjabi, V Bhaskar, EO Kistner, M Tretiakova, ...
Cancer research 68 (7), 2329-2339, 2008
The initial steps of ovarian cancer cell metastasis are mediated by MMP-2 cleavage of vitronectin and fibronectin
HA Kenny, S Kaur, LM Coussens, E Lengyel
The Journal of clinical investigation 118 (4), 1367-1379, 2008
m 6 A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer
J Liu, MA Eckert, BT Harada, SM Liu, Z Lu, K Yu, SM Tienda, ...
Nature cell biology 20 (9), 1074-1083, 2018
MicroRNAs reprogram normal fibroblasts into cancer-associated fibroblasts in ovarian cancer
AK Mitra, M Zillhardt, Y Hua, P Tiwari, AE Murmann, ME Peter, E Lengyel
Cancer discovery 2 (12), 1100-1108, 2012
Dosimetric predictors of acute hematologic toxicity in cervical cancer patients treated with concurrent cisplatin and intensity-modulated pelvic radiotherapy
LK Mell, JD Kochanski, JC Roeske, JJ Haslam, N Mehta, SD Yamada, ...
International Journal of Radiation Oncology* Biology* Physics 66 (5), 1356-1365, 2006
C‐Met overexpression in node‐positive breast cancer identifies patients with poor clinical outcome independent of Her2/neu
E Lengyel, D Prechtel, JH Resau, K Gauger, A Welk, K Lindemann, ...
International journal of cancer 113 (4), 678-682, 2005
Let-7 prevents early cancer progression by suppressing expression of the embryonic gene HMGA2
SM Park, S Shell, AR Radjabi, R Schickel, C Feig, B Boyerinas, ...
Cell cycle 6 (21), 2585-2590, 2007
c-Met overexpression is a prognostic factor in ovarian cancer and an effective target for inhibition of peritoneal dissemination and invasion
K Sawada, AR Radjabi, N Shinomiya, E Kistner, H Kenny, AR Becker, ...
Cancer research 67 (4), 1670-1679, 2007
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