Multiple sulfatase deficiency is caused by mutations in the gene encoding the human Cα-formylglycine generating enzyme T Dierks, B Schmidt, LV Borissenko, J Peng, A Preusser, M Mariappan, ... Cell 113 (4), 435-444, 2003 | 446 | 2003 |
A ribosome-associating factor chaperones tail-anchored membrane proteins M Mariappan, X Li, S Stefanovic, A Sharma, A Mateja, RJ Keenan, ... Nature 466 (7310), 1120-1124, 2010 | 313 | 2010 |
Protein targeting and degradation are coupled for elimination of mislocalized proteins T Hessa, A Sharma, M Mariappan, HD Eshleman, E Gutierrez, RS Hegde Nature 475 (7356), 394-397, 2011 | 290 | 2011 |
Molecular basis for multiple sulfatase deficiency and mechanism for formylglycine generation of the human formylglycine-generating enzyme T Dierks, A Dickmanns, A Preusser-Kunze, B Schmidt, M Mariappan, ... Cell 121 (4), 541-552, 2005 | 216 | 2005 |
The structural basis of tail-anchored membrane protein recognition by Get3 A Mateja, A Szlachcic, ME Downing, M Dobosz, M Mariappan, RS Hegde, ... Nature 461 (7262), 361-366, 2009 | 198 | 2009 |
The mechanism of membrane-associated steps in tail-anchored protein insertion M Mariappan, A Mateja, M Dobosz, E Bove, RS Hegde, RJ Keenan nature 477 (7362), 61-66, 2011 | 177 | 2011 |
A functional link between the co-translational protein translocation pathway and the UPR. MM Plumb R, Zhang ZR, Appathurai S eLIFE, 2015 | 110 | 2015 |
In vitro dissection of protein translocation into the mammalian endoplasmic reticulum A Sharma, M Mariappan, S Appathurai, RS Hegde Protein Secretion: Methods and Protocols, 339-363, 2010 | 92 | 2010 |
Molecular characterization of the human Cα-formylglycine-generating enzyme A Preusser-Kunze, M Mariappan, B Schmidt, SL Gande, K Mutenda, ... Journal of Biological Chemistry 280 (15), 14900-14910, 2005 | 89 | 2005 |
The Sec61 translocon limits IRE1α signaling during the unfolded protein response A Sundaram, R Plumb, S Appathurai, M Mariappan elife 6, e27187, 2017 | 66 | 2017 |
Dynamic changes in complexes of IRE1α, PERK, and ATF6α during endoplasmic reticulum stress A Sundaram, S Appathurai, R Plumb, M Mariappan Molecular biology of the cell 29 (11), 1376-1388, 2018 | 59 | 2018 |
ERp44 mediates a thiol-independent retention of formylglycine-generating enzyme in the endoplasmic reticulum M Mariappan, K Radhakrishnan, T Dierks, B Schmidt, K von Figura Journal of biological chemistry 283 (10), 6375-6383, 2008 | 52 | 2008 |
Expression, localization, structural, and functional characterization of pFGE, the paralog of the Cα-formylglycine-generating enzyme M Mariappan, A Preusser-Kunze, M Balleininger, N Eiselt, B Schmidt, ... Journal of Biological Chemistry 280 (15), 15173-15179, 2005 | 43 | 2005 |
Crystal structure of human pFGE, the paralog of the Cα-formylglycine-generating enzyme A Dickmanns, B Schmidt, MG Rudolph, M Mariappan, T Dierks, ... Journal of Biological Chemistry 280 (15), 15180-15187, 2005 | 37 | 2005 |
A molecular mechanism for turning off IRE1α signaling during endoplasmic reticulum stress X Li, S Sun, S Appathurai, A Sundaram, R Plumb, M Mariappan Cell reports 33 (13), 2020 | 34 | 2020 |
Eukaryotic formylglycine‐generating enzyme catalyses a monooxygenase type of reaction J Peng, S Alam, K Radhakrishnan, M Mariappan, MG Rudolph, C May, ... The FEBS Journal 282 (17), 3262-3274, 2015 | 34 | 2015 |
The non-catalytic N-terminal extension of formylglycine-generating enzyme is required for its biological activity and retention in the endoplasmic reticulum M Mariappan, SL Gande, K Radhakrishnan, B Schmidt, T Dierks, ... Journal of biological chemistry 283 (17), 11556-11564, 2008 | 26 | 2008 |
Paralog of the formylglycine‐generating enzyme–retention in the endoplasmic reticulum by canonical and noncanonical signals SL Gande, M Mariappan, B Schmidt, TH Pringle, K von Figura, T Dierks The FEBS Journal 275 (6), 1118-1130, 2008 | 19 | 2008 |
Adaptive protein translation by the integrated stress response maintains the proliferative and migratory capacity of lung adenocarcinoma cells AE Albert, SJ Adua, WL Cai, A Arnal-Estapé, GW Cline, Z Liu, M Zhao, ... Molecular Cancer Research 17 (12), 2343-2355, 2019 | 17 | 2019 |
Deubiquitinases USP20/33 promote the biogenesis of tail-anchored membrane proteins JA Culver, M Mariappan Journal of Cell Biology 220 (5), e202004086, 2021 | 16 | 2021 |