Novel multi-target-directed ligands for Alzheimer's disease: combining cholinesterase inhibitors and 5-HT6 receptor antagonists. Design, synthesis and biological evaluation A Więckowska, M Kołaczkowski, A Bucki, J Godyń, M Marcinkowska, ... European Journal of Medicinal Chemistry 124, 63-81, 2016 | 86 | 2016 |
A microwave-assisted, propylphosphonic anhydride (T3P®) mediated one-pot Fischer indole synthesis M Desroses, K Wieckowski, M Stevens, LR Odell Tetrahedron letters 52 (34), 4417-4420, 2011 | 69 | 2011 |
Antiallodynic and antihyperalgesic activity of 3-[4-(3-trifluoromethyl-phenyl)-piperazin-1-yl]-dihydrofuran-2-one compared to pregabalin in chemotherapy-induced neuropathic … K Sałat, A Cios, E Wyska, R Sałat, S Mogilski, B Filipek, K Więckowski, ... Pharmacology Biochemistry and Behavior 122, 173-181, 2014 | 65 | 2014 |
Synthesis of new N-benzylpiperidine derivatives as cholinesterase inhibitors with β-amyloid anti-aggregation properties and beneficial effects on memory in vivo A Więckowska, K Więckowski, M Bajda, B Brus, K Sałat, P Czerwińska, ... Bioorganic & medicinal chemistry 23 (10), 2445-2457, 2015 | 61 | 2015 |
Novel multitarget-directed ligands aiming at symptoms and causes of Alzheimer’s disease A Wieckowska, T Wichur, J Godyń, A Bucki, M Marcinkowska, A Siwek, ... ACS chemical neuroscience 9 (5), 1195-1214, 2018 | 56 | 2018 |
1-Benzylpyrrolidine-3-amine-based BuChE inhibitors with anti-aggregating, antioxidant and metal-chelating properties as multifunctional agents against Alzheimer’s disease T Wichur, A Więckowska, K Więckowski, J Godyń, J Jończyk, ... European Journal of Medicinal Chemistry 187, 111916, 2020 | 46 | 2020 |
Evaluation of antinociceptive and antioxidant properties of 3-[4-(3-trifluoromethyl-phenyl)-piperazin-1-yl]-dihydrofuran-2-one in mice K Sałat, K Gawlik, J Witalis, D Pawlica-Gosiewska, B Filipek, B Solnica, ... Naunyn-schmiedeberg's Archives of Pharmacology 386, 493-505, 2013 | 39 | 2013 |
Analgesic, anticonvulsant and antioxidant activities of 3-[4-(3-trifluoromethyl-phenyl)-piperazin-1-yl]-dihydrofuran-2-one dihydrochloride in mice K Salat, A Moniczewski, R Salat, M Janaszek, B Filipek, B Malawska, ... Pharmacology Biochemistry and Behavior 101 (1), 138-147, 2012 | 38 | 2012 |
Evaluation of anxiolytic-like, anticonvulsant, antidepressant-like and antinociceptive properties of new 2-substituted 4-hydroxybutanamides with affinity for GABA transporters … K Sałat, K Kulig, J Gajda, K Więckowski, B Filipek, B Malawska Pharmacology Biochemistry and Behavior 110, 145-153, 2013 | 31 | 2013 |
Synthesis and pharmacological properties of new GABA uptake inhibitors K Sałat, A Więckowska, K Więckowski, GC Höfner, J Kamiński, ... Pharmacological Reports 64 (4), 817-833, 2012 | 30 | 2012 |
Novel 3-(1,2,3,6-Tetrahydropyridin-4-yl)-1H-indole-Based Multifunctional Ligands with Antipsychotic-Like, Mood-Modulating, and Procognitive Activity A Bucki, M Marcinkowska, J Sniecikowska, K Wieckowski, M Pawłowski, ... Journal of Medicinal Chemistry 60 (17), 7483-7501, 2017 | 29 | 2017 |
Analgesic activity of 3-mono-substituted derivatives of dihydrofuran-2-one in experimental rodent models of pain K Sałat, B Filipek, K Więckowski, B Malawska Pharmacological Reports 61 (5), 807-818, 2009 | 29 | 2009 |
Synthesis and biological evaluation of new derivatives of 2-substituted 4-hydroxybutanamides as GABA uptake inhibitors K Kulig, K Więckowski, A Więckowska, J Gajda, B Pochwat, GC Höfner, ... European journal of medicinal chemistry 46 (1), 183-190, 2011 | 26 | 2011 |
Selective vs non-selective alpha-blockade prior to adrenalectomy for pheochromocytoma: systematic review and meta-analysis K Zawadzka, K Więckowski, P Małczak, M Wysocki, P Major, M Pędziwiatr, ... European Journal of Endocrinology 184 (6), 751-760, 2021 | 23 | 2021 |
A microwave-assisted multicomponent synthesis of substituted 3, 4-dihydroquinazolinones MY Stevens, K Wieckowski, P Wu, RT Sawant, LR Odell Organic & biomolecular chemistry 13 (7), 2044-2054, 2015 | 22 | 2015 |
Search for anticonvulsant and analgesic active derivatives of dihydrofuran-2(3H)-one K Więckowski, K Sałat, J Bytnar, M Bajda, B Filipek, JP Stables, ... Bioorganic & medicinal chemistry 20 (21), 6533-6544, 2012 | 21 | 2012 |
Analgesic, antioedematous and antioxidant activity of γ-butyrolactone derivatives in rodents K Salat, T Librowski, A Moniczewski, K Stanisz-Wallis, K Wieckowski, ... Behavioural Pharmacology 23 (4), 407-416, 2012 | 20 | 2012 |
Diagonal earlobe crease (Frank’s Sign) for diagnosis of coronary artery disease: a systematic review of diagnostic test accuracy studies K Więckowski, T Gallina, A Surdacki, B Chyrchel Journal of clinical medicine 10 (13), 2799, 2021 | 19 | 2021 |
Design, synthesis and pharmacological evaluation of\alpha-substituted N-benzylamides of\gamma-hydroxybutyric acid with potential GABA-ergic activity: part 6: search for new … B Malawska, K Kulig, J Gajda, D Szczeblewski, A Musiał, K Więckowski, ... Acta Poloniae Pharmaceutica. Drug Research 64 (2), 2007 | 17 | 2007 |
Risk factors for hemodynamic instability during laparoscopic pheochromocytoma resection: a retrospective cohort study M Pisarska-Adamczyk, K Zawadzka, K Więckowski, K Przęczek, P Major, ... Gland Surgery 10 (3), 892, 2021 | 14 | 2021 |