Emerging biological principles of metastasis AW Lambert, DR Pattabiraman, RA Weinberg Cell 168 (4), 670-691, 2017 | 3077 | 2017 |
Recovering gene interactions from single-cell data using data diffusion D Van Dijk, R Sharma, J Nainys, K Yim, P Kathail, AJ Carr, C Burdziak, ... Cell 174 (3), 716-729. e27, 2018 | 1504 | 2018 |
Tackling the cancer stem cells—what challenges do they pose? DR Pattabiraman, RA Weinberg Nature reviews Drug discovery 13 (7), 497-512, 2014 | 1129 | 2014 |
The systemic response to surgery triggers the outgrowth of distant immune-controlled tumors in mouse models of dormancy JA Krall, F Reinhardt, OA Mercury, DR Pattabiraman, MW Brooks, ... Science translational medicine 10 (436), eaan3464, 2018 | 389 | 2018 |
Activation of PKA leads to mesenchymal-to-epithelial transition and loss of tumor-initiating ability DR Pattabiraman, B Bierie, KI Kober, P Thiru, JA Krall, C Zill, F Reinhardt, ... Science 351 (6277), aad3680, 2016 | 343 | 2016 |
Integrin-β4 identifies cancer stem cell-enriched populations of partially mesenchymal carcinoma cells B Bierie, SE Pierce, C Kroeger, DG Stover, DR Pattabiraman, P Thiru, ... Proceedings of the National Academy of Sciences 114 (12), E2337-E2346, 2017 | 326 | 2017 |
Role and potential for therapeutic targeting of MYB in leukemia DR Pattabiraman, TJ Gonda Leukemia 27 (2), 269-277, 2013 | 187 | 2013 |
miR-139-5p is a regulator of metastatic pathways in breast cancer K Krishnan, AL Steptoe, HC Martin, DR Pattabiraman, K Nones, ... Rna 19 (12), 1767-1780, 2013 | 172 | 2013 |
Endothelial E-selectin inhibition improves acute myeloid leukaemia therapy by disrupting vascular niche-mediated chemoresistance V Barbier, J Erbani, C Fiveash, JM Davies, J Tay, MR Tallack, J Lowe, ... Nature Communications 11 (1), 1-15, 2020 | 155 | 2020 |
Interaction of c-Myb with p300 is required for the induction of acute myeloid leukemia (AML) by human AML oncogenes DR Pattabiraman, C McGirr, K Shakhbazov, V Barbier, K Krishnan, ... Blood 123 (17), 2682-2690, 2014 | 131 | 2014 |
Integrated genome-wide chromatin occupancy and expression analyses identify key myeloid pro-differentiation transcription factors repressed by Myb L Zhao, EA Glazov, DR Pattabiraman, F Al-Owaidi, P Zhang, MA Brown, ... Nucleic acids research 39 (11), 4664-4679, 2011 | 112 | 2011 |
Phenotypic heterogeneity driven by plasticity of the intermediate EMT state governs disease progression and metastasis in breast cancer MS Brown, B Abdollahi, OM Wilkins, H Lu, P Chakraborty, NB Ognjenovic, ... Science advances 8 (31), eabj8002, 2022 | 84 | 2022 |
Targeting the epithelial-to-mesenchymal transition: the case for differentiation-based therapy DR Pattabiraman, RA Weinberg Cold Spring Harbor symposia on quantitative biology 81, 11-19, 2016 | 73 | 2016 |
Hypoxia inducible factor (HIF)-2α accelerates disease progression in mouse models of leukemia and lymphoma but is not a poor prognosis factor in human AML CE Forristal, AL Brown, FM Helwani, IG Winkler, B Nowlan, V Barbier, ... Leukemia 29 (10), 2075-2085, 2015 | 47 | 2015 |
Mutations in multiple domains of c-Myb disrupt interaction with CBP/p300 and abrogate myeloid transforming ability DR Pattabiraman, J Sun, DH Dowhan, S Ishii, TJ Gonda Molecular Cancer Research 7 (9), 1477-1486, 2009 | 42 | 2009 |
A functional SUMO-interacting motif in the transactivation domain of c-Myb regulates its myeloid transforming ability T Sæther, DR Pattabiraman, AH Alm-Kristiansen, LT Vogt-Kielland, ... Oncogene 30 (2), 212-222, 2011 | 33 | 2011 |
A recessive screen for genes regulating hematopoietic stem cells P Papathanasiou, R Tunningley, DR Pattabiraman, P Ye, TJ Gonda, ... Blood 116 (26), 5849-5858, 2010 | 30 | 2010 |
Vascular niche E-selectin protects acute myeloid leukaemia stem cells from chemotherapy IG Winkler, V Barbier, DR Pattabiraman, TJ Gonda, JL Magnani, ... Blood 124 (21), 620-620, 2014 | 29 | 2014 |
Limiting Self-Renewal of the Basal Compartment by PKA Activation Induces Differentiation and Alters the Evolution of Mammary Tumors NB Ognjenovic, M Bagheri, GA Mohamed, K Xu, Y Chen, MAM Saleem, ... Developmental Cell 55 (5), 544-557. e6, 2020 | 25 | 2020 |
Quantifying the epithelial-to-mesenchymal transition (EMT) from bench to bedside MS Brown, KE Muller, DR Pattabiraman Cancers 14 (5), 1138, 2022 | 24 | 2022 |