| In vivo demonstration that α-synuclein oligomers are toxic B Winner, R Jappelli, SK Maji, PA Desplats, L Boyer, S Aigner, C Hetzer, ... Proceedings of the National Academy of Sciences 108 (10), 4194-4199, 2011 | 1743 | 2011 |
| A large-scale binding and functional map of human RNA-binding proteins EL Van Nostrand, P Freese, GA Pratt, X Wang, X Wei, R Xiao, SM Blue, ... Nature 583 (7818), 711-719, 2020 | 939 | 2020 |
| Wastewater sequencing reveals early cryptic SARS-CoV-2 variant transmission S Karthikeyan, JI Levy, P De Hoff, G Humphrey, A Birmingham, K Jepsen, ... Nature 609 (7925), 101-108, 2022 | 330 | 2022 |
| Elimination of toxic microsatellite repeat expansion RNA by RNA-targeting Cas9 R Batra, DA Nelles, E Pirie, SM Blue, RJ Marina, H Wang, IA Chaim, ... Cell 170 (5), 899-912. e10, 2017 | 297 | 2017 |
| Early transcriptional and epigenetic regulation of CD8+ T cell differentiation revealed by single-cell RNA sequencing B Kakaradov, J Arsenio, CE Widjaja, Z He, S Aigner, PJ Metz, B Yu, ... Nature immunology 18 (4), 422-432, 2017 | 249 | 2017 |
| Gene expression profiling of neural stem cells and their neuronal progeny reveals IGF2 as a regulator of adult hippocampal neurogenesis O Bracko, T Singer, S Aigner, M Knobloch, B Winner, J Ray, ... Journal of Neuroscience 32 (10), 3376-3387, 2012 | 241 | 2012 |
| Context-dependent functional compensation between Ythdf m6A reader proteins L Lasman, V Krupalnik, S Viukov, N Mor, A Aguilera-Castrejon, D Schneir, ... Genes & development 34 (19-20), 1373-1391, 2020 | 207 | 2020 |
| Multicellular self-assembled spheroidal model of the blood brain barrier E Urich, C Patsch, S Aigner, M Graf, R Iacone, PO Freskgård Scientific reports 3 (1), 1500, 2013 | 163 | 2013 |
| Cdk5 regulates accurate maturation of newborn granule cells in the adult hippocampus S Jessberger, S Aigner, GD Clemenson Jr, N Toni, DC Lie, Ö Karalay, ... PLoS biology 6 (11), e272, 2008 | 154 | 2008 |
| Enhanced CLIP uncovers IMP protein-RNA targets in human pluripotent stem cells important for cell adhesion and survival AE Conway, EL Van Nostrand, GA Pratt, S Aigner, ML Wilbert, ... Cell reports 15 (3), 666-679, 2016 | 151 | 2016 |
| Transcriptome-wide profiles of circular RNA and RNA-binding protein interactions reveal effects on circular RNA biogenesis and cancer pathway expression TLH Okholm, S Sathe, SS Park, AB Kamstrup, AM Rasmussen, A Shankar, ... Genome medicine 12, 1-22, 2020 | 139 | 2020 |
| Euplotes telomerase contains an La motif protein produced by apparent translational frameshifting S Aigner, J Lingner, KJ Goodrich, CA Grosshans, A Shevchenko, M Mann, ... The EMBO Journal, 2000 | 128 | 2000 |
| Gene dosage-dependent rescue of HSP neurite defects in SPG4 patients’ neurons S Havlicek, Z Kohl, HK Mishra, I Prots, E Eberhardt, N Denguir, H Wend, ... Human molecular genetics 23 (10), 2527-2541, 2014 | 122 | 2014 |
| mTORC1 inhibition corrects neurodevelopmental and synaptic alterations in a human stem cell model of tuberous sclerosis V Costa, S Aigner, M Vukcevic, E Sauter, K Behr, M Ebeling, T Dunkley, ... Cell reports 15 (1), 86-95, 2016 | 119 | 2016 |
| G4C2 repeat RNA initiates a POM121-mediated reduction in specific nucleoporins in C9orf72 ALS/FTD AN Coyne, BL Zaepfel, L Hayes, B Fitchman, Y Salzberg, EC Luo, ... Neuron 107 (6), 1124-1140. e11, 2020 | 116 | 2020 |
| Stem cell-derived neurons from autistic individuals with SHANK3 mutation show morphogenetic abnormalities during early development A Kathuria, P Nowosiad, R Jagasia, S Aigner, RD Taylor, LC Andreae, ... Molecular psychiatry 23 (3), 735-746, 2018 | 103 | 2018 |
| The RNA helicase DDX6 controls cellular plasticity by modulating P-body homeostasis B Di Stefano, EC Luo, C Haggerty, S Aigner, J Charlton, J Brumbaugh, ... Cell stem cell 25 (5), 622-638. e13, 2019 | 101 | 2019 |
| Hippocampus‐dependent learning is associated with adult neurogenesis in MRL/MpJ mice S Thuret, N Toni, S Aigner, GW Yeo, FH Gage Hippocampus 19 (7), 658-669, 2009 | 95 | 2009 |
| RNA aptamers as pathway-specific MAP kinase inhibitors SD Seiwert, TS Nahreini, S Aigner, NG Ahn, OC Uhlenbeck Chemistry & biology 7 (11), 833-843, 2000 | 93 | 2000 |
| The Euplotes La Motif Protein p43 Has Properties of a Telomerase-Specific Subunit S Aigner, J Postberg, HJ Lipps, TR Cech Biochemistry 42 (19), 5736-5747, 2003 | 79 | 2003 |
Gene Yeo PhD MBAProfessor of Cellular and Molecular Medicine at UC San DiegoVerified email at ucsd.edu
