annie huang
annie huang
professor of pediatrics, university of toronto
Verified email at
Cited by
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DNA methylation-based classification of central nervous system tumours
D Capper, DTW Jones, M Sill, V Hovestadt, D Schrimpf, D Sturm, ...
Nature 555 (7697), 469, 2018
Intertumoral heterogeneity within medulloblastoma subgroups
FMG Cavalli, M Remke, L Rampasek, J Peacock, DJH Shih, B Luu, ...
Cancer Cell 31 (6), 737-754. e6, 2017
Comprehensive analysis of hypermutation in human cancer
BB Campbell, N Light, D Fabrizio, M Zatzman, F Fuligni, R de Borja, ...
Cell 171 (5), 1042-1056. e10, 2017
Epigenomic alterations define lethal CIMP-positive ependymomas of infancy
SC Mack, H Witt, RM Piro, L Gu, S Zuyderduyn, AM StŁtz, X Wang, ...
Nature 506 (7489), 445, 2014
Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations
P Buczkowicz, C Hoeman, P Rakopoulos, S Pajovic, L Letourneau, ...
Nature genetics 46 (5), 451, 2014
Atypical teratoid/rhabdoid tumors are comprised of three epigenetic subgroups with distinct enhancer landscapes
PD Johann, S Erkek, M Zapatka, K Kerl, I Buchhalter, V Hovestadt, ...
Cancer cell 29 (3), 379-393, 2016
Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers
A Shlien, BB Campbell, R de Borja, LB Alexandrov, D Merico, D Wedge, ...
Nature genetics 47 (3), 257, 2015
Whole-genome profiling of pediatric diffuse intrinsic pontine gliomas highlights platelet-derived growth factor receptor α and poly (ADP-ribose) polymerase as potential†…
M Zarghooni, U Bartels, E Lee, P Buczkowicz, A Morrison, A Huang, ...
Journal of clinical oncology 28 (8), 1337-1344, 2010
Therapeutic and Prognostic Implications of BRAF V600E in Pediatric Low-Grade Gliomas.
A Lassaletta, M Zapotocky, M Mistry, V Ramaswamy, M Honnorat, ...
Journal of clinical oncology: official journal of the American Society of†…, 2017
BRAF mutation and CDKN2A deletion define a clinically distinct subgroup of childhood secondary high-grade glioma
M Mistry, N Zhukova, D Merico, P Rakopoulos, R Krishnatry, M Shago, ...
Journal of clinical oncology 33 (9), 1015, 2015
Frequent amplification of a chr19q13. 41 microRNA polycistron in aggressive primitive neuroectodermal brain tumors
M Li, KF Lee, Y Lu, I Clarke, D Shih, C Eberhart, VP Collins, T Van Meter, ...
Cancer cell 16 (6), 533-546, 2009
Embryonal tumor with abundant neuropil and true rosettes (ETANTR), ependymoblastoma, and medulloepithelioma share molecular similarity and comprise a single clinicopathological†…
A Korshunov, D Sturm, M Ryzhova, V Hovestadt, M Gessi, DTW Jones, ...
Acta neuropathologica 128 (2), 279-289, 2014
Integrated (epi)-genomic analyses identify subgroup-specific therapeutic targets in CNS rhabdoid tumors
J Torchia, B Golbourn, S Feng, KC Ho, P Sin-Chan, A Vasiljevic, ...
Cancer cell 30 (6), 891-908, 2016
Central nervous system atypical teratoid rhabdoid tumours: the Canadian Paediatric Brain Tumour Consortium experience
L Lafay-Cousin, C Hawkins, AS Carret, D Johnston, S Zelcer, B Wilson, ...
European journal of cancer 48 (3), 353-359, 2012
Fusion of TTYH1 with the C19MC microRNA cluster drives expression of a brain-specific DNMT3B isoform in the embryonal brain tumor ETMR
CL Kleinman, N Gerges, S Papillon-Cavanagh, P Sin-Chan, ...
Nature genetics 46 (1), 39, 2014
Phase II weekly vinblastine for chemotherapy-naive children with progressive low-grade glioma: a Canadian Pediatric Brain Tumor Consortium Study
A Lassaletta, K Scheinemann, SM Zelcer, J Hukin, BA Wilson, N Jabado, ...
Journal of Clinical Oncology 34 (29), 3537-3543, 2016
TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma
M Remke, V Ramaswamy, J Peacock, DJH Shih, C Koelsche, ...
Acta neuropathologica 126 (6), 917-929, 2013
Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling
SC Mack, KW Pajtler, L Chavez, K Okonechnikov, KC Bertrand, X Wang, ...
Nature 553 (7686), 101, 2018
KIF14 is a candidate oncogene in the 1q minimal region of genomic gain in multiple cancers
TW Corson, A Huang, MS Tsao, BL Gallie
Oncogene 24 (30), 4741, 2005
Wilms tumor locus on 11p13 defined by multiple CpG island-associated transcripts
L Bonetta, SE Kuehn, A Huang, DJ Law, LM Kalikin, M Koi, AE Reeve, ...
Science 250 (4983), 994-997, 1990
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