Marcel A. van den Broek
Marcel A. van den Broek
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CRISPR/Cas9: a molecular Swiss army knife for simultaneous introduction of multiple genetic modifications in Saccharomyces cerevisiae
R Mans, HM van Rossum, M Wijsman, A Backx, NGA Kuijpers, ...
FEMS yeast research 15 (2), 2015
De novo sequencing, assembly and analysis of the genome of the laboratory strain Saccharomyces cerevisiae CEN. PK113-7D, a model for modern industrial biotechnology
JF Nijkamp, M van den Broek, E Datema, S de Kok, L Bosman, MA Luttik, ...
Microbial cell factories 11 (1), 1-17, 2012
S. cerevisiae× S. eubayanus interspecific hybrid, the best of both worlds and beyond
M Hebly, A Brickwedde, I Bolat, MRM Driessen, EAF de Hulster, ...
FEMS Yeast Research 15 (3), 2015
A versatile, efficient strategy for assembly of multi-fragment expression vectors in Saccharomyces cerevisiae using 60 bp synthetic recombination sequences
NGA Kuijpers, D Solis-Escalante, L Bosman, M van den Broek, JT Pronk, ...
Microbial cell factories 12 (1), 1-13, 2013
A new laboratory evolution approach to select for constitutive acetic acid tolerance in Saccharomyces cerevisiae and identification of causal mutations
D González-Ramos, ARG De Vries, SS Grijseels, MC Van Berkum, ...
Biotechnology for biofuels 9 (1), 1-18, 2016
Genome-scale analyses of butanol tolerance in Saccharomyces cerevisiae reveal an essential role of protein degradation
D González-Ramos, M van den Broek, AJA van Maris, JT Pronk, ...
Biotechnology for biofuels 6 (1), 1-18, 2013
De novo detection of copy number variation by co-assembly
JF Nijkamp, MA van den Broek, JMA Geertman, MJT Reinders, ...
Bioinformatics 28 (24), 3195-3202, 2012
Combinatorial effects of environmental parameters on transcriptional regulation in Saccharomyces cerevisiae: a quantitative analysis of a compendium of chemostat-based …
TA Knijnenburg, JMG Daran, MA van den Broek, PAS Daran-Lapujade, ...
BMC genomics 10 (1), 1-20, 2009
Chromosomal copy number variation in Saccharomyces pastorianus is evidence for extensive genome dynamics in industrial lager brewing strains
M Van den Broek, I Bolat, JF Nijkamp, E Ramos, MAH Luttik, F Koopman, ...
Applied and environmental microbiology 81 (18), 6253-6267, 2015
Nanopore sequencing enables near-complete de novo assembly of Saccharomyces cerevisiae reference strain CEN. PK113-7D
AN Salazar, AR Gorter de Vries, M van den Broek, M Wijsman, ...
FEMS yeast research 17 (7), 2017
Integrating genome assemblies with MAIA
J Nijkamp, W Winterbach, M Van den Broek, JM Daran, M Reinders, ...
Bioinformatics 26 (18), i433-i439, 2010
Mutations in PMR1 stimulate xylose isomerase activity and anaerobic growth on xylose of engineered Saccharomyces cerevisiae by influencing manganese homeostasis
MD Verhoeven, M Lee, L Kamoen, M Van Den Broek, DB Janssen, ...
Scientific reports 7 (1), 1-11, 2017
CRISPR-Cas9 mediated gene deletions in lager yeast Saccharomyces pastorianus
ARG De Vries, PA De Groot, M Van Den Broek, JMG Daran
Microbial cell factories 16 (1), 1-18, 2017
Pathway swapping: Toward modular engineering of essential cellular processes
NGA Kuijpers, D Solis-Escalante, MAH Luttik, MMM Bisschops, ...
Proceedings of the National Academy of Sciences 113 (52), 15060-15065, 2016
Evolutionary engineering in chemostat cultures for improved maltotriose fermentation kinetics in Saccharomyces pastorianus lager brewing yeast
A Brickwedde, M van den Broek, JMA Geertman, F Magalhăes, ...
Frontiers in microbiology 8, 1690, 2017
Selection of Pof-Saccharomyces eubayanus variants for the construction of S. cerevisiae× S. eubayanus hybrids with reduced 4-vinyl guaiacol formation
JA Diderich, SM Weening, M van den Broek, JT Pronk, JMG Daran
Frontiers in microbiology 9, 1640, 2018
Laboratory evolution of a biotin-requiring Saccharomyces cerevisiae strain for full biotin prototrophy and identification of causal mutations
JM Bracher, E de Hulster, CC Koster, M van den Broek, JMG Daran, ...
Applied and environmental microbiology 83 (16), e00892-17, 2017
Elimination of sucrose transport and hydrolysis in Saccharomyces cerevisiae: a platform strain for engineering sucrose metabolism
WL Marques, R Mans, ER Marella, RL Cordeiro, M van den Broek, ...
FEMS yeast research 17 (1), fox006, 2017
The genome sequence of the popular hexose-transport-deficient Saccharomyces cerevisiae strain EBY.VW4000 reveals LoxP/Cre-induced translocations and …
D Solis-Escalante, M van den Broek, NGA Kuijpers, JT Pronk, E Boles, ...
FEMS yeast research 15 (2), fou004, 2015
Laboratory evolution of a Saccharomyces cerevisiae× S. eubayanus hybrid under simulated lager-brewing conditions
AR Gorter de Vries, MA Voskamp, ACA Van Aalst, LH Kristensen, ...
Frontiers in genetics 10, 242, 2019
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