| Angucyclines: Biosynthesis, mode-of-action, new natural products, and synthesis MK Kharel, P Pahari, MD Shepherd, N Tibrewal, SE Nybo, KA Shaaban, ... Natural product reports 29 (2), 264-325, 2012 | 351 | 2012 |
| Baeyer–Villiger C–C bond cleavage reaction in gilvocarcin and jadomycin biosynthesis N Tibrewal, P Pahari, G Wang, MK Kharel, C Morris, T Downey, Y Hou, ... Journal of the American Chemical Society 134 (44), 18181-18184, 2012 | 101 | 2012 |
| Amalgamation of Nucleosides and Amino Acids in Antibiotic Biosynthesis: Discovery of an l-Threonine:Uridine-5′-Aldehyde Transaldolase S Barnard-Britson, X Chi, K Nonaka, AP Spork, N Tibrewal, A Goswami, ... Journal of the American Chemical Society 134 (45), 18514-18517, 2012 | 79 | 2012 |
| Biocatalysts for natural product biosynthesis N Tibrewal, Y Tang Annual review of chemical and biomolecular engineering 5, 347-366, 2014 | 68 | 2014 |
| Functional identification of valerena-1, 10-diene synthase, a terpene synthase catalyzing a unique chemical cascade in the biosynthesis of biologically active sesquiterpenes in … YS Yeo, SE Nybo, AG Chittiboyina, AD Weerasooriya, YH Wang, ... Journal of Biological Chemistry 288 (5), 3163-3173, 2013 | 53 | 2013 |
| Selective inhibitors of mTORC1 activate 4EBP1 and suppress tumor growth BJ Lee, JA Boyer, GL Burnett, AP Thottumkara, N Tibrewal, SL Wilson, ... Nature chemical biology 17 (10), 1065-1074, 2021 | 44 | 2021 |
| Radical biocatalysis: Using non-natural single electron transfer mechanisms to access new enzymatic functions TK Hyster Synlett 31 (03), 248-254, 2020 | 42 | 2020 |
| The muraminomicin biosynthetic gene cluster and enzymatic formation of the 2-deoxyaminoribosyl appendage X Chi, S Baba, N Tibrewal, M Funabashi, K Nonaka, SG Van Lanen MedChemComm 4 (1), 239-243, 2013 | 28 | 2013 |
| Roles of the Synergistic Reductive O-Methyltransferase GilM and of O-Methyltransferase GilMT in the Gilvocarcin Biosynthetic Pathway N Tibrewal, TE Downey, SG Van Lanen, E Ul Sharif, GA O’Doherty, ... Journal of the American Chemical Society 134 (30), 12402-12405, 2012 | 28 | 2012 |
| Evaluation of hadacidin analogues N Tibrewal, GI Elliott Bioorganic & medicinal chemistry letters 21 (1), 517-519, 2011 | 25 | 2011 |
| Disruption of de Novo Adenosine Triphosphate (ATP) Biosynthesis Abolishes Virulence in Cryptococcus neoformans RD Blundell, SJ Williams, SDM Arras, JL Chitty, KL Blake, DJ Ericsson, ... ACS infectious diseases 2 (9), 651-663, 2016 | 22 | 2016 |
| RMC-4550, an allosteric inhibitor of SHP2: Synthesis, structure, and anti-tumor activity ES Koltun, N Aay, A Buckl, AS Jogalekar, G Kiss, A Marquez, KT Mellem, ... Cancer Research 78 (13_Supplement), 4878-4878, 2018 | 6 | 2018 |
| Rapamycin analogs as mtor inhibitors JB Aggen, AP Thottumkara, GL Burnett, MJE Gliedt, K Gert, W Won, ... US Patent App. 16/669,319, 2021 | 2 | 2021 |
| Design, Synthesis and Evaluation of AdSS Bisubstrate Inhibitors N Tibrewal, GI Elliott ChemMedChem 15 (23), 2269-2272, 2020 | 2 | 2020 |
| Rapamycin analogs as mtor inhibitors C Semko, J Pitzen, G Wang, N Tibrewal, JB Aggen, AP Thottumkara, ... | 2 | 2018 |
| Abstract PR04: 4EBP1 reactivation by potent and selective bi-steric inhibitors of mTORC1 N Tibrewal, JB Aggen, AI Bassan, GL Burnett, J Evans, MJ Gliedt, D Hsieh, ... Molecular Cancer Research 18 (10_Supplement), PR04-PR04, 2020 | 1 | 2020 |
| Rapamycin analogs as mtor inhibitors JB Aggen, AP Thottumkara, GL Burnett, MJE Gliedt, K Gert, W Won, ... US Patent App. 17/693,225, 2023 | | 2023 |
| Discovery and characterization of potent and selective AXL receptor tyrosine kinase inhibitor AB801 D Miles, S Paprcka, C Foley, S Qu, M Lamani, S Paladugu, HT Huang, ... European Journal of Cancer 174, S103, 2022 | | 2022 |
| HPK1 inhibition enhances T cell activation and relieves the immunosuppressive phenotype of inhibitory signals found in the tumor microenvironment RK Singh, R Rayaji, B Patel, K Zhang, S Marubayashi, S Cho, ... Cancer Research 82 (12), 2022 | | 2022 |
| 854 HPK1 inhibition relieves suppression downstream of TCR activation to drive enhanced cytokine production and antigen-specific killing, an effect that is further enhanced by … R Singh, B Patel, R Rayaji, S Marubayashi, S Cho, S Garrido-Shaqfeh, ... J Immunother 10 (2), A1-A1595, 2022 | | 2022 |
Madan KharelAssistant Prof. of Pharmaceutical sciences, University of Maryland Eastern ShoreVerified email at umes.edu
