Follow
I Can Kazan
Title
Cited by
Cited by
Year
Plant-expressed cocaine hydrolase variants of butyrylcholinesterase exhibit altered allosteric effects of cholinesterase activity and increased inhibitor sensitivity
KE Larrimore, IC Kazan, L Kannan, RP Kendle, T Jamal, M Barcus, ...
Scientific reports 7 (1), 10419, 2017
322017
Protein folding stability and binding interactions through the lens of evolution: a dynamical perspective
T Modi, P Campitelli, IC Kazan, SB Ozkan
Current opinion in structural biology 66, 207-215, 2021
302021
Dynamic coupling of residues within proteins as a mechanistic foundation of many enigmatic pathogenic missense variants
NJ Ose, BM Butler, A Kumar, IC Kazan, M Sanderford, S Kumar, ...
PLoS computational biology 18 (4), e1010006, 2022
182022
Coevolving residues inform protein dynamics profiles and disease susceptibility of nSNVs
BM Butler, IC Kazan, A Kumar, SB Ozkan
PLoS computational biology 14 (11), e1006626, 2018
142018
The role of rigid residues in modulating TEM-1 β-lactamase function and thermostability
B Kolbaba-Kartchner, IC Kazan, JH Mills, SB Ozkan
International journal of molecular sciences 22 (6), 2895, 2021
82021
Design of novel cyanovirin-N variants by modulation of binding dynamics through distal mutations
IC Kazan, P Sharma, MI Rahman, A Bobkov, R Fromme, G Ghirlanda, ...
Elife 11, e67474, 2022
72022
Investigating the allosteric response of the PICK1 PDZ domain to different ligands with all‐atom simulations
AO Stevens, IC Kazan, B Ozkan, Y He
Protein Science 31 (12), e4474, 2022
72022
Allosteric regulatory control in dihydrofolate reductase is revealed by dynamic asymmetry
IC Kazan, JH Mills, SB Ozkan
Protein Science 32 (8), e4700, 2023
42023
A method for the incorporation of protein dynamics into computational enzyme design using the Rosetta software suite
BK Kartchner, IC Kazan, SB Ozkan, JH Mills
Biophysical Journal 118 (3), 320a-321a, 2020
12020
Plant-expressed cocaine hydrolase variants of butyrylcholinesterase exhibit altered allosteric effects of cholinesterase activity and increased inhibitor sensitivity (vol 7 …
KE Larrimore, I Kazan, L Kannan, R Kendle, T Jamal, M Barcus, A Bolia, ...
SCIENTIFIC REPORTS 8, 2018
12018
Enhancing deep learning model design through protein dynamics information integration
J Lu, ICJ Kazan, BK Kartchner, N Huynh, JH Mills, SB Ozkan
Biophysical Journal 123 (3), 207a-208a, 2024
2024
Engineering gain-of-function mutants of a WW domain by dynamics and structural analysis
ICJ Kazan, J Lu, MI Rahman, N Halloran, AA Bobkov, SB Ozkan, ...
Biophysical Journal 123 (3), 64a, 2024
2024
Some mechanistic underpinnings of molecular adaptations of SARS-COV-2 spike protein by integrating candidate adaptive polymorphisms with protein dynamics
NJ Ose, P Campitelli, T Modi, IC Kazan, S Kumar, SB Ozkan
bioRxiv, 2023
2023
Engineering gain‐of‐function mutants of a WW domain by dynamics and structural analysis
J Lu, MI Rahman, IC Kazan, NR Halloran, AA Bobkov, SB Ozkan, ...
Protein Science 32 (9), e4759, 2023
2023
Understanding the evolution of cold sensing and menthol activation in TRPM8
N Ramesh, D Luu, KH Shah, ICJ Kazan, SB Ozkan, WD Van Horn
Biophysical journal 122 (3), 197a, 2023
2023
Allosteric regulatory control in dihydrofolate reductase (DHFR) revealed with dynamic asymmetry in unliganded ensemble
ICJ Kazan, JH Mills, SB Ozkan
Biophysical Journal 122 (3), 48a, 2023
2023
Evolutionary Guided Molecular Dynamics Driven Protein Design
IC Kazan
Arizona State University, 2023
2023
Track: Protein and Ligand-A New Marriage Between an Old Couple Functional Ancestral Reconstruction of the Cold and Menthol Sensor TRPM8
D Luu, K Shah, N Ramesh, I Kazan, SB Ozkan, W Van Horn
PROTEIN SCIENCE 32, 2023
2023
Adaptive Evolution of SARS-CoV-2: A Perspective from Dynamics
IC Kazan, SB Ozkan
Biophysical Journal 120 (3), 300a-301a, 2021
2021
Design of novel CV-N variants: Modulation of binding dynamics through distal mutations
IC Kazan, P Sharma, A Bobkov, R Fromme, G Ghirlanda, SB Ozkan
bioRxiv, 2020.12. 21.423842, 2020
2020
The system can't perform the operation now. Try again later.
Articles 1–20