Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position JD Buenrostro, PG Giresi, LC Zaba, HY Chang, WJ Greenleaf Nature methods 10 (12), 1213-1218, 2013 | 6325 | 2013 |
ATAC‐seq: a method for assaying chromatin accessibility genome‐wide JD Buenrostro, B Wu, HY Chang, WJ Greenleaf Current protocols in molecular biology 109 (1), 21.29. 1-21.29. 9, 2015 | 3449 | 2015 |
Single-cell chromatin accessibility reveals principles of regulatory variation JD Buenrostro, B Wu, UM Litzenburger, D Ruff, ML Gonzales, MP Snyder, ... Nature 523 (7561), 486-490, 2015 | 2229 | 2015 |
An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues MR Corces, AE Trevino, EG Hamilton, PG Greenside, ... Nature methods 14 (10), 959-962, 2017 | 2043 | 2017 |
Chromatin accessibility and the regulatory epigenome SL Klemm, Z Shipony, WJ Greenleaf Nature Reviews Genetics 20 (4), 207-220, 2019 | 1534 | 2019 |
chromVAR: inferring transcription-factor-associated accessibility from single-cell epigenomic data AN Schep, B Wu, JD Buenrostro, WJ Greenleaf Nature methods 14 (10), 975-978, 2017 | 1239 | 2017 |
Lineage-specific and single-cell chromatin accessibility charts human hematopoiesis and leukemia evolution MR Corces, JD Buenrostro, B Wu, PG Greenside, SM Chan, JL Koenig, ... Nature genetics 48 (10), 1193-1203, 2016 | 1143 | 2016 |
Direct observation of base-pair stepping by RNA polymerase EA Abbondanzieri, WJ Greenleaf, JW Shaevitz, R Landick, SM Block Nature 438 (7067), 460-465, 2005 | 1073 | 2005 |
HiChIP: efficient and sensitive analysis of protein-directed genome architecture MR Mumbach, AJ Rubin, RA Flynn, C Dai, PA Khavari, WJ Greenleaf, ... Nature methods 13 (11), 919-922, 2016 | 1062 | 2016 |
The chromatin accessibility landscape of primary human cancers MR Corces, JM Granja, S Shams, BH Louie, JA Seoane, W Zhou, ... Science 362 (6413), eaav1898, 2018 | 1060 | 2018 |
ArchR is a scalable software package for integrative single-cell chromatin accessibility analysis JM Granja, MR Corces, SE Pierce, ST Bagdatli, H Choudhry, HY Chang, ... Nature genetics 53 (3), 403-411, 2021 | 883 | 2021 |
Massively parallel single-cell chromatin landscapes of human immune cell development and intratumoral T cell exhaustion AT Satpathy, JM Granja, KE Yost, Y Qi, F Meschi, GP McDermott, ... Nature biotechnology 37 (8), 925-936, 2019 | 772 | 2019 |
Integrated single-cell analysis maps the continuous regulatory landscape of human hematopoietic differentiation JD Buenrostro, MR Corces, CA Lareau, B Wu, AN Schep, MJ Aryee, ... Cell 173 (6), 1535-1548. e16, 2018 | 673 | 2018 |
High-resolution, single-molecule measurements of biomolecular motion WJ Greenleaf, MT Woodside, SM Block Annu. Rev. Biophys. Biomol. Struct. 36 (1), 171-190, 2007 | 629 | 2007 |
Origin and differentiation of human memory CD8 T cells after vaccination RS Akondy, M Fitch, S Edupuganti, S Yang, HT Kissick, KW Li, ... Nature 552 (7685), 362-367, 2017 | 540 | 2017 |
Artificial cavitation nuclei significantly enhance acoustically induced cell transfection WJ Greenleaf, ME Bolander, G Sarkar, MB Goldring, JF Greenleaf Ultrasound in medicine & biology 24 (4), 587-595, 1998 | 490 | 1998 |
Enhancer connectome in primary human cells identifies target genes of disease-associated DNA elements MR Mumbach, AT Satpathy, EA Boyle, C Dai, BG Gowen, SW Cho, ... Nature genetics 49 (11), 1602-1612, 2017 | 485 | 2017 |
Direct observation of hierarchical folding in single riboswitch aptamers WJ Greenleaf, KL Frieda, DAN Foster, MT Woodside, SM Block Science 319 (5863), 630-633, 2008 | 467 | 2008 |
The human tumor atlas network: charting tumor transitions across space and time at single-cell resolution O Rozenblatt-Rosen, A Regev, P Oberdoerffer, T Nawy, A Hupalowska, ... Cell 181 (2), 236-249, 2020 | 442 | 2020 |
The human body at cellular resolution: the NIH Human Biomolecular Atlas Program Caltech-UW TMC Cai Long lcai@ caltech. edu 21 b Shendure Jay 9 Trapnell Cole ... Nature 574 (7777), 187-192, 2019 | 442 | 2019 |