| Identification of a BRCA1-mRNA splicing complex required for efficient DNA repair and maintenance of genomic stability KI Savage, JJ Gorski, EM Barros, GW Irwin, L Manti, AJ Powell, ... Molecular cell 54 (3), 445-459, 2014 | 198 | 2014 |
| Transcription factor activities enhance markers of drug sensitivity in cancer L Garcia-Alonso, F Iorio, A Matchan, N Fonseca, P Jaaks, G Peat, ... Cancer research 78 (3), 769-780, 2018 | 172 | 2018 |
| Challenging the cancer molecular stratification dogma: intratumoral heterogeneity undermines consensus molecular subtypes and potential diagnostic value in colorectal cancer PD Dunne, DG McArt, CA Bradley, PG O'Reilly, HL Barrett, R Cummins, ... Clinical Cancer Research 22 (16), 4095-4104, 2016 | 161 | 2016 |
| BRCA1 deficiency exacerbates estrogen-induced DNA damage and genomic instability KI Savage, KB Matchett, EM Barros, KM Cooper, GW Irwin, JJ Gorski, ... Cancer research 74 (10), 2773-2784, 2014 | 146 | 2014 |
| Evidence for alteration of EZH2, BMI1, and KDM6A and epigenetic reprogramming in human papillomavirus type 16 E6/E7-expressing keratinocytes PL Hyland, SS McDade, R McCloskey, GJ Dickson, K Arthur, DJ McCance, ... Journal of virology 85 (21), 10999-11006, 2011 | 126 | 2011 |
| Genome-wide association study identifies a common variant in RAD51B associated with male breast cancer risk N Orr, A Lemnrau, R Cooke, O Fletcher, K Tomczyk, M Jones, N Johnson, ... Nature genetics 44 (11), 1182-1184, 2012 | 120 | 2012 |
| The septin-binding protein anillin is overexpressed in diverse human tumors PA Hall, CB Todd, PL Hyland, SS McDade, H Grabsch, M Dattani, ... Clinical cancer research 11 (19), 6780-6786, 2005 | 111 | 2005 |
| Genome-wide analysis of p63 binding sites identifies AP-2 factors as co-regulators of epidermal differentiation SS McDade, AE Henry, GP Pivato, I Kozarewa, C Mitsopoulos, K Fenwick, ... Nucleic acids research 40 (15), 7190-7206, 2012 | 103 | 2012 |
| MicroRNA 203 expression in keratinocytes is dependent on regulation of p53 levels by E6 DJ McKenna, SS McDade, D Patel, DJ McCance Journal of virology 84 (20), 10644-10652, 2010 | 97 | 2010 |
| Synthetic Lethal Targeting of ARID1A-Mutant Ovarian Clear Cell Tumors with Dasatinib RE Miller, R Brough, I Bajrami, CT Williamson, S McDade, J Campbell, ... Molecular cancer therapeutics 15 (7), 1472-1484, 2016 | 95 | 2016 |
| Cancer-cell intrinsic gene expression signatures overcome intratumoural heterogeneity bias in colorectal cancer patient classification PD Dunne, M Alderdice, PG O'Reilly, AC Roddy, AMB McCorry, ... Nature communications 8 (1), 15657, 2017 | 90 | 2017 |
| Role of ΔNp63γ in epithelial to mesenchymal transition J Lindsay, SS McDade, A Pickard, KD McCloskey, DJ McCance Journal of Biological Chemistry 286 (5), 3915-3924, 2011 | 88 | 2011 |
| Validation of a Metastatic Assay using biopsies to improve risk stratification in patients with prostate cancer treated with radical radiation therapy S Jain, CA Lyons, SM Walker, S McQuaid, SO Hynes, DM Mitchell, ... Annals of Oncology 29 (1), 215-222, 2018 | 87 | 2018 |
| Recommendations for determining HPV status in patients with oropharyngeal cancers under TNM8 guidelines: a two-tier approach SG Craig, LA Anderson, AG Schache, M Moran, L Graham, K Currie, ... British Journal of Cancer 120 (8), 827-833, 2019 | 79 | 2019 |
| Genome-wide characterization reveals complex interplay between TP53 and TP63 in response to genotoxic stress SS McDade, D Patel, M Moran, J Campbell, K Fenwick, I Kozarewa, ... Nucleic acids research 42 (10), 6270-6285, 2014 | 73 | 2014 |
| A whole‐genome massively parallel sequencing analysis of BRCA1 mutant oestrogen receptor‐negative and ‐positive breast cancers R Natrajan, A Mackay, MB Lambros, B Weigelt, PM Wilkerson, E Manie, ... The Journal of pathology 227 (1), 29-41, 2012 | 73 | 2012 |
| Translational control of SEPT9 isoforms is perturbed in disease SS McDade, PA Hall, SEH Russell Human molecular genetics 16 (7), 742-752, 2007 | 73 | 2007 |
| SEPT9_v4 expression induces morphological change, increased motility and disturbed polarity AD Chacko, PL Hyland, SS McDade, PW Hamilton, SEH Russell, PA Hall The Journal of Pathology: A Journal of the Pathological Society of Great …, 2005 | 72 | 2005 |
| Transcriptional subtyping and CD8 immunohistochemistry identifies patients with stage II and III colorectal cancer with poor prognosis who benefit from adjuvant chemotherapy WL Allen, PD Dunne, S McDade, E Scanlon, M Loughrey, HG Coleman, ... JCO precision oncology 2, 1-15, 2018 | 67 | 2018 |
| TNF-α synergises with IFN-γ to induce caspase-8-JAK1/2-STAT1-dependent death of intestinal epithelial cells JA Woznicki, N Saini, P Flood, S Rajaram, CM Lee, P Stamou, A Skowyra, ... Cell death & disease 12 (10), 864, 2021 | 65 | 2021 |
