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Gary Mirams
Gary Mirams
Other namesGary Richard Mirams
Centre for Mathematical Medicine & Biology, University of Nottingham
Verified email at nottingham.ac.uk - Homepage
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Cited by
Cited by
Year
Chaste: an open source C++ library for computational physiology and biology
GR Mirams, CJ Arthurs, MO Bernabeu, R Bordas, J Cooper, A Corrias, ...
PLoS computational biology 9 (3), e1002970, 2013
4412013
Simulation of multiple ion channel block provides improved early prediction of compounds’ clinical torsadogenic risk
GR Mirams, Y Cui, A Sher, M Fink, J Cooper, BM Heath, NC McMahon, ...
Cardiovascular research 91 (1), 53, 2011
3042011
Chaste: a test-driven approach to software development for biological modelling
J Pitt-Francis, P Pathmanathan, MO Bernabeu, R Bordas, J Cooper, ...
Computer Physics Communications 180 (12), 2452-2471, 2009
2842009
An integrative computational model for intestinal tissue renewal
IMM Van Leeuwen, GR Mirams, A Walter, A Fletcher, P Murray, J Osborne, ...
Cell proliferation 42 (5), 617-636, 2009
1692009
Application of human stem cell-derived cardiomyocytes in safety pharmacology requires caution beyond hERG
MKB Jonsson, MA Vos, GR Mirams, G Duker, P Sartipy, TP de Boer, ...
Journal of Molecular and Cellular Cardiology 52 (5), 998-1008, 2012
1502012
Hydroxychloroquine reduces heart rate by modulating the hyperpolarization-activated current I f: Novel electrophysiological insights and therapeutic potential
RA Capel, N Herring, M Kalla, A Yavari, GR Mirams, G Douglas, G Bub, ...
Heart Rhythm 12 (10), 2186-2194, 2015
1482015
Uncertainty and variability in models of the cardiac action potential: Can we build trustworthy models?
RH Johnstone, ETY Chang, R Bardenet, TP De Boer, DJ Gavaghan, ...
Journal of molecular and cellular cardiology 96, 49-62, 2016
1422016
A hybrid approach to multi-scale modelling of cancer
JM Osborne, A Walter, SK Kershaw, GR Mirams, AG Fletcher, ...
Philosophical Transactions of the Royal Society A: Mathematical, Physical …, 2010
1412010
A computational study of discrete mechanical tissue models
P Pathmanathan, J Cooper, A Fletcher, G Mirams, P Murray, J Osborne, ...
Physical biology 6 (3), 036001, 2009
1332009
Uncertainty and variability in computational and mathematical models of cardiac physiology
GR Mirams, P Pathmanathan, RA Gray, P Challenor, RH Clayton
The Journal of physiology 594 (23), 6833-6847, 2016
1282016
Computational assessment of drug‐induced effects on the electrocardiogram: from ion channel to body surface potentials
N Zemzemi, MO Bernabeu, J Saiz, J Cooper, P Pathmanathan, ...
British Journal of Pharmacology 168 (3), 718-733, 2012
1202012
Application of cardiac electrophysiology simulations to pro‐arrhythmic safety testing
GR Mirams, MR Davies, Y Cui, P Kohl, D Noble
British Journal of Pharmacology 167 (5), 932-945, 2012
1062012
Assessment of an in silico mechanistic model for proarrhythmia risk prediction under the CiPA initiative
Z Li, WW Wu, J Sheng, PN Tran, M Wu, A Ranolph, RH Johnstone, ...
Clinical Pharmacology & Therapeutics, 2018
1022018
Prediction of Thorough QT study results using action potential simulations based on ion channel screens
GR Mirams, MR Davies, SJ Brough, MH Bridgland-Taylor, Y Cui, ...
Journal of pharmacological and toxicological methods 70 (3), 246-254, 2014
912014
Systems Toxicology: Real World Applications and Opportunities
T Hartung, RE FitzGerald, P Jennings, GR Mirams, MC Peitsch, ...
Chemical Research in Toxicology 30 (4), 870, 2017
882017
mRNA expression levels in failing human hearts predict cellular electrophysiological remodeling: a population-based simulation study
J Walmsley, JF Rodriguez, GR Mirams, K Burrage, IR Efimov, ...
PloS one 8 (2), e56359, 2013
792013
Variability in high-throughput ion-channel screening data and consequences for cardiac safety assessment
RC Elkins, MR Davies, SJ Brough, DJ Gavaghan, Y Cui, N Abi-Gerges, ...
Journal of pharmacological and toxicological methods 68 (1), 112-122, 2013
782013
A theoretical investigation of the effect of proliferation and adhesion on monoclonal conversion in the colonic crypt
GR Mirams, AG Fletcher, PK Maini, HM Byrne
Journal of Theoretical Biology 312 (7), 143-156, 2012
732012
Minimum Information about a Cardiac Electrophysiology Experiment (MICEE): standardised reporting for model reproducibility, interoperability, and data sharing
TA Quinn, S Granite, MA Allessie, C Antzelevitch, C Bollensdorff, G Bub, ...
Progress in biophysics and molecular biology 107 (1), 4-10, 2011
722011
Recent developments in using mechanistic cardiac modelling for drug safety evaluation
MR Davies, K Wang, GR Mirams, A Caruso, D Noble, A Walz, T Lavé, ...
Drug discovery today 21 (6), 924-938, 2016
672016
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