Etomoxir actions on regulatory and memory T cells are independent of Cpt1a-mediated fatty acid oxidation B Raud, DG Roy, AS Divakaruni, TN Tarasenko, R Franke, EH Ma, ... Cell metabolism 28 (3), 504-515. e7, 2018 | 310 | 2018 |
Metabolic profiling using stable isotope tracing reveals distinct patterns of glucose utilization by physiologically activated CD8+ T cells EH Ma, MJ Verway, RM Johnson, DG Roy, M Steadman, S Hayes, ... Immunity 51 (5), 856-870. e5, 2019 | 294 | 2019 |
Neoadjuvant oncolytic virotherapy before surgery sensitizes triple-negative breast cancer to immune checkpoint therapy MC Bourgeois-Daigneault, DG Roy, AS Aitken, N El Sayes, NT Martin, ... Science translational medicine 10 (422), eaao1641, 2018 | 293 | 2018 |
Methionine metabolism shapes T helper cell responses through regulation of epigenetic reprogramming DG Roy, J Chen, V Mamane, EH Ma, BM Muhire, RD Sheldon, ... Cell metabolism 31 (2), 250-266. e9, 2020 | 223 | 2020 |
Targeting tumor vasculature with an oncolytic virus CJ Breitbach, NS De Silva, TJ Falls, U Aladl, L Evgin, J Paterson, YY Sun, ... Molecular Therapy 19 (5), 886-894, 2011 | 212 | 2011 |
Vesicular stomatitis virus oncolysis is potentiated by impairing mTORC1-dependent type I IFN production T Alain, XQ Lun, Y Martineau, P Sean, B Pulendran, E Petroulakis, ... Proceedings of the National Academy of Sciences 107 (4), 1576-1581, 2010 | 157 | 2010 |
Oncolytic vesicular stomatitis virus expressing interferon-σ has enhanced therapeutic activity MC Bourgeois-Daigneault, DG Roy, T Falls, K Twumasi-Boateng, ... Molecular Therapy-Oncolytics 3, 2016 | 87 | 2016 |
Combination of Paclitaxel and MG1 oncolytic virus as a successful strategy for breast cancer treatment MC Bourgeois-Daigneault, LE St-Germain, DG Roy, A Pelin, AS Aitken, ... Breast Cancer Research 18, 1-10, 2016 | 85 | 2016 |
Cell carriers for oncolytic viruses: current challenges and future directions DG Roy, JC Bell Oncolytic virotherapy, 47-56, 2013 | 81 | 2013 |
MicroRNAs regulate the immunometabolic response to viral infection in the liver R Singaravelu, S O'hara, DM Jones, R Chen, NG Taylor, P Srinivasan, ... Nature chemical biology 11 (12), 988-993, 2015 | 67 | 2015 |
Mitochondrial cyclophilin D regulates T cell metabolic responses and disease tolerance to tuberculosis F Tzelepis, J Blagih, N Khan, J Gillard, L Mendonca, DG Roy, EH Ma, ... Science immunology 3 (23), eaar4135, 2018 | 59 | 2018 |
Activation of peroxisome proliferator-activated receptors α and δ synergizes with inflammatory signals to enhance adoptive cell therapy SD Saibil, M St. Paul, RC Laister, CR Garcia-Batres, K Israni-Winger, ... Cancer Research 79 (3), 445-451, 2019 | 53 | 2019 |
Model-based rational design of an oncolytic virus with improved therapeutic potential F Le Bœuf, C Batenchuk, M Vähä-Koskela, S Breton, D Roy, C Lemay, ... Nature communications 4 (1), 1974, 2013 | 53 | 2013 |
Bacterial-mediated knockdown of tumor resistance to an oncolytic virus enhances therapy M Cronin, F Le Boeuf, C Murphy, DG Roy, T Falls, JC Bell, M Tangney Molecular Therapy 22 (6), 1188-1197, 2014 | 51 | 2014 |
Taking a stab at cancer; oncolytic virus-mediated anti-cancer vaccination strategies AS Aitken, DG Roy, MC Bourgeois-Daigneault Biomedicines 5 (1), 3, 2017 | 44 | 2017 |
Adjuvant oncolytic virotherapy for personalized anti-cancer vaccination DG Roy, K Geoffroy, M Marguerie, ST Khan, NT Martin, J Kmiecik, ... Nature Communications 12 (1), 2626, 2021 | 39 | 2021 |
Immunometabolism in the tumor microenvironment DG Roy, I Kaymak, KS Williams, EH Ma, RG Jones Annual Review of Cancer Biology 5, 137-159, 2021 | 32 | 2021 |
Pre-surgical neoadjuvant oncolytic virotherapy confers protection against rechallenge in a murine model of breast cancer NT Martin, DG Roy, ST Workenhe, DJM van Den Wollenberg, RC Hoeben, ... Scientific Reports 9 (1), 1865, 2019 | 32 | 2019 |
Resistance to two heterologous neurotropic oncolytic viruses, Semliki Forest virus and vaccinia virus, in experimental glioma MJV Vähä-Koskela, F Le Boeuf, C Lemay, N De Silva, JS Diallo, J Cox, ... Journal of Virology 87 (4), 2363-2366, 2013 | 32 | 2013 |
Ex vivo infection of live tissue with oncolytic viruses JS Diallo, D Roy, H Abdelbary, N De Silva, JC Bell JoVE (Journal of Visualized Experiments), e2854, 2011 | 32 | 2011 |