Alessandro Michelucci
Alessandro Michelucci
Luxembourg Institute of Health
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Immune-responsive gene 1 protein links metabolism to immunity by catalyzing itaconic acid production
A Michelucci, T Cordes, J Ghelfi, A Pailot, N Reiling, O Goldmann, T Binz, ...
Proceedings of the National Academy of Sciences 110 (19), 7820-7825, 2013
Characterization of the microglial phenotype under specific pro-inflammatory and anti-inflammatory conditions: effects of oligomeric and fibrillar amyloid-β
A Michelucci, T Heurtaux, L Grandbarbe, E Morga, P Heuschling
Journal of neuroimmunology 210 (1-2), 3-12, 2009
Immunoresponsive gene 1 and itaconate inhibit succinate dehydrogenase to modulate intracellular succinate levels
T Cordes, M Wallace, A Michelucci, AS Divakaruni, SC Sapcariu, C Sousa, ...
Journal of Biological Chemistry 291 (27), 14274-14284, 2016
Stem cell-associated heterogeneity in Glioblastoma results from intrinsic tumor plasticity shaped by the microenvironment
A Dirkse, A Golebiewska, T Buder, PV Nazarov, A Muller, S Poovathingal, ...
Nature communications 10 (1), 1-16, 2019
Itaconic acid: the surprising role of an industrial compound as a mammalian antimicrobial metabolite
T Cordes, A Michelucci, K Hiller
Annual review of nutrition 35, 451-473, 2015
Cellular and molecular characterization of microglia: a unique immune cell population
C Sousa, K Biber, A Michelucci
Frontiers in immunology 8, 198, 2017
Notch signaling modulates the activation of microglial cells
L Grandbarbe, A Michelucci, T Heurtaux, K Hemmer, E Morga, ...
Glia 55 (15), 1519-1530, 2007
The itaconate pathway is a central regulatory node linking innate immune tolerance and trained immunity
J Domínguez-Andrés, B Novakovic, Y Li, BP Scicluna, MS Gresnigt, ...
Cell Metabolism 29 (1), 211-220. e5, 2019
Single‐cell transcriptomics reveals distinct inflammation‐induced microglia signatures
C Sousa, A Golebiewska, SK Poovathingal, T Kaoma, Y Pires‐Afonso, ...
EMBO reports 19 (11), e46171, 2018
Microglial activation depends on beta‐amyloid conformation: role of the formylpeptide receptor 2
T Heurtaux, A Michelucci, S Losciuto, C Gallotti, P Felten, G Dorban, ...
Journal of neurochemistry 114 (2), 576-586, 2010
Jagged1 regulates the activation of astrocytes via modulation of NFκB and JAK/STAT/SOCS pathways
E Morga, L Mouad‐Amazzal, P Felten, T Heurtaux, M Moro, A Michelucci, ...
Glia 57 (16), 1741-1753, 2009
Gene Regulatory Network Inference of Immunoresponsive Gene 1 (IRG1) Identifies Interferon Regulatory Factor 1 (IRF1) as Its Transcriptional Regulator in …
A Tallam, TM Perumal, PM Antony, C Jäger, JV Fritz, L Vallar, R Balling, ...
PLoS One 11 (2), e0149050, 2016
Inflammation promotes a conversion of astrocytes into neural progenitor cells via NF-κB activation
S Gabel, E Koncina, G Dorban, T Heurtaux, C Birck, E Glaab, ...
Molecular neurobiology 53 (8), 5041-5055, 2016
The mouse brain metabolome: region-specific signatures and response to excitotoxic neuronal injury
C Jaeger, E Glaab, A Michelucci, TM Binz, S Koeglsberger, P Garcia, ...
The American Journal of Pathology 185 (6), 1699-1712, 2015
The neurogenic potential of astrocytes is regulated by inflammatory signals
A Michelucci, A Bithell, MJ Burney, CE Johnston, KY Wong, SW Teng, ...
Molecular neurobiology 53 (6), 3724-3739, 2016
Loss of DJ-1 impairs antioxidant response by altered glutamine and serine metabolism
J Meiser, S Delcambre, A Wegner, C Jäger, J Ghelfi, AF d'Herouel, ...
Neurobiology of disease 89, 112-125, 2016
Dual bioactivity of resveratrol fatty alcohols: differentiation of neural stem cells and modulation of neuroinflammation
F Hauss, J Liu, A Michelucci, D Coowar, E Morga, P Heuschling, B Luu
Bioorganic & medicinal chemistry letters 17 (15), 4218-4222, 2007
Revealing and Harnessing Tumour-Associated Microglia/Macrophage Heterogeneity in Glioblastoma
Y Pires-Afonso, SP Niclou, A Michelucci
International Journal of Molecular Sciences 21 (3), 689, 2020
Transcriptomic analyses of primary astrocytes under TNFα treatment
C Birck, E Koncina, T Heurtaux, E Glaab, A Michelucci, P Heuschling, ...
Genomics data 7, 7-11, 2016
Transcriptional and epigenetic mechanisms underlying astrocyte identity
MAS Pavlou, L Grandbarbe, NJ Buckley, SP Niclou, A Michelucci
Progress in neurobiology 174, 36-52, 2019
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