Helene Faustrup Kildegaard
Helene Faustrup Kildegaard
Novo Nordisk
Verified email at faustrup.dk
Cited by
Cited by
RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins
N Mailand, S Bekker-Jensen, H Faustrup, F Melander, J Bartek, C Lukas, ...
Cell 131 (5), 887-900, 2007
Site-specific integration in CHO cells mediated by CRISPR/Cas9 and homology-directed DNA repair pathway
JS Lee, TB Kallehauge, LE Pedersen, HF Kildegaard
Scientific reports 5, 8572, 2015
Accelerating genome editing in CHO cells using CRISPR Cas9 and CRISPy, a web‐based target finding tool
C Ronda, LE Pedersen, HG Hansen, TB Kallehauge, MJ Betenbaugh, ...
Biotechnology and bioengineering 111 (8), 1604-1616, 2014
The emerging CHO systems biology era: harnessing the ‘omics revolution for biotechnology
HF Kildegaard, D Baycin-Hizal, NE Lewis, MJ Betenbaugh
Current opinion in biotechnology 24 (6), 1102-1107, 2013
A Consensus Genome-scale Reconstruction of Chinese Hamster Ovary Cell Metabolism
H Hefzi, KS Ang, M Hanscho, A Bordbar, D Ruckerbauer, M Lakshmanan, ...
Cell Systems 3 (5), 434-443. e8, 2016
USP7 counteracts SCFβTrCP-but not APCCdh1-mediated proteolysis of Claspin
H Faustrup, S Bekker-Jensen, J Bartek, J Lukas, N Mailand
The Journal of cell biology 184 (1), 13-19, 2009
One‐step generation of triple knockout CHO cell lines using CRISPR/Cas9 and fluorescent enrichment
LM Grav, JS Lee, S Gerling, TB Kallehauge, AH Hansen, S Kol, GM Lee, ...
Biotechnology journal 10 (9), 1446-1456, 2015
CRISPR/Cas9‐mediated genome engineering of CHO cell factories: Application and perspectives
JS Lee, LM Grav, NE Lewis, H Faustrup Kildegaard
Biotechnology journal 10 (7), 979-994, 2015
Glycoengineering of Chinese hamster ovary cells for enhanced erythropoietin N‐glycan branching and sialylation
B Yin, Y Gao, C Chung, S Yang, E Blake, MC Stuczynski, J Tang, ...
Biotechnology and bioengineering 112 (11), 2343-2351, 2015
Accelerated homology‐directed targeted integration of transgenes in Chinese hamster ovary cells via CRISPR/Cas9 and fluorescent enrichment
JS Lee, LM Grav, LE Pedersen, GM Lee, HF Kildegaard
Biotechnology and bioengineering 113 (11), 2518-2523, 2016
Cell Factory Engineering
AM Davy, HF Kildegaard, MR Andersen
Cell Systems 4 (3), 262-275, 2017
A Markov chain model for N-linked protein glycosylation–towards a low-parameter tool for model-driven glycoengineering
PN Spahn, AH Hansen, HG Hansen, J Arnsdorf, HF Kildegaard, NE Lewis
Metabolic engineering 33, 52-66, 2016
Glycoprofiling effects of media additives on IgG produced by CHO cells in fed‐batch bioreactors
HF Kildegaard, Y Fan, JW Sen, B Larsen, MR Andersen
Biotechnology and bioengineering 113 (2), 359-366, 2016
Ribosome profiling-guided depletion of an mRNA increases cell growth rate and protein secretion
TB Kallehauge, S Li, LE Pedersen, TK Ha, D Ley, MR Andersen, ...
Scientific Reports 7, 40388, 2017
Improving the secretory capacity of Chinese hamster ovary cells by ectopic expression of effector genes: Lessons learned and future directions
HG Hansen, N Pristovšek, HF Kildegaard, GM Lee
Biotechnology advances 35 (1), 64-76, 2017
Impact of CHO metabolism on cell growth and protein production: an overview of toxic and inhibiting metabolites and nutrients
S Pereira, HF Kildegaard, MR Andersen
Biotechnology journal 13 (3), 1700499, 2018
Versatile microscale screening platform for improving recombinant protein productivity in Chinese hamster ovary cells
HG Hansen, CN Nilsson, AM Lund, S Kol, LM Grav, M Lundqvist, ...
Scientific reports 5, 18016, 2015
A Versatile System for USER Cloning-Based Assembly of Expression Vectors for Mammalian Cell Engineering
AM Lund, HF Kildegaard, MBK Petersen, J Rank, BG Hansen, ...
PloS one 9 (5), e96693, 2014
Enhanced Genome Editing Tools For Multi‐Gene Deletion Knock‐Out Approaches Using Paired CRISPR sgRNAs in CHO Cells
V Schmieder, N Bydlinski, R Strasser, M Baumann, HF Kildegaard, ...
Biotechnology journal 13 (3), 1700211, 2018
Toward genome-scale models of the Chinese hamster ovary cells: incentives, status and perspectives
CS Kaas, Y Fan, D Weilguny, C Kristensen, HF Kildegaard, MR Andersen
Pharmaceutical Bioprocessing 2 (5), 437-448, 2014
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