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Stephen Hare
Stephen Hare
School of Life Sciences, University of Sussex
Verified email at sussex.ac.uk - Homepage
Title
Cited by
Cited by
Year
Retroviral intasome assembly and inhibition of DNA strand transfer
S Hare, SS Gupta, E Valkov, A Engelman, P Cherepanov
Nature 464 (7286), 232-236, 2010
7922010
The mechanism of retroviral integration from X-ray structures of its key intermediates
GN Maertens, S Hare, P Cherepanov
Nature 468 (7321), 326-329, 2010
3612010
Molecular mechanisms of retroviral integrase inhibition and the evolution of viral resistance
S Hare, AM Vos, RF Clayton, JW Thuring, MD Cummings, P Cherepanov
Proceedings of the National Academy of Sciences 107 (46), 20057-20062, 2010
3552010
Structural and functional analyses of the second-generation integrase strand transfer inhibitor dolutegravir (S/GSK1349572)
S Hare, SJ Smith, M Metifiot, A Jaxa-Chamiec, Y Pommier, SH Hughes, ...
Molecular pharmacology 80 (4), 565-572, 2011
3132011
A Salmonella toxin promotes persister formation through acetylation of tRNA
AM Cheverton, B Gollan, M Przydacz, CT Wong, A Mylona, SA Hare, ...
Molecular cell 63 (1), 86-96, 2016
2222016
Structure-based modeling of the functional HIV-1 intasome and its inhibition
L Krishnan, X Li, HL Naraharisetty, S Hare, P Cherepanov, A Engelman
Proceedings of the National Academy of Sciences 107 (36), 15910-15915, 2010
2222010
A novel co-crystal structure affords the design of gain-of-function lentiviral integrase mutants in the presence of modified PSIP1/LEDGF/p75
S Hare, MC Shun, SS Gupta, E Valkov, A Engelman, P Cherepanov
PLoS pathogens 5 (1), e1000259, 2009
1802009
3′‐Processing and strand transfer catalysed by retroviral integrase in crystallo
S Hare, GN Maertens, P Cherepanov
The EMBO journal 31 (13), 3020-3028, 2012
1672012
Structural basis for retroviral integration into nucleosomes
DP Maskell, L Renault, E Serrao, P Lesbats, R Matadeen, S Hare, ...
Nature 523 (7560), 366-369, 2015
1542015
Functional and structural characterization of the integrase from the prototype foamy virus
E Valkov, SS Gupta, S Hare, A Helander, P Roversi, M McClure, ...
Nucleic acids research 37 (1), 243-255, 2009
1512009
Structural basis for nuclear import of splicing factors by human Transportin 3
GN Maertens, NJ Cook, W Wang, S Hare, SS Gupta, I Öztop, KE Lee, ...
Proceedings of the National Academy of Sciences 111 (7), 2728-2733, 2014
1462014
Structural basis for functional tetramerization of lentiviral integrase
S Hare, F Di Nunzio, A Labeja, J Wang, A Engelman, P Cherepanov
PLoS pathogens 5 (7), e1000515, 2009
1452009
Structural insights into the retroviral DNA integration apparatus
P Cherepanov, GN Maertens, S Hare
Current opinion in structural biology 21 (2), 249-256, 2011
1352011
Activity of acetyltransferase toxins involved in Salmonella persister formation during macrophage infection
JA Rycroft, B Gollan, GJ Grabe, A Hall, AM Cheverton, G Larrouy-Maumus, ...
Nature Communications 9 (1), 1993, 2018
902018
A large domain swap in the VirB11 ATPase of Brucella suis leaves the hexameric assembly intact
S Hare, R Bayliss, C Baron, G Waksman
Journal of molecular biology 360 (1), 56-66, 2006
822006
A new class of hybrid secretion system is employed in Pseudomonas amyloid biogenesis
SL Rouse, WJ Hawthorne, JL Berry, DS Chorev, SA Ionescu, S Lambert, ...
Nature communications 8 (1), 263, 2017
572017
The Salmonella effector SpvD is a cysteine hydrolase with a serovar-specific polymorphism influencing catalytic activity, suppression of immune responses, and bacterial virulence
GJ Grabe, Y Zhang, M Przydacz, N Rolhion, Y Yang, JN Pruneda, ...
Journal of Biological Chemistry 291 (50), 25853-25863, 2016
472016
Activities, Crystal Structures, and Molecular Dynamics of Dihydro-1H-isoindole Derivatives, Inhibitors of HIV-1 Integrase
M Métifiot, K Maddali, BC Johnson, S Hare, SJ Smith, XZ Zhao, ...
ACS chemical biology 8 (1), 209-217, 2013
462013
Identification, structure and mode of action of a new regulator of the Helicobacter pylori HP0525 ATPase
S Hare, W Fischer, R Williams, L Terradot, R Bayliss, R Haas, G Waksman
The EMBO Journal 26 (23), 4926-4934, 2007
442007
Structural analysis of haemoglobin binding by HpuA from the Neisseriaceae family
CT Wong, Y Xu, A Gupta, JA Garnett, SJ Matthews, SA Hare
Nature communications 6 (1), 10172, 2015
372015
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