Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia CM Metallo, PA Gameiro, EL Bell, KR Mattaini, J Yang, K Hiller, ... Nature 481 (7381), 380-384, 2012 | 1300 | 2012 |
JCat: a novel tool to adapt codon usage of a target gene to its potential expression host A Grote, K Hiller, M Scheer, R Münch, B Nörtemann, DC Hempel, D Jahn Nucleic acids research 33 (suppl 2), W526-W531, 2005 | 588 | 2005 |
Immune-responsive gene 1 protein links metabolism to immunity by catalyzing itaconic acid production A Michelucci, T Cordes, J Ghelfi, A Pailot, N Reiling, O Goldmann, T Binz, ... Proceedings of the National Academy of Sciences 110 (19), 7820-7825, 2013 | 482 | 2013 |
PrediSi: prediction of signal peptides and their cleavage positions K Hiller, A Grote, M Scheer, R Münch, D Jahn Nucleic acids research 32 (suppl 2), W375-W379, 2004 | 457 | 2004 |
Complexity of dopamine metabolism J Meiser, D Weindl, K Hiller Cell Communication and Signaling 11 (1), 2013 | 414 | 2013 |
Oncogenic K-Ras decouples glucose and glutamine metabolism to support cancer cell growth D Gaglio, CM Metallo, PA Gameiro, K Hiller, LS Danna, C Balestrieri, ... Molecular systems biology 7 (1), 2011 | 398 | 2011 |
Virtual Footprint and PRODORIC: an integrative framework for regulon prediction in prokaryotes R Münch, K Hiller, A Grote, M Scheer, J Klein, M Schobert, D Jahn Bioinformatics 21 (22), 4187-4189, 2005 | 397 | 2005 |
A roadmap for interpreting 13 C metabolite labeling patterns from cells JM Buescher, MR Antoniewicz, LG Boros, SC Burgess, H Brunengraber, ... Current opinion in biotechnology 34, 189-201, 2015 | 371 | 2015 |
MetaboliteDetector: comprehensive analysis tool for targeted and nontargeted GC/MS based metabolome analysis K Hiller, J Hangebrauk, C Jäger, J Spura, K Schreiber, D Schomburg Anal. Chem 81, 3429-3439, 2009 | 330 | 2009 |
PRODORIC: prokaryotic database of gene regulation R Münch, K Hiller, H Barg, D Heldt, S Linz, E Wingender, D Jahn Nucleic acids research 31 (1), 266-269, 2003 | 264 | 2003 |
Immunoresponsive gene 1 and itaconate inhibit succinate dehydrogenase to modulate intracellular succinate levels T Cordes, M Wallace, A Michelucci, AS Divakaruni, SC Sapcariu, C Sousa, ... Journal of Biological Chemistry 291 (27), 14274-14284, 2016 | 176 | 2016 |
Glutathione Primes T Cell Metabolism for Inflammation TW Mak, M Grusdat, GS Duncan, C Dostert, Y Nonnenmacher, M Cox, ... Immunity 46 (4), 675-689, 2017 | 157 | 2017 |
Nontargeted elucidation of metabolic pathways using stable-isotope tracers and mass spectrometry K Hiller, CM Metallo, JK Kelleher, G Stephanopoulos Analytical chemistry 82 (15), 6621-6628, 2010 | 116 | 2010 |
BCAT1 restricts αKG levels in AML stem cells leading to IDHmut-like DNA hypermethylation S Raffel, M Falcone, N Kneisel, J Hansson, W Wang, C Lutz, L Bullinger, ... Nature 551 (7680), 384-388, 2017 | 115 | 2017 |
Pro-inflammatory macrophages sustain pyruvate oxidation through pyruvate dehydrogenase for the synthesis of itaconate and to enable cytokine expression J Meiser, L Krämer, SC Sapcariu, N Battello, J Ghelfi, ... Journal of Biological Chemistry 291 (8), 3932-3946, 2015 | 115 | 2015 |
PGC-1α supports glutamine metabolism in breast cancer S McGuirk, SP Gravel, G Deblois, DJ Papadopoli, B Faubert, A Wegner, ... Cancer & metabolism 1 (1), 22, 2013 | 111 | 2013 |
Itaconic Acid: The Surprising Role of an Industrial Compound as a Mammalian Antimicrobial Metabolite T Cordes, A Michelucci, K Hiller Annual Review of Nutrition, 2015 | 96 | 2015 |
Profiling metabolic networks to study cancer metabolism K Hiller, CM Metallo Current opinion in biotechnology 24 (1), 60-68, 2013 | 92 | 2013 |
JVirGel: calculation of virtual two-dimensional protein gels K Hiller, M Schobert, C Hundertmark, D Jahn, R Münch Nucleic acids research 31 (13), 3862-3865, 2003 | 90 | 2003 |
Simultaneous extraction of proteins and metabolites from cells in culture SC Sapcariu, T Kanashova, D Weindl, J Ghelfi, G Dittmar, K Hiller MethodsX 1, 74-80, 2014 | 88 | 2014 |