Ian Winters
Ian Winters
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Pancreatic cancer modeling using retrograde viral vector delivery and in vivo CRISPR/Cas9-mediated somatic genome editing
SH Chiou, IP Winters, J Wang, S Naranjo, C Dudgeon, FB Tamburini, ...
Genes & development 29 (14), 1576-1585, 2015
Mapping the in vivo fitness landscape of lung adenocarcinoma tumor suppression in mice
ZN Rogers, CD McFarland, IP Winters, JA Seoane, JJ Brady, S Yoon, ...
Nature genetics 50 (4), 483-486, 2018
A quantitative and multiplexed approach to uncover the fitness landscape of tumor suppression in vivo
ZN Rogers, CD McFarland, IP Winters, S Naranjo, CH Chuang, D Petrov, ...
Nature methods 14 (7), 737-742, 2017
Multiplexed in vivo homology-directed repair and tumor barcoding enables parallel quantification of Kras variant oncogenicity
IP Winters, SH Chiou, NK Paulk, CD McFarland, PV Lalgudi, RK Ma, ...
Nature communications 8 (1), 2053, 2017
An LKB1–SIK axis suppresses lung tumor growth and controls differentiation
CW Murray, JJ Brady, MK Tsai, C Li, IP Winters, R Tang, L Andrejka, ...
Cancer discovery 9 (11), 1590-1605, 2019
RNA interference in marine and freshwater sponges: actin knockdown in Tethya wilhelma and Ephydatia muelleriby ingested dsRNA expressing bacteria
AS Rivera, JU Hammel, KM Haen, ES Danka, B Cieniewicz, IP Winters, ...
BMC biotechnology 11, 1-15, 2011
Towards quantitative and multiplexed in vivo functional cancer genomics
IP Winters, CW Murray, MM Winslow
Nature Reviews Genetics 19 (12), 741-755, 2018
Zmat3 is a key splicing regulator in the p53 tumor suppression program
KT Bieging-Rolett, AM Kaiser, DW Morgens, AM Boutelle, JA Seoane, ...
Molecular cell 80 (3), 452-469. e9, 2020
The evolution and function of the Pax/S ix regulatory network in sponges
A Rivera, I Winters, A Rued, S Ding, D Posfai, B Cieniewicz, K Cameron, ...
Evolution & Development 15 (3), 186-196, 2013
Tumor suppressor activity of Selenbp1, a direct Nkx2-1 target, in lung adenocarcinoma
DR Caswell, CH Chuang, RK Ma, IP Winters, EL Snyder, MM Winslow
Molecular Cancer Research 16 (11), 1737-1749, 2018
Quantitative In Vivo Analyses Reveal a Complex Pharmacogenomic Landscape in Lung Adenocarcinoma
C Li, WY Lin, H Rizvi, H Cai, CD McFarland, ZN Rogers, M Yousefi, ...
Cancer research 81 (17), 4570-4580, 2021
An LKB1-SIK axis suppresses lung tumor growth and controls differentiation. Cancer Discov. 2019; 9: 1590–1605. doi: 10.1158/2159-8290
CW Murray, JJ Brady, MK Tsai, C Li, IP Winters, R Tang, L Andrejka, ...
CD-18-1237.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0
Oncogenic context shapes the fitness landscape of tumor suppression
LM Blair, JM Juan, L Sebastian, VB Tran, W Nie, GD Wall, M Gerceker, ...
Nature Communications 14 (1), 6422, 2023
Compositions and methods for multiplexed quantitative analysis of cell lineages
MM Winslow, D Petrov, IP Winters, C McFarland, ZN Rogers
US Patent 10,801,021, 2020
21 CRISPR/Cas9-based In Vivo Models of Cancer
PV Lalgudi, MM Winslow, IP Winters
Genome editing and engineering: from TALENs, ZFNs and CRISPRs to molecular …, 2018
Biomarkers for predicting responsiveness to shp2 inhibitor therapy
IP Winters, JBM Juan, MJ Rosen, MM Winslow, DA Petrov, GD Wall
US Patent App. 18/161,664, 2023
An in vivo pharmacogenomics platform replicates and extends biomarkers of therapy response identified via causal inference analysis of clinical data
D Amar, E Scott, IP Winters, GD Wall, DA Petrov, MM Winslow, J Juan, ...
Cancer Research 83 (7_Supplement), 5723-5723, 2023
Tumor suppressor genotype dramatically impacts lung cancer response to KRAS G12C inhibitors in vivo
PJ McMurdie, IP Winters, LM Blair, L Sebastian, V Tran, G Grenot, ...
Cancer Research 83 (7_Supplement), 2789-2789, 2023
Analysis of 30 million tumor time course reveals that inactivating tumor suppressors produces complex gene-specific, time-dependent growth dynamics
AL Severson, J Juan, L Sebastian, V Tran, W Nie, I Lai, GD Wall, ...
Cancer Research 83 (7_Supplement), 11-11, 2023
Compositions and methods for multiplexed quantitative analysis of cell lineages
M Winslow, D Petrov, I Winters, C McFarland, Z Rogers
US Patent App. 17/281,919, 2022
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