| Overexpression of glyoxalase-I reduces hyperglycemia-induced levels of advanced glycation end products and oxidative stress in diabetic rats O Brouwers, PM Niessen, I Ferreira, T Miyata, PG Scheffer, T Teerlink, ... Journal of Biological Chemistry 286 (2), 1374-1380, 2011 | 249 | 2011 |
| Hyperglycaemia-induced impairment of endothelium-dependent vasorelaxation in rat mesenteric arteries is mediated by intracellular methylglyoxal levels in a pathway dependent on … O Brouwers, PM Niessen, G Haenen, T Miyata, M Brownlee, ... Diabetologia 53, 989-1000, 2010 | 210 | 2010 |
| Protection against methylglyoxal-derived AGEs by regulation of glyoxalase 1 prevents retinal neuroglial and vasodegenerative pathology AK Berner, O Brouwers, R Pringle, I Klaassen, L Colhoun, C McVicar, ... Diabetologia 55, 845-854, 2012 | 169 | 2012 |
| Glyoxalase-1 overexpression reduces endothelial dysfunction and attenuates early renal impairment in a rat model of diabetes O Brouwers, PMG Niessen, T Miyata, JA Østergaard, A Flyvbjerg, ... Diabetologia 57, 224-235, 2014 | 151 | 2014 |
| Delayed intervention with Pyridoxamine improves metabolic function and prevents adipose tissue inflammation and insulin resistance in high-fat diet–induced obese mice DE Maessen, O Brouwers, KH Gaens, K Wouters, JP Cleutjens, ... Diabetes 65 (4), 956-966, 2016 | 70 | 2016 |
| Hypertension is a conditional factor for the development of cardiac hypertrophy in type 2 diabetic mice M van Bilsen, A Daniels, O Brouwers, BJA Janssen, WJA Derks, ... PLoS One 9 (1), e85078, 2014 | 49 | 2014 |
| Modulation of insulin action by advanced glycation endproducts: a new player in the field CG Schalkwijk, O Brouwers, CDA Stehouwer Hormone and metabolic research 40 (09), 614-619, 2008 | 49 | 2008 |
| Mild oxidative damage in the diabetic rat heart is attenuated by glyoxalase-1 overexpression O Brouwers, JMJ de Vos-Houben, PMG Niessen, T Miyata, ... International journal of molecular sciences 14 (8), 15724-15739, 2013 | 35 | 2013 |
| Polymorphisms in glyoxalase 1 gene are not associated with vascular complications: the Hoorn and CoDAM studies L Engelen, I Ferreira, O Brouwers, RMA Henry, JM Dekker, G Nijpels, ... Journal of hypertension 27 (7), 1399-1403, 2009 | 35 | 2009 |
| Glyoxalase 1 overexpression does not affect atherosclerotic lesion size and severity in ApoE−/− mice with or without diabetes NMJ Hanssen, O Brouwers, MJ Gijbels, K Wouters, E Wijnands, ... Cardiovascular research 104 (1), 160-170, 2014 | 24 | 2014 |
| Methylglyoxal and Methylglyoxal‐arginine Adducts Do Not Directly Inhibit Endothelial Nitric Oxide Synthase O Brouwers, T Teerlink, J Van Bezu, R Barto, CDA Stehouwer, ... Annals of the New York Academy of Sciences 1126 (1), 231-234, 2008 | 20 | 2008 |
| Glyoxalase-1 overexpression partially prevents diabetes-induced impaired arteriogenesis in a rat hindlimb ligation model O Brouwers, L Yu, P Niessen, J Slenter, K Jaspers, A Wagenaar, M Post, ... Glycoconjugate Journal 33, 627-630, 2016 | 11 | 2016 |
| Glyoxalase-1 overexpression reduces body weight and adipokine expression, and improves insulin sensitivity in high-fat diet-induced obese mice D Maessen, O Brouwers, T Miyata, C Stehouwer, C Schalkwijk Diabetologia 57, S290-S291, 2014 | 10 | 2014 |
| The role of methylglyoxal in hyperglycemia-induced impairments of vasoreactivity in rat saphenous artery MS Ruiter, JM Van Golde, NC Schaper, CD Stehouwer, MS Huijberts Reactivity, recruitment and remodeling of collateral arteries in diabetes, 83-98, 2012 | 3 | 2012 |
| Overexpression of glyoxalase-I improves vascular function in a rat model of diabetes O Brouwers, PMG Niessen, T Miyata, T Teerlink, BJ Janssen, ... Diabetologia 53, 989-1000, 2010 | 2 | 2010 |
| Glyoxalase-I overexpression improves endothelial dysfunction and attenuates renal impairment in diabetic rats O Brouwers, P Niessen, T Miyata, M Brownlee, J De Mey, C Stehouwer, ... INTRACELLULAR GLYCATION AND ENDOTHELIAL DYSFUNCTION; ROLE OF METHYLGLYOXAL, 87, 2011 | 1 | 2011 |
| Methylglyoxal-modified DNA is increased in urine of type 1 diabetic rats and correlates with early diabetic kidney disease JLJ Scheijen, NMJ Hanssen, O Brouwers, CDA Stehouwer, ... DIABETOLOGIA 62, S496-S496, 2019 | | 2019 |
| PS1-6. Pyridoxamine improves adiposity and insulin resistance in high-fed diet induced obese mice K Gaens, O Brouwers, T Miyata, C Stehouwer, C Schalkwijk Nederlands Tijdschrift voor Diabetologie 11, 145-146, 2013 | | 2013 |
| Delayed intervention with pyridoxamine improves metabolic and vascular function in high-fat diet-induced obese mice O Brouwers, K Gaens, T Miyata, BJ Janssen, JGR De Mey, ... DIABETOLOGIA 56, S54-S55, 2013 | | 2013 |
| Mild Oxidative Damage in the Diabetic Rat Heart Is Attenuated by Glyoxalase-1 Overexpression CG Schalkwijk, CDA Stehouwer, G Hageman, BJA Janssen, ... | | 2013 |
