| Late interleukin-6 escalates T follicular helper cell responses and controls a chronic viral infection JA Harker, GM Lewis, L Mack, EI Zuniga Science 334 (6057), 825-829, 2011 | 375 | 2011 |
| Organ specificity, colonization and clearance dynamics in vivo following oral challenges with the murine pathogen Citrobacter rodentium S Wiles, S Clare, J Harker, A Huett, D Young, G Dougan, G Frankel Cellular microbiology 6 (10), 963-972, 2004 | 273 | 2004 |
| Alveolar macrophages are a major determinant of early responses to viral lung infection but do not influence subsequent disease development PK Pribul, J Harker, B Wang, H Wang, JS Tregoning, J Schwarze, ... Journal of virology 82 (9), 4441-4448, 2008 | 250 | 2008 |
| CD25+ natural regulatory T cells are critical in limiting innate and adaptive immunity and resolving disease following respiratory syncytial virus infection DCP Lee, JAE Harker, JS Tregoning, SF Atabani, C Johansson, ... Journal of virology 84 (17), 8790-8798, 2010 | 181 | 2010 |
| Glycogen Synthase Kinase 3 Inactivation Drives T-bet-Mediated Downregulation of Co-receptor PD-1 to Enhance CD8+ Cytolytic T Cell Responses A Taylor, JA Harker, K Chanthong, PG Stevenson, EI Zuniga, CE Rudd Immunity 44 (2), 274-286, 2016 | 167 | 2016 |
| C1q restrains autoimmunity and viral infection by regulating CD8+ T cell metabolism GS Ling, G Crawford, N Buang, I Bartok, K Tian, NM Thielens, I Bally, ... Science 360 (6388), 558-563, 2018 | 152 | 2018 |
| Innate and adaptive immune regulation during chronic viral infections EI Zuniga, M Macal, GM Lewis, JA Harker Annual review of virology 2, 573-597, 2015 | 150 | 2015 |
| Early IL-6 signalling promotes IL-27 dependent maturation of regulatory T cells in the lungs and resolution of viral immunopathology CJ Pyle, FI Uwadiae, DP Swieboda, JA Harker PLoS pathogens 13 (9), e1006640, 2017 | 135 | 2017 |
| The role of T cells in the enhancement of respiratory syncytial virus infection severity during adult reinfection of neonatally sensitized mice JS Tregoning, Y Yamaguchi, J Harker, B Wang, PJM Openshaw Journal of virology 82 (8), 4115-4124, 2008 | 129 | 2008 |
| Immuno-proteomic profiling reveals aberrant immune cell regulation in the airways of individuals with ongoing post-COVID-19 respiratory disease B Vijayakumar, K Boustani, PP Ogger, A Papadaki, J Tonkin, CM Orton, ... Immunity, 2022 | 106 | 2022 |
| T follicular helper (Tfh) cells in normal immune responses and in allergic disorders G Varricchi, J Harker, F Borriello, G Marone, SR Durham, MH Shamji Allergy 71 (8), 1086-1094, 2016 | 102 | 2016 |
| Plasmacytoid dendritic cells are productively infected and activated through TLR-7 early after arenavirus infection M Macal, GM Lewis, S Kunz, R Flavell, JA Harker, EI Zúñiga Cell host & microbe 11 (6), 617-630, 2012 | 95 | 2012 |
| Monocarboxylate transporter 1 blockade with AZD3965 inhibits lipid biosynthesis and increases tumour immune cell infiltration M Beloueche-Babari, T Casals Galobart, T Delgado-Goni, S Wantuch, ... British journal of cancer 122 (6), 895-903, 2020 | 83 | 2020 |
| Cell-intrinsic IL-27 and gp130 cytokine receptor signaling regulates virus-specific CD4+ T cell responses and viral control during chronic infection JA Harker, A Dolgoter, EI Zuniga Immunity 39 (3), 548-559, 2013 | 83 | 2013 |
| RSV-induced bronchial epithelial cell PD-L1 expression inhibits CD8+ T cell nonspecific antiviral activity AG Telcian, V Laza-Stanca, MR Edwards, JA Harker, H Wang, NW Bartlett, ... Journal of Infectious Diseases 203 (1), 85-94, 2011 | 82 | 2011 |
| Follicular helper-T cells restore CD8+-dependent antitumor immunity and anti-PD-L1/PD-1 efficacy J Niogret, H Berger, C Rebe, R Mary, E Ballot, C Truntzer, M Thibaudin, ... Journal for immunotherapy of cancer 9 (6), 2021 | 78 | 2021 |
| Neutrophils drive alveolar macrophage IL-1β release during respiratory viral infection T Peiró, DF Patel, S Akthar, LG Gregory, CJ Pyle, JA Harker, MA Birrell, ... Thorax 73 (6), 546-556, 2018 | 78 | 2018 |
| Sustained T follicular helper cell response is essential for control of chronic viral infection U Greczmiel, NJ Kräutler, A Pedrioli, I Bartsch, P Agnellini, G Bedenikovic, ... Science immunology 2 (18), eaam8686, 2017 | 78 | 2017 |
| Interleukin 18 coexpression during respiratory syncytial virus infection results in enhanced disease mediated by natural killer cells JA Harker, A Godlee, JL Wahlsten, DCP Lee, LG Thorne, D Sawant, ... Journal of virology 84 (8), 4073-4082, 2010 | 71 | 2010 |
| Delayed sequelae of neonatal respiratory syncytial virus infection are dependent on cells of the innate immune system JA Harker, Y Yamaguchi, FJ Culley, JS Tregoning, PJM Openshaw Journal of virology 88 (1), 604-611, 2014 | 51 | 2014 |
