| Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth JB Baell, DJ Leaver, SJ Hermans, GL Kelly, MS Brennan, NL Downer, ... Nature 560 (7717), 253-257, 2018 | 207 | 2018 |
| The neuropeptide VIP confers anticipatory mucosal immunity by regulating ILC3 activity C Seillet, K Luong, J Tellier, N Jacquelot, RD Shen, P Hickey, VC Wimmer, ... Nature immunology 21 (2), 168-177, 2020 | 150 | 2020 |
| The TNF receptor superfamily-NF-κB axis is critical to maintain effector regulatory T cells in lymphoid and non-lymphoid tissues A Vasanthakumar, Y Liao, P Teh, MF Pascutti, AE Oja, AL Garnham, ... Cell reports 20 (12), 2906-2920, 2017 | 132 | 2017 |
| SIDT2 transports extracellular dsRNA into the cytoplasm for innate immune recognition TA Nguyen, BRC Smith, MD Tate, GT Belz, MH Barrios, KD Elgass, ... Immunity 47 (3), 498-509. e6, 2017 | 126 | 2017 |
| An aspartyl protease defines a novel pathway for export of Toxoplasma proteins into the host cell MJ Coffey, BE Sleebs, AD Uboldi, A Garnham, M Franco, ND Marino, ... Elife 4, e10809, 2015 | 118 | 2015 |
| Flexible usage and interconnectivity of diverse cell death pathways protect against intracellular infection M Doerflinger, Y Deng, P Whitney, R Salvamoser, S Engel, AJ Kueh, L Tai, ... Immunity 53 (3), 533-547. e7, 2020 | 109 | 2020 |
| Attenuation of TCR-induced transcription by Bach2 controls regulatory T cell differentiation and homeostasis T Sidwell, Y Liao, AL Garnham, A Vasanthakumar, R Gloury, J Blume, ... Nature communications 11 (1), 252, 2020 | 71 | 2020 |
| Glutaminase inhibition impairs CD8 T cell activation in STK11-/Lkb1-deficient lung cancer SA Best, PM Gubser, S Sethumadhavan, A Kersbergen, YLN Abril, ... Cell Metabolism 34 (6), 874-887. e6, 2022 | 60 | 2022 |
| Extracellular vesicles from early stage Plasmodium falciparum‐infected red blood cells contain PfEMP1 and induce transcriptional changes in human monocytes NG Sampaio, SJ Emery, AL Garnham, QY Tan, X Sisquella, MA Pimentel, ... Cellular Microbiology 20 (5), e12822, 2018 | 60 | 2018 |
| Responses of the Differentiated Intestinal Epithelial Cell Line Caco-2 to Infection With the Giardia intestinalis GS Isolate SY Ma'Ayeh, L Knörr, K Sköld, A Garnham, BRE Ansell, AR Jex, SG Svärd Frontiers in cellular and infection microbiology 8, 244, 2018 | 41 | 2018 |
| Acute myeloid leukemia requires Hhex to enable PRC2-mediated epigenetic repression of Cdkn2a BJ Shields, JT Jackson, D Metcalf, W Shi, Q Huang, AL Garnham, ... Genes & development 30 (1), 78-91, 2016 | 40 | 2016 |
| Dysregulated IL-1β-GM-CSF axis in acute rheumatic fever that is limited by hydroxychloroquine ML Kim, WJ Martin, G Minigo, JL Keeble, AL Garnham, G Pacini, ... Circulation 138 (23), 2648-2661, 2018 | 39 | 2018 |
| PHF6 regulates hematopoietic stem and progenitor cells and its loss synergizes with expression of TLX3 to cause leukemia HM McRae, AL Garnham, Y Hu, MT Witkowski, MA Corbett, MP Dixon, ... Blood, The Journal of the American Society of Hematology 133 (16), 1729-1741, 2019 | 38 | 2019 |
| Multi-level remodelling of chromatin underlying activation of human T cells NG Bediaga, HD Coughlan, TM Johanson, AL Garnham, G Naselli, ... Scientific reports 11 (1), 528, 2021 | 35 | 2021 |
| Single-cell multiomics reveal the scale of multilayered adaptations enabling CLL relapse during venetoclax therapy R Thijssen, L Tian, MA Anderson, C Flensburg, A Jarratt, AL Garnham, ... Blood, The Journal of the American Society of Hematology 140 (20), 2127-2141, 2022 | 33 | 2022 |
| Necroptosis is dispensable for the development of inflammation-associated or sporadic colon cancer in mice S Alvarez-Diaz, A Preaudet, AL Samson, PM Nguyen, KY Fung, ... Cell Death & Differentiation 28 (5), 1466-1476, 2021 | 32 | 2021 |
| Impaired social behaviour and molecular mediators of associated neural circuits during chronic Toxoplasma gondii infection in female mice S Tyebji, S Seizova, AL Garnham, AJ Hannan, CJ Tonkin Brain, behavior, and immunity 80, 88-108, 2019 | 30 | 2019 |
| The histone lysine acetyltransferase HBO1 (KAT7) regulates hematopoietic stem cell quiescence and self-renewal Y Yang, AJ Kueh, ZL Grant, W Abeysekera, AL Garnham, S Wilcox, ... Blood, The Journal of the American Society of Hematology 139 (6), 845-858, 2022 | 28 | 2022 |
| Design, synthesis, and biological activity of 1, 2, 3-triazolobenzodiazepine BET bromodomain inhibitors PP Sharp, JM Garnier, T Hatfaludi, Z Xu, D Segal, KE Jarman, H Jousset, ... ACS Medicinal Chemistry Letters 8 (12), 1298-1303, 2017 | 28 | 2017 |
| MOZ directs the distal-less homeobox gene expression program during craniofacial development HK Vanyai, A Garnham, RE May, HM McRae, C Collin, S Wilcox, ... Development 146 (14), dev175042, 2019 | 22 | 2019 |
