| Unbiased detection of off-target cleavage by CRISPR-Cas9 and TALENs using integrase-defective lentiviral vectors X Wang, Y Wang, X Wu, J Wang, Y Wang, Z Qiu, T Chang, H Huang, ... Nature biotechnology 33 (2), 175-178, 2015 | 509 | 2015 |
| Lariat structures are in vivo intermediates in yeast pre-mRNA splicing H Domdey, B Apostol, RJ Lin, A Newman, E Brody, J Abelson Cell 39 (3), 611-621, 1984 | 420 | 1984 |
| Yeast mRNA splicing in vitro. RJ Lin, AJ Newman, SC Cheng, J Abelson Journal of Biological Chemistry 260 (27), 14780-14792, 1985 | 367 | 1985 |
| Metal-ion coordination by U6 small nuclear RNA contributes to catalysis in the spliceosome SL Yean, G Wuenschell, J Termini, RJ Lin Nature 408 (6814), 881-884, 2000 | 302 | 2000 |
| DExD/H-box proteins and their partners: helping RNA helicases unwind E Silverman, G Edwalds-Gilbert, RJ Lin Gene 312, 1-16, 2003 | 267 | 2003 |
| Spliceosome activation by PRP2 ATPase prior to the first transesterification reaction of pre-mRNA splicing SH Kim, RJ Lin Molecular and cellular biology 16 (12), 6810-6819, 1996 | 195 | 1996 |
| The purified yeast pre‐mRNA splicing factor PRP2 is an RNA‐dependent NTPase. SH Kim, J Smith, A Claude, RJ Lin The EMBO journal 11 (6), 2319-2326, 1992 | 189 | 1992 |
| A repetitive DNA sequence, rhs, responsible for duplications within the Escherichia coli K-12 chromosome RJ Lin, M Capage, CW Hill Journal of molecular biology 177 (1), 1-18, 1984 | 174 | 1984 |
| Splicing of yeast nuclear pre-mRNA in vitro requires a functional 40S spliceosome and several extrinsic factors. RJ Lin, AJ Lustig, J Abelson Genes & development 1 (1), 7-18, 1987 | 151 | 1987 |
| The yeast RNA gene products are essential for mRNA splicing in vitro AJ Lustig, RJ Lin, J Abelson Cell 47 (6), 953-963, 1986 | 149 | 1986 |
| U4 small nuclear RNA dissociates from a yeast spliceosome and does not participate in the subsequent splicing reaction SL Yean, RJ Lin Molecular and Cellular Biology 11 (11), 5571-5577, 1991 | 147 | 1991 |
| Interaction between a G-patch protein and a spliceosomal DEXD/H-box ATPase that is critical for splicing EJ Silverman, A Maeda, J Wei, P Smith, JD Beggs, RJ Lin Molecular and cellular biology 24 (23), 10101-10110, 2004 | 133 | 2004 |
| The yeast PRP2 protein, a putative RNA-dependent ATPase, shares extensive sequence homology with two other pre-mRNA splicing factors. JH Chen, RJ Lin Nucleic acids research 18 (21), 6447, 1990 | 127 | 1990 |
| Cell type and culture condition–dependent alternative splicing in human breast cancer cells revealed by splicing-sensitive microarrays C Li, M Kato, L Shiue, JE Shively, M Ares Jr, RJ Lin Cancer Research 66 (4), 1990-1999, 2006 | 112 | 2006 |
| Brief report: phenotypic rescue of induced pluripotent stem cell-derived motoneurons of a spinal muscular atrophy patient T Chang, W Zheng, W Tsark, S Bates, H Huang, RJ Lin, JK Yee Stem cells 29 (12), 2090-2093, 2011 | 109 | 2011 |
| Pre-mRNA splicing within an assembled yeast spliceosome requires an RNA-dependent ATPase and ATP hydrolysis. SH Kim, RJ Lin Proceedings of the National Academy of Sciences 90 (3), 888-892, 1993 | 86 | 1993 |
| Fission yeast mitotic regulator Dsk1 is an SR protein-specific kinase Z Tang, M Yanagida, RJ Lin Journal of Biological Chemistry 273 (10), 5963-5969, 1998 | 63 | 1998 |
| MicroRNA-focused CRISPR-Cas9 library screen reveals fitness-associated miRNAs JS Kurata, RJ Lin Rna 24 (7), 966-981, 2018 | 59 | 2018 |
| MicroRNA and HER2-overexpressing cancer S Emily Wang, RJ Lin Microrna 2 (2), 137-147, 2013 | 47 | 2013 |
| Preparation and fractionation of yeast splicing extract SC Cheng, A Newman, RJ Lin, GD McFarland, JN Abelson Methods in enzymology 181, 89-96, 1990 | 47 | 1990 |
