Anthony Bradley
Anthony Bradley
Exscientia
Verified email at exscientia.co.uk
Title
Cited by
Cited by
Year
The RCSB protein data bank: integrative view of protein, gene and 3D structural information
PW Rose, A Prlić, A Altunkaya, C Bi, AR Bradley, CH Christie, ...
Nucleic acids research, gkw1000, 2016
5052016
NGL viewer: web-based molecular graphics for large complexes
AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić, PW Rose
Bioinformatics 34 (21), 3755-3758, 2018
2222018
A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density
NM Pearce, T Krojer, AR Bradley, P Collins, RP Nowak, R Talon, ...
Nature communications 8 (1), 1-8, 2017
832017
Web-based molecular graphics for large complexes
AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić, PW Rose
Proceedings of the 21st international conference on Web3D technology, 185-186, 2016
822016
A poised fragment library enables rapid synthetic expansion yielding the first reported inhibitors of PHIP (2), an atypical bromodomain
OB Cox, T Krojer, P Collins, O Monteiro, R Talon, A Bradley, O Fedorov, ...
Chemical science 7 (3), 2322-2330, 2016
662016
Rapid covalent-probe discovery by electrophile-fragment screening
E Resnick, A Bradley, J Gan, A Douangamath, T Krojer, R Sethi, ...
Journal of the American Chemical Society 141 (22), 8951-8968, 2019
522019
Protein family-specific models using deep neural networks and transfer learning improve virtual screening and highlight the need for more data
F Imrie, AR Bradley, M van der Schaar, CM Deane
Journal of chemical information and modeling 58 (11), 2319-2330, 2018
342018
MMTF—An efficient file format for the transmission, visualization, and analysis of macromolecular structures
AR Bradley, AS Rose, A Pavelka, Y Valasatava, JM Duarte, A Prlić, ...
PLoS computational biology 13 (6), e1005575, 2017
302017
Deep Generative Models for 3D Linker Design
F Imrie, AR Bradley, M van der Schaar, CM Deane
Journal of chemical information and modeling 60 (4), 1983-1995, 2020
132020
BioJava 5: A community driven open-source bioinformatics library
A Lafita, S Bliven, A Prlić, D Guzenko, PW Rose, A Bradley, P Pavan, ...
PLoS computational biology 15 (2), e1006791, 2019
132019
Partial-occupancy binders identified by the Pan-Dataset Density Analysis method offer new chemical opportunities and reveal cryptic binding sites
NM Pearce, AR Bradley, T Krojer, BD Marsden, CM Deane, F Von Delft
Structural Dynamics 4 (3), 032104, 2017
112017
Towards an efficient compression of 3D coordinates of macromolecular structures
Y Valasatava, AR Bradley, AS Rose, JM Duarte, A Prlić, PW Rose
PLoS One 12 (3), e0174846, 2017
92017
RCSB Protein Data Bank (PDB)
HM Berman, J Westbrook, Z Feng, G Gilliland, TN Bhat, H Weissig, ...
Nucleic Acids Res 28, 235-242, 2000
92000
OOMMPPAA: a tool to aid directed synthesis by the combined analysis of activity and structural data
AR Bradley, ID Wall, DVS Green, CM Deane, BD Marsden
Journal of chemical information and modeling 54 (10), 2636-2646, 2014
82014
The SGC beyond structural genomics: redefining the role of 3D structures by coupling genomic stratification with fragment-based discovery
RLM van Montfort, P Workman, AR Bradley, A Echalier, M Fairhead, ...
Essays in biochemistry 61 (5), 495-503, 2017
62017
WONKA: objective novel complex analysis for ensembles of protein–ligand structures
AR Bradley, ID Wall, F von Delft, DVS Green, CM Deane, BD Marsden
Journal of computer-aided molecular design 29 (10), 963-973, 2015
42015
A multi-crystal method for extracting obscured signal from crystallographic electron density
NM Pearce, AR Bradley, P Collins, T Krojer, RP Nowak, R Talon, ...
bioRxiv, 073411, 2016
32016
Deep generative models for 3D compound design
F Imrie, AR Bradley, M Van Der Schaar, CM Deane
BioRxiv, 830497, 2019
22019
WONKA and OOMMPPAA: analysis of protein–ligand interaction data to direct structure-based drug design
CM Deane, ID Wall, DVS Green, BD Marsden, AR Bradley
Acta Crystallographica Section D: Structural Biology 73 (3), 279-285, 2017
22017
Human Pleckstrin Homology domain Interacting Protein (PHIP)
OB Cox, T Krojer, P Collins, O Monteiro, R Talon, A Bradley, O Fedorov, ...
A Target Enabling Package 10, 2016
22016
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Articles 1–20