Neurotoxins and their binding areas on voltage-gated sodium channels M Stevens, S Peigneur, J Tytgat Frontiers in pharmacology 2, 71, 2011 | 189 | 2011 |
Conotoxins targeting nicotinic acetylcholine receptors: an overview EKM Lebbe, S Peigneur, I Wijesekara, J Tytgat Marine drugs 12 (5), 2970-3004, 2014 | 107 | 2014 |
A bifunctional sea anemone peptide with Kunitz type protease and potassium channel inhibiting properties S Peigneur, B Billen, R Derua, E Waelkens, S Debaveye, L Béress, ... Biochemical pharmacology 82 (1), 81-90, 2011 | 101 | 2011 |
A natural point mutation changes both target selectivity and mechanism of action of sea anemone toxins S Peigneur, L Béress, C Möller, F Marí, WG Forssmann, J Tytgat The FASEB Journal 26 (12), 5141-5151, 2012 | 75 | 2012 |
Experimental conversion of a defensin into a neurotoxin: implications for origin of toxic function S Zhu, S Peigneur, B Gao, Y Umetsu, S Ohki, J Tytgat Molecular biology and evolution 31 (3), 546-559, 2014 | 63 | 2014 |
Molecular diversity and functional evolution of scorpion potassium channel toxins S Zhu, S Peigneur, B Gao, L Luo, D Jin, Y Zhao, J Tytgat Molecular & Cellular Proteomics 10 (2), S1-S11, 2011 | 60 | 2011 |
A novel sea anemone peptide that inhibits acid-sensing ion channels AA Rodríguez, E Salceda, AG Garateix, AJ Zaharenko, S Peigneur, ... Peptides 53, 3-12, 2014 | 58 | 2014 |
Evolutionary diversification of Mesobuthus α-scorpion toxins affecting sodium channels S Zhu, S Peigneur, B Gao, X Lu, C Cao, J Tytgat Molecular & Cellular Proteomics 11 (1), M111. 012054, 2012 | 56 | 2012 |
Crotamine pharmacology revisited: novel insights based on the inhibition of KV channels S Peigneur, DJB Orts, ARP da Silva, N Oguiura, M Boni-Mitake, ... Molecular pharmacology 82 (1), 90-96, 2012 | 52 | 2012 |
Molecular diversity of the telson and venom components from Pandinus cavimanus (Scorpionidae Latreille 1802): Transcriptome, venomics and function E Diego‐García, S Peigneur, E Clynen, T Marien, L Czech, L Schoofs, ... Proteomics 12 (2), 313-328, 2012 | 52 | 2012 |
MeuTXKβ1, a scorpion venom-derived two-domain potassium channel toxin-like peptide with cytolytic activity S Zhu, B Gao, A Aumelas, M del Carmen Rodríguez, H Lanz-Mendoza, ... Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1804 (4), 872-883, 2010 | 50 | 2010 |
Crystal structures of a cysteine-modified mutant in loop D of acetylcholine-binding protein M Brams, EA Gay, JC Sáez, A Guskov, R van Elk, RC van der Schors, ... Journal of Biological Chemistry 286 (6), 4420-4428, 2011 | 47 | 2011 |
A potent potassium channel blocker from Mesobuthus eupeus scorpion venom B Gao, S Peigneur, J Tytgat, S Zhu Biochimie 92 (12), 1847-1853, 2010 | 40 | 2010 |
Variability of potassium channel blockers in Mesobuthus eupeus scorpion venom with focus on Kv1. 1: An integrated transcriptomic and proteomic study AI Kuzmenkov, AA Vassilevski, KS Kudryashova, OV Nekrasova, ... Journal of biological chemistry 290 (19), 12195-12209, 2015 | 39 | 2015 |
Venom components from Citharischius crawshayi spider (Family Theraphosidae): exploring transcriptome, venomics, and function E Diego-García, S Peigneur, E Waelkens, S Debaveye, J Tytgat Cellular and molecular life sciences 67 (16), 2799-2813, 2010 | 38 | 2010 |
Investigation of the relationship between the structure and function of Ts2, a neurotoxin from Tityus serrulatus venom CT Cologna, S Peigneur, JK Rustiguel, MC Nonato, J Tytgat, EC Arantes The FEBS journal 279 (8), 1495-1504, 2012 | 37 | 2012 |
Identification, structural and pharmacological characterization of τ-CnVA, a conopeptide that selectively interacts with somatostatin sst3 receptor C Petrel, HG Hocking, M Reynaud, G Upert, P Favreau, D Biass, ... Biochemical pharmacology 85 (11), 1663-1671, 2013 | 36 | 2013 |
A gamut of undiscovered electrophysiological effects produced by Tityus serrulatus toxin 1 on NaV-type isoforms S Peigneur, CT Cologna, CM Cremonez, BG Mille, MB Pucca, E Cuypers, ... Neuropharmacology 95, 269-277, 2015 | 35 | 2015 |
Multiple actions of φ-LITX-Lw1a on ryanodine receptors reveal a functional link between scorpion DDH and ICK toxins JJ Smith, I Vetter, RJ Lewis, S Peigneur, J Tytgat, A Lam, EM Gallant, ... Proceedings of the National Academy of Sciences 110 (22), 8906-8911, 2013 | 35 | 2013 |
Kunitz-type peptide HCRG21 from the sea anemone Heteractis crispa is a full antagonist of the TRPV1 receptor M Monastyrnaya, S Peigneur, E Zelepuga, O Sintsova, I Gladkikh, ... Marine drugs 14 (12), 229, 2016 | 34 | 2016 |