Genetic studies of body mass index yield new insights for obesity biology AE Locke, B Kahali, SI Berndt, AE Justice, TH Pers, FR Day, C Powell, ... Nature 518 (7538), 197-206, 2015 | 4663 | 2015 |
New genetic loci link adipose and insulin biology to body fat distribution D Shungin, TW Winkler, DC Croteau-Chonka, T Ferreira, AE Locke, ... Nature 518 (7538), 187-196, 2015 | 1609 | 2015 |
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution IM Heid, AU Jackson, JC Randall, TW Winkler, L Qi, V Steinthorsdottir, ... Nature genetics 42 (11), 949-960, 2010 | 1100 | 2010 |
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture SI Berndt, S Gustafsson, R Mägi, A Ganna, E Wheeler, MF Feitosa, ... Nature genetics 45 (5), 501-512, 2013 | 746 | 2013 |
A comparative phenotypic and genomic analysis of C57BL/6J and C57BL/6N mouse strains MM Simon, S Greenaway, JK White, H Fuchs, V Gailus-Durner, S Wells, ... Genome biology 14 (7), 1-22, 2013 | 516 | 2013 |
Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits JC Randall, TW Winkler, Z Kutalik, SI Berndt, AU Jackson, KL Monda, ... PLoS genetics 9 (6), e1003500, 2013 | 470 | 2013 |
Alternative splicing events are a late feature of pathology in a mouse model of spinal muscular atrophy D Bäumer, S Lee, G Nicholson, JL Davies, NJ Parkinson, LM Murray, ... PLoS genetics 5 (12), e1000773, 2009 | 283 | 2009 |
Assessing population differentiation and isolation from single‐nucleotide polymorphism data G Nicholson, AV Smith, F Jónsson, Ó Gústafsson, K Stefánsson, ... Journal of the Royal Statistical Society: Series B (Statistical Methodology …, 2002 | 278 | 2002 |
Genetic markers of toxicity from capecitabine and other fluorouracil-based regimens: investigation in the QUASAR2 study, systematic review, and meta-analysis D Rosmarin, C Palles, D Church, E Domingo, A Jones, E Johnstone, ... Journal of Clinical Oncology 32 (10), 1031, 2014 | 262 | 2014 |
Reproducibility and replicability of rodent phenotyping in preclinical studies N Kafkafi, J Agassi, EJ Chesler, JC Crabbe, WE Crusio, D Eilam, R Gerlai, ... Neuroscience & Biobehavioral Reviews 87, 218-232, 2018 | 190 | 2018 |
Distinct developmental profile of lower-body adipose tissue defines resistance against obesity-associated metabolic complications KE Pinnick, G Nicholson, KN Manolopoulos, SE McQuaid, P Valet, ... Diabetes 63 (11), 3785-3797, 2014 | 186 | 2014 |
Adult Onset Global Loss of the Fto Gene Alters Body Composition and Metabolism in the Mouse F McMurray, CD Church, R Larder, G Nicholson, S Wells, L Teboul, ... PLoS genetics 9 (1), e1003166, 2013 | 170 | 2013 |
Human metabolic profiles are stably controlled by genetic and environmental variation G Nicholson, M Rantalainen, AD Maher, JV Li, D Malmodin, KR Ahmadi, ... Molecular systems biology 7 (1), 525, 2011 | 170 | 2011 |
Reproducibility of molecular phenotypes after long-term differentiation to human iPSC-derived neurons: a multi-site omics study V Volpato, J Smith, C Sandor, JS Ried, A Baud, A Handel, SE Newey, ... Stem cell reports 11 (4), 897-911, 2018 | 152 | 2018 |
Analysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinics M Hrabě de Angelis, G Nicholson, M Selloum, JK White, H Morgan, ... Nature genetics 47 (9), 969-978, 2015 | 144 | 2015 |
A genome-wide metabolic QTL analysis in Europeans implicates two loci shaped by recent positive selection G Nicholson, M Rantalainen, JV Li, AD Maher, D Malmodin, KR Ahmadi, ... PLoS genetics 7 (9), e1002270, 2011 | 137 | 2011 |
A reassessment of genetic diversity in Icelanders: strong evidence from multiple loci for relative homogeneity caused by genetic drift A Helgason, G Nicholson, K Stefansson, P Donnelly Annals of human genetics 67 (4), 281-297, 2003 | 132 | 2003 |
Genome-to-genome analysis highlights the effect of the human innate and adaptive immune systems on the hepatitis C virus MA Ansari, V Pedergnana, C LC Ip, A Magri, A Von Delft, D Bonsall, ... Nature genetics 49 (5), 666-673, 2017 | 125 | 2017 |
Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability V Lagou, R Mägi, JJ Hottenga, H Grallert, JRB Perry, N Bouatia-Naji, ... Nature communications 12 (1), 24, 2021 | 118 | 2021 |
The presence of methylation quantitative trait loci indicates a direct genetic influence on the level of DNA methylation in adipose tissue AW Drong, G Nicholson, ÅK Hedman, E Meduri, E Grundberg, KS Small, ... PloS one 8 (2), e55923, 2013 | 98 | 2013 |