Pedro A Valiente
Pedro A Valiente
Donnelly Center for Cellular and Biomolecular Research, Faculty of Medicine, University of Toronto
Verified email at utoronto.ca
Title
Cited by
Cited by
Year
Differences in activity of actinoporins are related with the hydrophobicity of their N-terminus
U Ros, W Rodríguez-Vera, L Pedrera, PA Valiente, S Cabezas, ME Lanio, ...
Biochimie 116, 70-78, 2015
252015
Predicting functional residues in Plasmodium falciparum plasmepsins by combining sequence and structural analysis with molecular dynamics simulations
PA Valiente, PR Batista, A Pupo, T Pons, A Valencia, PG Pascutti
Proteins: Structure, Function, and Bioinformatics 73 (2), 440-457, 2008
222008
Computational proteomics pitfalls and challenges: HavanaBioinfo 2012 workshop report
Y Perez-Riverol, H Hermjakob, O Kohlbacher, L Martens, D Creasy, J Cox, ...
Journal of proteomics 87, 134-138, 2013
212013
The membranotropic activity of N-terminal peptides from the pore-forming proteins sticholysin I and II is modulated by hydrophobic and electrostatic interactions as well as …
U Ros, L Pedrera, D Díaz, JC De Karam, TP Sudbrack, PA Valiente, ...
Journal of biosciences 36 (5), 781-791, 2011
212011
Unraveling the binding mechanism of polyoxyethylene sorbitan esters with bovine serum albumin: A novel theoretical model based on molecular dynamic simulations
KH Delgado-Magnero, PA Valiente, M Ruiz-Peña, A Pérez-Gramatges, ...
Colloids and Surfaces B: Biointerfaces 116, 720-726, 2014
192014
Computational Perspectives into Plasmepsins Structure—Function Relationship: Implications to Inhibitors Design
A Gil L, PA Valiente, PG Pascutti, T Pons
Journal of tropical medicine 2011, 2011
192011
Disrupting a key hydrophobic pair in the oligomerization interface of the actinoporins impairs their pore‐forming activity
H Mesa‐Galloso, KH Delgado‐Magnero, S Cabezas, A López‐Castilla, ...
Protein Science 26 (3), 550-565, 2017
182017
Improving the LIE method for binding free energy calculations of protein–ligand complexes
WE Miranda, SY Noskov, PA Valiente
Journal of chemical information and modeling 55 (9), 1867-1877, 2015
182015
Structural insights into serine protease inhibition by a marine invertebrate BPTI Kunitz-type inhibitor
R García-Fernández, T Pons, M Perbandt, PA Valiente, A Talavera, ...
Journal of structural biology 180 (2), 271-279, 2012
182012
New parameterization approaches of the LIE method to improve free energy calculations of PlmII‐Inhibitors complexes
PA Valiente, A Gil L, PR Batista, ER Caffarena, T Pons, PG Pascutti
Journal of computational chemistry 31 (15), 2723-2734, 2010
182010
Identification of inhibitors of CD36-amyloid beta binding as potential agents for Alzheimer’s disease
D Doens, PA Valiente, AM Mfuh, A XT Vo, A Tristan, L Carreño, M Quijada, ...
ACS chemical neuroscience 8 (6), 1232-1241, 2017
152017
Discovery of potent and selective inhibitors of the Escherichia coli M1-aminopeptidase via multicomponent solid-phase synthesis of tetrazole-peptidomimetics
Y Méndez, G De Armas, I Pérez, T Rojas, ME Valdés-Tresanco, ...
European Journal of Medicinal Chemistry 163, 481-499, 2019
102019
Predicting binding modes of reversible peptide‐based inhibitors of falcipain‐2 consistent with structure–activity relationships
JE Hernandez Gonzalez, L Hernández Alvarez, PG Pascutti, PA Valiente
Proteins: Structure, Function, and Bioinformatics 85 (9), 1666-1683, 2017
102017
Differential binding and activity of the pore-forming toxin sticholysin II in model membranes containing diverse ceramide-derived lipids
C Soto, A del Valle, PA Valiente, U Ros, ME Lanio, AM Hernández, ...
Biochimie 138, 20-31, 2017
102017
Biophysical and biochemical strategies to understand membrane binding and pore formation by sticholysins, pore-forming proteins from a sea anemone
C Alvarez, U Ros, A Valle, L Pedrera, C Soto, YP Hervis, S Cabezas, ...
Biophysical reviews 9 (5), 529-544, 2017
92017
Effect of zinc and calcium ions on the rat kidney membrane-bound form of dipeptidyl peptidase IV
H Gómez, M Chappé, PA Valiente, T Pons, MLA Chávez, JL Charli, ...
Journal of biosciences 38 (3), 461-469, 2013
72013
Discovery of novel non-competitive inhibitors of mammalian neutral M1 aminopeptidase (APN)
I Pascual, PA Valiente, G García, ME Valdés-Tresanco, Y Arrebola, L Díaz, ...
Biochimie 142, 216-225, 2017
62017
Identification of (4-(9H-fluoren-9-yl) piperazin-1-yl) methanone derivatives as falcipain 2 inhibitors active against Plasmodium falciparum cultures
JE Hernández-González, E Salas-Sarduy, LFH Ramírez, MJ Pascual, ...
Biochimica et Biophysica Acta (BBA)-General Subjects 1862 (12), 2911-2923, 2018
52018
Polar desolvation and position 226 of pancreatic and neutrophil elastases are crucial to their affinity for the Kunitz-type inhibitors ShPI-1 and ShPI-1/K13L
JEH González, R García-Fernández, PA Valiente
PloS one 10 (9), e0137787, 2015
52015
ROLE OF LACASSE ISOZYMES IN DIVERSITY OF LACCASE GENES FR
AM Manzano, G Torres, PA VALIENTE, MI SÁNCHEZ
Journal of Applied Sciences in Environmental Sanitation 8 (4), 237-242, 2013
42013
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