Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas C Palles, JB Cazier, KM Howarth, E Domingo, AM Jones, P Broderick, ... Nature genetics 45 (2), 136-144, 2013 | 1110 | 2013 |
DNA polymerase ɛ and δ exonuclease domain mutations in endometrial cancer DN Church, SEW Briggs, C Palles, E Domingo, SJ Kearsey, JM Grimes, ... Human molecular genetics 22 (14), 2820-2828, 2013 | 405 | 2013 |
The 5′ end of yeast 5.8 S rRNA is generated by exonucleases from an upstream cleavage site. Y Henry, H Wood, JP Morrissey, E Petfalski, S Kearsey, D Tollervey The EMBO journal 13 (10), 2452-2463, 1994 | 388 | 1994 |
MCM proteins: evolution, properties, and role in DNA replication SE Kearsey, K Labib Biochimica et Biophysica Acta (BBA)-Gene Structure and Expression 1398 (2 …, 1998 | 377 | 1998 |
A panoply of errors: polymerase proofreading domain mutations in cancer E Rayner, IC Van Gool, C Palles, SE Kearsey, T Bosse, I Tomlinson, ... Nature Reviews Cancer 16 (2), 71-81, 2016 | 355 | 2016 |
Characterization of fission yeast cohesin: essential anaphase proteolysis of Rad21 phosphorylated in the S phase T Tomonaga, K Nagao, Y Kawasaki, K Furuya, A Murakami, J Morishita, ... Genes & Development 14 (21), 2757-2770, 2000 | 341 | 2000 |
BM28, a human member of the MCM2-3-5 family, is displaced from chromatin during DNA replication. IT Todorov, A Attaran, SE Kearsey The Journal of cell biology 129 (6), 1433-1445, 1995 | 296 | 1995 |
Nucleoplasmin cDNA sequence reveals polyglutamic acid tracts and a cluster of sequences homologous to putative nuclear localization signals. C Dingwall, SM Dilworth, SJ Black, SE Kearsey, LS Cox, RA Laskey The EMBO journal 6 (1), 69-74, 1987 | 290 | 1987 |
G1-phase and B-type cyclins exclude the DNA-replication factor Mcm4 from the nucleus K Labib, JFX Diffley, SE Kearsey Nature cell biology 1 (7), 415-422, 1999 | 281 | 1999 |
Structural requirements for the function of a yeast chromosomal replicator S Kearsey Cell 37 (1), 299-307, 1984 | 241 | 1984 |
Lack of specific sequence requirement for DNA replication in Xenopus eggs compared with high sequence specificity in yeast M Méchali, S Kearsey Cell 38 (1), 55-64, 1984 | 231 | 1984 |
MCM2–7 proteins are essential components of prereplicative complexes that accumulate cooperatively in the nucleus during G1-phase and are required to establish, but not … K Labib, SE Kearsey, JFX Diffley Molecular biology of the cell 12 (11), 3658-3667, 2001 | 190 | 2001 |
Altered ribosomal RNA genes in mitochondria from mammalian cells with chloramphenicol resistance SE Kearsey, IW Craig Nature 290 (5807), 607-608, 1981 | 172 | 1981 |
A critical balance: dNTPs and the maintenance of genome stability CC Pai, SE Kearsey Genes 8 (2), 57, 2017 | 171 | 2017 |
The role of MCM proteins in the cell cycle control of genome duplication SE Kearsey, D Maiorano, EC Holmes, IT Todorov Bioessays 18 (3), 183-190, 1996 | 171 | 1996 |
Chromotin binding, nuclear localization and phosphorylation of Xenopus cdc21 are cell‐cycle dependent and associated with the control of initiation of DNA replication. M Coue, SE Kearsey, M Mechali The EMBO journal 15 (5), 1085-1097, 1996 | 158 | 1996 |
Fission yeast cdc21+ belongs to a family of proteins involved in an early step of chromosome replication A Coxon, K Maundrell, SE Kearsey Nucleic acids research 20 (21), 5571-5577, 1992 | 152 | 1992 |
A human nuclear protein with sequence homology to a family of early S phase proteins is required for entry into S phase and for cell division IT Todorov, R Pepperkok, RN Philipova, SE Kearsey, W Ansorge, ... Journal of cell science 107 (1), 253-265, 1994 | 147 | 1994 |
Fission yeast Cdc23/Mcm10 functions after pre-replicative complex formation to promote Cdc45 chromatin binding J Gregan, K Lindner, L Brimage, R Franklin, M Namdar, EA Hart, SJ Aves, ... Molecular biology of the cell 14 (9), 3876-3887, 2003 | 145 | 2003 |
Enigmatic variations: divergent modes of regulating eukaryotic DNA replication SE Kearsey, S Cotterill Molecular cell 12 (5), 1067-1075, 2003 | 120 | 2003 |