Agonists of proteinase-activated receptor 2 induce inflammation by a neurogenic mechanism M Steinhoff, N Vergnolle, SH Young, M Tognetto, S Amadesi, HS Ennes, ... Nature medicine 6 (2), 151-158, 2000 | 1069 | 2000 |
NSAID-induced gastric damage in rats: requirement for inhibition of both cyclooxygenase 1 and 2 JL Wallace, W McKnight, BK Reuter, N Vergnolle Gastroenterology 119 (3), 706-714, 2000 | 899 | 2000 |
Role for protease activity in visceral pain in irritable bowel syndrome N Cenac, CN Andrews, M Holzhausen, K Chapman, G Cottrell, ... The Journal of clinical investigation 117 (3), 636-647, 2007 | 669 | 2007 |
Proteinase-activated receptors: transducers of proteinase-mediated signaling in inflammation and immune response M Steinhoff, J Buddenkotte, V Shpacovitch, A Rattenholl, C Moormann, ... Endocrine reviews 26 (1), 1-43, 2005 | 608 | 2005 |
Proteinase-activated receptor-2 and hyperalgesia: a novel pain pathway N Vergnolle, NW Bunnett, KA Sharkey, V Brussee, SJ Compton, EF Grady, ... Nature medicine 7 (7), 821-826, 2001 | 533 | 2001 |
Protease-activated receptor 2 sensitizes the capsaicin receptor transient receptor potential vanilloid receptor 1 to induce hyperalgesia S Amadesi, J Nie, N Vergnolle, GS Cottrell, EF Grady, M Trevisani, ... Journal of Neuroscience 24 (18), 4300-4312, 2004 | 459 | 2004 |
Induction of intestinal inflammation in mouse by activation of proteinase-activated receptor-2 N Cenac, AM Coelho, C Nguyen, S Compton, P Andrade-Gordon, ... The American journal of pathology 161 (5), 1903-1915, 2002 | 430 | 2002 |
Protease-activated receptors in inflammation, neuronal signaling and pain N Vergnolle, JL Wallace, NW Bunnett, MD Hollenberg Trends in pharmacological sciences 22 (3), 146-152, 2001 | 425 | 2001 |
Protease‐activated receptor 2 sensitizes the transient receptor potential vanilloid 4 ion channel to cause mechanical hyperalgesia in mice AD Grant, GS Cottrell, S Amadesi, M Trevisani, P Nicoletti, S Materazzi, ... The Journal of physiology 578 (3), 715-733, 2007 | 413 | 2007 |
The intestinal microenvironment and functional gastrointestinal disorders G Barbara, C Feinle-Bisset, UC Ghoshal, J Santos, SJ Vanner, ... Gastroenterology 150 (6), 1305-1318. e8, 2016 | 312 | 2016 |
Protease‐activated receptor 2 sensitizes TRPV1 by protein kinase Cɛ‐and A‐dependent mechanisms in rats and mice S Amadesi, GS Cottrell, L Divino, K Chapman, EF Grady, F Bautista, ... The Journal of physiology 575 (2), 555-571, 2006 | 300 | 2006 |
Proteinase-activated receptor-2-activating peptides induce leukocyte rolling, adhesion, and extravasation in vivo N Vergnolle The Journal of Immunology 163 (9), 5064-5069, 1999 | 258 | 1999 |
Proteinases and proteinase-activated receptor 2: a possible role to promote visceral hyperalgesia in rats AM Coelho, N Vergnolle, B Guiard, J Fioramonti, L Bueno Gastroenterology 122 (4), 1035-1047, 2002 | 253 | 2002 |
Characterization of the inflammatory response to proteinase‐activated receptor‐2 (PAR2)‐activating peptides in the rat paw N Vergnolle, MD Hollenberg, KA Sharkey, JL Wallace British journal of pharmacology 127 (5), 1083-1090, 1999 | 249 | 1999 |
Proteinase-activated receptor 2 is an anti-inflammatory signal for colonic lamina propria lymphocytes in a mouse model of colitis S Fiorucci, A Mencarelli, B Palazzetti, E Distrutti, N Vergnolle, ... Proceedings of the National Academy of Sciences 98 (24), 13936-13941, 2001 | 241 | 2001 |
Food-grade bacteria expressing elafin protect against inflammation and restore colon homeostasis JP Motta, LG Bermúdez-Humarán, C Deraison, L Martin, C Rolland, ... Science translational medicine 4 (158), 158ra144-158ra144, 2012 | 231 | 2012 |
A major role for proteolytic activity and proteinase-activated receptor-2 in the pathogenesis of infectious colitis KK Hansen, PM Sherman, L Cellars, P Andrade-Gordon, Z Pan, A Baruch, ... Proceedings of the National Academy of Sciences 102 (23), 8363-8368, 2005 | 203 | 2005 |
Clinical relevance of proteinase activated receptors (pars) in the gut N Vergnolle Gut 54 (6), 867-874, 2005 | 200 | 2005 |
Proteinase-activated receptor 1 activation induces epithelial apoptosis and increases intestinal permeability AC Chin, N Vergnolle, WK MacNaughton, JL Wallace, MD Hollenberg, ... Proceedings of the national academy of sciences 100 (19), 11104-11109, 2003 | 190 | 2003 |
Proteinase-activated receptor 2 (PAR2)-activating peptides: Identification of a receptor distinct from PAR2 that regulates intestinal transport N Vergnolle, WK Macnaughton, B Al-Ani, M Saifeddine, JL Wallace, ... Proceedings of the National Academy of Sciences 95 (13), 7766-7771, 1998 | 189 | 1998 |