Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters M Feuerer, L Herrero, D Cipolletta, A Naaz, J Wong, A Nayer, J Lee, ... Nature medicine 15 (8), 930-939, 2009 | 2335 | 2009 |
From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus K Musunuru, A Strong, M Frank-Kamenetsky, NE Lee, T Ahfeldt, KV Sachs, ... Nature 466 (7307), 714-719, 2010 | 1236 | 2010 |
Therapeutic siRNA silencing in inflammatory monocytes in mice F Leuschner, P Dutta, R Gorbatov, TI Novobrantseva, JS Donahoe, ... Nature biotechnology 29 (11), 1005-1010, 2011 | 857 | 2011 |
Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates M Frank-Kamenetsky, A Grefhorst, NN Anderson, TS Racie, B Bramlage, ... Proceedings of the National Academy of Sciences 105 (33), 11915-11920, 2008 | 801 | 2008 |
Adaptation of TCR repertoires to self-peptides in regulatory and nonregulatory CD4+ T cells J Wong, R Obst, M Correia-Neves, G Losyev, D Mathis, C Benoist The Journal of Immunology 178 (11), 7032-7041, 2007 | 242 | 2007 |
Mismatch repair co-opted by hypermutation M Cascalho, J Wong, C Steinberg, M Wabl Science 279 (5354), 1207-1210, 1998 | 199 | 1998 |
Systemic RNAi-mediated gene silencing in nonhuman primate and rodent myeloid cells TI Novobrantseva, A Borodovsky, J Wong, B Klebanov, M Zafari, K Yucius, ... Molecular Therapy-Nucleic Acids 1, 2012 | 138 | 2012 |
Improving dendritic cell vaccine immunogenicity by silencing PD-1 ligands using siRNA-lipid nanoparticles combined with antigen mRNA electroporation W Hobo, TI Novobrantseva, H Fredrix, J Wong, S Milstein, ... Cancer Immunology, Immunotherapy 62, 285-297, 2013 | 129 | 2013 |
TCR-based lineage tracing: no evidence for conversion of conventional into regulatory T cells in response to a natural self-antigen in pancreatic islets J Wong, D Mathis, C Benoist The Journal of experimental medicine 204 (9), 2039-2045, 2007 | 113 | 2007 |
VH gene replacement in hyperselected B cells of the quasimonoclonal mouse. M Cascalho, J Wong, M Wabl Journal of immunology (Baltimore, Md.: 1950) 159 (12), 5795-5801, 1997 | 91 | 1997 |
Anti-CD3 therapy permits regulatory T cells to surmount T cell receptor–specified peripheral niche constraints J Nishio, M Feuerer, J Wong, D Mathis, C Benoist Journal of Experimental Medicine 207 (9), 1879-1889, 2010 | 76 | 2010 |
Treatment of erythropoietin deficiency in mice with systemically administered siRNA W Querbes, RL Bogorad, J Moslehi, J Wong, AY Chan, E Bulgakova, ... Blood, The Journal of the American Society of Hematology 120 (9), 1916-1922, 2012 | 57 | 2012 |
HDAC3 inhibition ameliorates spinal cord injury by immunomodulation T Kuboyama, S Wahane, Y Huang, X Zhou, JK Wong, A Koemeter-Cox, ... Scientific reports 7 (1), 8641, 2017 | 51 | 2017 |
Indocyanine green hyperfluorescence associated with serous retinal pigment epithelial detachment in age-related macular degeneration CR Baumal, E Reichel, JS Duker, J Wong, CA Puliafito Ophthalmology 104 (5), 761-769, 1997 | 42 | 1997 |
Fat Treg cells: a liaison between the immune and metabolic systems M Feuerer, L Herrero, D Cipolletta, A Naaz, J Wong, A Nayer, J Lee, ... Nature medicine 15 (8), 930, 2009 | 39 | 2009 |
B cell immunopoiesis: visualizing the impact of CD40 engagement on the course of T cell‐independent immune responses in an Ig transgenic system LD Erickson, LA Vogel, M Cascalho, J Wong, M Wabl, BG Durell, ... European journal of immunology 30 (11), 3121-3131, 2000 | 33 | 2000 |
Rapid identification of a novel small molecule phosphodiesterase 10A (PDE10A) tracer E Hu, J Ma, C Biorn, D Lester-Zeiner, R Cho, S Rumfelt, RK Kunz, T Nixey, ... Journal of medicinal chemistry 55 (10), 4776-4787, 2012 | 31 | 2012 |
Synthesis and SAR study of potent and selective PI3Kδ inhibitors M Bui, X Hao, Y Shin, M Cardozo, X He, K Henne, J Suchomel, ... Bioorganic & medicinal chemistry letters 25 (5), 1104-1109, 2015 | 24 | 2015 |
Ig heavy chain promotes mature B cell survival in the absence of light chain P Geraldes, M Rebrovich, K Herrmann, J Wong, HM Jäck, M Wabl, ... The Journal of Immunology 179 (3), 1659-1668, 2007 | 24 | 2007 |
A B220–, CD19–population of B cells in the peripheral blood of quasimonoclonal mice M Cascalho, J Wong, J Brown, HM Jäck, C Steinberg, M Wabl International immunology 12 (1), 29-35, 2000 | 24 | 2000 |