| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13161* | 2021 |
| Extensive involvement of autophagy in Alzheimer disease: an immuno-electron microscopy study RA Nixon, J Wegiel, A Kumar, WH Yu, C Peterhoff, A Cataldo, AM Cuervo Journal of Neuropathology & Experimental Neurology 64 (2), 113-122, 2005 | 1712 | 2005 |
| Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and βAPP processing G Yu, M Nishimura, S Arawaka, D Levitan, L Zhang, A Tandon, YQ Song, ... Nature 407 (6800), 48-54, 2000 | 1287 | 2000 |
| Lysosomal proteolysis and autophagy require presenilin 1 and are disrupted by Alzheimer-related PS1 mutations JH Lee, WH Yu, A Kumar, S Lee, PS Mohan, CM Peterhoff, DM Wolfe, ... Cell 141 (7), 1146-1158, 2010 | 1244 | 2010 |
| Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's disease B Boland, A Kumar, S Lee, FM Platt, J Wegiel, WH Yu, RA Nixon Journal of Neuroscience 28 (27), 6926-6937, 2008 | 1227 | 2008 |
| Macroautophagy—a novel β-amyloid peptide-generating pathway activated in Alzheimer's disease WH Yu, AM Cuervo, A Kumar, CM Peterhoff, SD Schmidt, JH Lee, ... The Journal of cell biology 171 (1), 87-98, 2005 | 1161 | 2005 |
| Understanding the impact of sex and gender in Alzheimer's disease: a call to action RA Nebel, NT Aggarwal, LL Barnes, A Gallagher, JM Goldstein, ... Alzheimer's & Dementia 14 (9), 1171-1183, 2018 | 608 | 2018 |
| Promoting the clearance of neurotoxic proteins in neurodegenerative disorders of ageing B Boland, WH Yu, O Corti, B Mollereau, A Henriques, E Bezard, ... Nature reviews Drug discovery 17 (9), 660-688, 2018 | 435 | 2018 |
| Tau-driven 26S proteasome impairment and cognitive dysfunction can be prevented early in disease by activating cAMP-PKA signaling N Myeku, CL Clelland, S Emrani, NV Kukushkin, WH Yu, AL Goldberg, ... Nature medicine 22 (1), 46-53, 2016 | 409 | 2016 |
| Presenilins are enriched in endoplasmic reticulum membranes associated with mitochondria E Area-Gomez, AJC de Groof, I Boldogh, TD Bird, GE Gibson, CM Koehler, ... The American journal of pathology 175 (5), 1810-1816, 2009 | 399 | 2009 |
| Autophagic vacuoles are enriched in amyloid precursor protein-secretase activities: implications for β-amyloid peptide over-production and localization in Alzheimer’s disease WH Yu, A Kumar, C Peterhoff, LS Kulnane, Y Uchiyama, BT Lamb, ... The international journal of biochemistry & cell biology 36 (12), 2531-2540, 2004 | 375 | 2004 |
| Methylthioninium chloride (methylene blue) induces autophagy and attenuates tauopathy in vitro and in vivo EE Congdon, JW Wu, N Myeku, YH Figueroa, M Herman, PS Marinec, ... Autophagy 8 (4), 609-622, 2012 | 322 | 2012 |
| Insulin dysfunction induces in vivo tau hyperphosphorylation through distinct mechanisms E Planel, Y Tatebayashi, T Miyasaka, L Liu, L Wang, M Herman, WH Yu, ... Journal of Neuroscience 27 (50), 13635-13648, 2007 | 300 | 2007 |
| Augmenting CNS glucocerebrosidase activity as a therapeutic strategy for parkinsonism and other Gaucher-related synucleinopathies SP Sardi, J Clarke, C Viel, M Chan, TJ Tamsett, CM Treleaven, J Bu, ... Proceedings of the National Academy of Sciences 110 (9), 3537-3542, 2013 | 285 | 2013 |
| Extracellular tau oligomers produce an immediate impairment of LTP and memory M Fá, D Puzzo, R Piacentini, A Staniszewski, H Zhang, MA Baltrons, ... Scientific reports 6 (1), 19393, 2016 | 265 | 2016 |
| Contrasting pathology of the stress granule proteins TIA-1 and G3BP in tauopathies T Vanderweyde, H Yu, M Varnum, L Liu-Yesucevitz, A Citro, T Ikezu, ... Journal of Neuroscience 32 (24), 8270-8283, 2012 | 242 | 2012 |
| Transcriptional regulation of β-secretase by p25/cdk5 leads to enhanced amyloidogenic processing Y Wen, WH Yu, B Maloney, J Bailey, J Ma, I Marié, T Maurin, L Wang, ... Neuron 57 (5), 680-690, 2008 | 225 | 2008 |
| Metallothionein III is reduced in Alzheimer’s disease WH Yu, WJ Lukiw, C Bergeron, HB Niznik, PE Fraser Brain research 894 (1), 37-45, 2001 | 216 | 2001 |
| Mature Glycosylation and Trafficking of Nicastrin Modulate Its Binding to Presenilins* 210 DS Yang, A Tandon, F Chen, G Yu, H Yu, S Arawaka, H Hasegawa, ... Journal of Biological Chemistry 277 (31), 28135-28142, 2002 | 209 | 2002 |
| Metabolic activity determines efficacy of macroautophagic clearance of pathological oligomeric α-synuclein WH Yu, B Dorado, HY Figueroa, L Wang, E Planel, MR Cookson, ... The American journal of pathology 175 (2), 736-747, 2009 | 186 | 2009 |
Stephen D. SchmidtVaccine ScientistVerified email at nih.gov
