Integrative analysis of 111 reference human epigenomes A Kundaje, W Meuleman, J Ernst, M Bilenky, A Yen, A Heravi-Moussavi, ... Nature 518 (7539), 317-330, 2015 | 6335 | 2015 |
An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues MR Corces, AE Trevino, EG Hamilton, PG Greenside, ... Nature methods 14 (10), 959-962, 2017 | 2044 | 2017 |
Pan-cancer analysis of whole genomes. S Hirano, L Yang, M Juul, CA Purdie, BP O'Neill, R Kabbe, ... Nature 578 (DKFZ-2020-01051), 82-93, 2020 | 1927* | 2020 |
Super-resolution chromatin tracing reveals domains and cooperative interactions in single cells B Bintu, LJ Mateo, JH Su, NA Sinnott-Armstrong, M Parker, S Kinrot, ... Science 362 (6413), eaau1783, 2018 | 872 | 2018 |
Opportunities and challenges for transcriptome-wide association studies M Wainberg, N Sinnott-Armstrong, N Mancuso, AN Barbeira, DA Knowles, ... Nature genetics 51 (4), 592-599, 2019 | 782 | 2019 |
Analyses of non-coding somatic drivers in 2,658 cancer whole genomes E Rheinbay, MM Nielsen, F Abascal, JA Wala, O Shapira, G Tiao, ... Nature 578 (7793), 102-111, 2020 | 609 | 2020 |
Genetics of 38 blood and urine biomarkers in the UK Biobank N Sinnott-Armstrong, Y Tanigawa, D Amar, NJ Mars, M Aguirre, ... bioRxiv, 2019 | 599 | 2019 |
Discovery of common and rare genetic risk variants for colorectal cancer JR Huyghe, SA Bien, TA Harrison, HM Kang, S Chen, SL Schmit, ... Nature genetics 51 (1), 76-87, 2019 | 491 | 2019 |
Reduced signal for polygenic adaptation of height in UK Biobank JJ Berg, A Harpak, N Sinnott-Armstrong, AM Joergensen, H Mostafavi, ... eLife 8, e39725, 2019 | 372 | 2019 |
SARS-CoV-2 RNA in wastewater settled solids is associated with COVID-19 cases in a large urban sewershed KE Graham, SK Loeb, MK Wolfe, D Catoe, N Sinnott-Armstrong, S Kim, ... Environmental science & technology 55 (1), 488-498, 2020 | 349 | 2020 |
GAMETES: a fast, direct algorithm for generating pure, strict, epistatic models with random architectures RJ Urbanowicz, J Kiralis, NA Sinnott-Armstrong, T Heberling, JM Fisher, ... BioData mining 5 (1), 1-14, 2012 | 248 | 2012 |
Chromatin accessibility dynamics in a model of human forebrain development AE Trevino, N Sinnott-Armstrong, J Andersen, SJ Yoon, N Huber, ... Science 367 (6476), eaay1645, 2020 | 213 | 2020 |
Large-scale genome-wide association study of coronary artery disease in genetically diverse populations C Tcheandjieu, X Zhu, AT Hilliard, SL Clarke, V Napolioni, S Ma, KM Lee, ... Nature Medicine, 1-13, 2022 | 191 | 2022 |
Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170 AM Dunning, K Michailidou, KB Kuchenbaecker, D Thompson, JD French, ... Nature genetics 48 (4), 374-386, 2016 | 166 | 2016 |
Landscape of cohesin-mediated chromatin loops in the human genome F Grubert, R Srivas, DV Spacek, M Kasowski, M Ruiz-Velasco, ... Nature 583 (7818), 737-743, 2020 | 161 | 2020 |
High-resolution genome-wide functional dissection of transcriptional regulatory regions and nucleotides in human X Wang, L He, SM Goggin, A Saadat, L Wang, N Sinnott-Armstrong, ... Nature communications 9 (1), 1-15, 2018 | 150 | 2018 |
Characterizing genetic interactions in human disease association studies using statistical epistasis networks T Hu, NA Sinnott-Armstrong, JW Kiralis, AS Andrew, MR Karagas, ... BMC bioinformatics 12 (1), 1-13, 2011 | 145 | 2011 |
A genome-wide atlas of co-essential modules assigns function to uncharacterized genes M Wainberg, RA Kamber, A Balsubramani, RM Meyers, ... Nature Genetics 53 (5), 638-649, 2021 | 142 | 2021 |
GWAS of three molecular traits highlights core genes and pathways alongside a highly polygenic background N Sinnott-Armstrong, S Naqvi, M Rivas, JK Pritchard Elife 10, e58615, 2021 | 136 | 2021 |
p53 is a central regulator driving neurodegeneration caused by C9orf72 poly (PR) M Maor-Nof, Z Shipony, R Lopez-Gonzalez, L Nakayama, YJ Zhang, ... Cell 184 (3), 689-708. e20, 2021 | 131 | 2021 |