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Matti Lepistö
Matti Lepistö
RIA iMed AstraZeneca
Verified email at astrazeneca.com
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Cited by
Year
Highly enantioselective and substrate-selective polymers obtained by molecular imprinting utilizing noncovalent interactions. NMR and chromatographic studies on the nature of …
B Sellergren, M Lepistoe, K Mosbach
Journal of the American chemical society 110 (17), 5853-5860, 1988
7221988
Ligand binding mechanism in steroid receptors: from conserved plasticity to differential evolutionary constraints
K Edman, A Hosseini, MK Bjursell, A Aagaard, L Wissler, A Gunnarsson, ...
Structure 23 (12), 2280-2290, 2015
1072015
Novel conserved hydrolase domain in the CLCA family of alleged calcium‐activated chloride channels
K Pawłowski, M Lepistö, N Meinander, U Sivars, M Varga, E Wieslander
Proteins: Structure, Function, and Bioinformatics 63 (3), 424-439, 2006
802006
Discrimination between amino acid amide conformers by imprinted polymers
M Lepistoe, B Sellergren
The Journal of Organic Chemistry 54 (26), 6010-6012, 1989
721989
Discovery of a novel oral glucocorticoid receptor modulator (AZD9567) with improved side effect profile
L Ripa, K Edman, M Dearman, G Edenro, R Hendrickx, V Ullah, ...
Journal of Medicinal Chemistry 61 (5), 1785-1799, 2018
662018
Synthesis and functionalization of cyclic sulfonimidamides: a novel chiral heterocyclic carboxylic acid bioisostere
N Pemberton, H Graden, E Evertsson, E Bratt, M Lepistö, ...
ACS Medicinal Chemistry Letters 3 (7), 574-578, 2012
552012
Selective nonsteroidal glucocorticoid receptor modulators for the inhaled treatment of pulmonary diseases
M Hemmerling, S Nilsson, K Edman, S Eirefelt, W Russell, R Hendrickx, ...
Journal of Medicinal Chemistry 60 (20), 8591-8605, 2017
542017
Chemical Compounds 572
M Berger, J Dahmén, K Edman, A Eriksson, B Gabos, T Hansson, ...
US Patent App. 13/429,177, 2012
512012
HTS followed by NMR based counterscreening. Discovery and optimization of pyrimidones as reversible and competitive inhibitors of xanthine oxidase
J Evenäs, F Edfeldt, M Lepistö, N Svitacheva, A Synnergren, B Lundquist, ...
Bioorganic & Medicinal Chemistry Letters 24 (5), 1315-1321, 2014
382014
2-Pyridone derivatives as inhibitors of neutrophile elastase
H Bladh, T Klingstedt, J Larsson, K Lawitz, M Lepisto, H Lonn, G Nikitidis
US Patent App. 10/534,720, 2006
352006
The discovery of potent and selective non-steroidal glucocorticoid receptor modulators, suitable for inhalation
K Edman, R Ahlgren, M Bengtsson, H Bladh, S Bäckström, J Dahmén, ...
Bioorganic & medicinal chemistry letters 24 (11), 2571-2577, 2014
332014
Metalloproteinase inhibitors
A Eriksson, M Lepistö, M Lundkvist, MMA Rosenschöld, P Zlatoidsky
US Patent 7,427,631, 2008
332008
Dynamic allosteric communication pathway directing differential activation of the glucocorticoid receptor
C Köhler, G Carlström, A Gunnarsson, U Weininger, S Tångefjord, V Ullah, ...
Science Advances 6 (29), eabb5277, 2020
322020
Potent and orally bioavailable inverse agonists of RORγt resulting from structure-based design
F Narjes, Y Xue, S von Berg, J Malmberg, A Llinas, RI Olsson, J Jirholt, ...
Journal of Medicinal Chemistry 61 (17), 7796-7813, 2018
312018
Determination of the degree of derivatization of acryloylated polysaccharides by Fourier transform proton NMR spectroscopy
M Lepistö, P Artursson, P Edman, T Laakso, I Sjöholm
Analytical biochemistry 133 (1), 132-135, 1983
311983
Protein kinase inhibitors
K Karabelas, M Lepistö, P Sjö
US Patent 6,346,625, 2002
292002
Saccharin Aza Bioisosteres Synthesis and Preclinical Property Comparisons
Y Chen, CJ Aurell, A Pettersen, RJ Lewis, MA Hayes, M Lepistö, ...
ACS Medicinal Chemistry Letters 8 (6), 672-677, 2017
272017
Arrangement of pressure nozzles for the treatment of webs
M Lepisto
US Patent 4,932,140, 1990
251990
Metalloproteinase inhibitors
M Lepisto, MMA Rosenschold
US Patent App. 10/471,499, 2004
242004
The deubiquitinase USP7 uses a distinct ubiquitin-like domain to deubiquitinate NF-ĸB subunits
I Mitxitorena, D Somma, JP Mitchell, M Lepistö, C Tyrchan, EL Smith, ...
Journal of Biological Chemistry 295 (33), 11754-11763, 2020
232020
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Articles 1–20