| TGFβ: the molecular Jekyll and Hyde of cancer B Bierie, HL Moses Nature Reviews Cancer 6 (7), 506-520, 2006 | 1643 | 2006 |
| Recovering gene interactions from single-cell data using data diffusion D Van Dijk, R Sharma, J Nainys, K Yim, P Kathail, AJ Carr, C Burdziak, ... Cell 174 (3), 716-729. e27, 2018 | 1514 | 2018 |
| Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state CL Chaffer, I Brueckmann, C Scheel, AJ Kaestli, PA Wiggins, ... Proceedings of the National Academy of Sciences 108 (19), 7950-7955, 2011 | 1349 | 2011 |
| TGF-β and cancer B Bierie, HL Moses Cytokine & growth factor reviews 17 (1-2), 29-40, 2006 | 624 | 2006 |
| Acquisition of a hybrid E/M state is essential for tumorigenicity of basal breast cancer cells C Kröger, A Afeyan, J Mraz, EN Eaton, F Reinhardt, YL Khodor, P Thiru, ... Proceedings of the National Academy of Sciences 116 (15), 7353-7362, 2019 | 451 | 2019 |
| Transforming growth factor beta (TGF-β) and inflammation in cancer B Bierie, HL Moses Cytokine & growth factor reviews 21 (1), 49-59, 2010 | 443 | 2010 |
| The systemic response to surgery triggers the outgrowth of distant immune-controlled tumors in mouse models of dormancy JA Krall, F Reinhardt, OA Mercury, DR Pattabiraman, MW Brooks, ... Science translational medicine 10 (436), eaan3464, 2018 | 394 | 2018 |
| Protein kinase C α is a central signaling node and therapeutic target for breast cancer stem cells WL Tam, H Lu, J Buikhuisen, BS Soh, E Lim, F Reinhardt, ZJ Wu, JA Krall, ... Cancer cell 24 (3), 347-364, 2013 | 362 | 2013 |
| Activation of PKA leads to mesenchymal-to-epithelial transition and loss of tumor-initiating ability DR Pattabiraman, B Bierie, KI Kober, P Thiru, JA Krall, C Zill, F Reinhardt, ... Science 351 (6277), aad3680, 2016 | 343 | 2016 |
| Effect of conditional knockout of the type II TGF-β receptor gene in mammary epithelia on mammary gland development and polyomavirus middle T antigen induced tumor formation … E Forrester, A Chytil, B Bierie, M Aakre, AE Gorska, AR Sharif-Afshar, ... Cancer research 65 (6), 2296-2302, 2005 | 327 | 2005 |
| Integrin-β4 identifies cancer stem cell-enriched populations of partially mesenchymal carcinoma cells B Bierie, SE Pierce, C Kroeger, DG Stover, DR Pattabiraman, P Thiru, ... Proceedings of the National Academy of Sciences 114 (12), E2337-E2346, 2017 | 326 | 2017 |
| Inhibiting Cxcr2 disrupts tumor-stromal interactions and improves survival in a mouse model of pancreatic ductal adenocarcinoma H Ijichi, A Chytil, AE Gorska, ME Aakre, B Bierie, M Tada, D Mohri, ... The Journal of clinical investigation 121 (10), 4106-4117, 2011 | 290 | 2011 |
| Dihydropyrimidine accumulation is required for the epithelial-mesenchymal transition YD Shaul, E Freinkman, WC Comb, JR Cantor, WL Tam, P Thiru, D Kim, ... Cell 158 (5), 1094-1109, 2014 | 231 | 2014 |
| Predicting the response to CTLA-4 blockade by longitudinal noninvasive monitoring of CD8 T cells M Rashidian, JR Ingram, M Dougan, A Dongre, KA Whang, C LeGall, ... Journal of Experimental Medicine 214 (8), 2243-2255, 2017 | 229 | 2017 |
| A delicate balance: TGF‐β and the tumor microenvironment DG Stover, B Bierie, HL Moses Journal of cellular biochemistry 101 (4), 851-861, 2007 | 202 | 2007 |
| Abrogation of TGF-β signaling enhances chemokine production and correlates with prognosis in human breast cancer B Bierie, CH Chung, JS Parker, DG Stover, N Cheng, A Chytil, M Aakre, ... The Journal of clinical investigation 119 (6), 1571-1582, 2009 | 169 | 2009 |
| Deletion of Stat3 blocks mammary gland involution and extends functional competence of the secretory epithelium in the absence of lactogenic stimuli RC Humphreys, B Bierie, L Zhao, R Raz, D Levy, L Hennighausen Endocrinology 143 (9), 3641-3650, 2002 | 169 | 2002 |
| LACTB is a tumour suppressor that modulates lipid metabolism and cell state Z Keckesova, JL Donaher, J De Cock, E Freinkman, S Lingrell, ... Nature 543 (7647), 681-686, 2017 | 165 | 2017 |
| Activation of β-catenin in prostate epithelium induces hyperplasias and squamous transdifferentiation B Bierie, M Nozawa, JP Renou, JM Shillingford, F Morgan, T Oka, ... Oncogene 22 (25), 3875-3887, 2003 | 164 | 2003 |
| Transforming growth factor–β regulates mammary carcinoma cell survival and interaction with the adjacent microenvironment B Bierie, DG Stover, TW Abel, A Chytil, AE Gorska, M Aakre, E Forrester, ... Cancer research 68 (6), 1809-1819, 2008 | 161 | 2008 |
