| Evidence for a limit to human lifespan X Dong, B Milholland, J Vijg Nature 538 (7624), 257-259, 2016 | 551 | 2016 |
| Differences between germline and somatic mutation rates in humans and mice B Milholland, X Dong, L Zhang, X Hao, Y Suh, J Vijg Nature communications 8 (1), 15183, 2017 | 389 | 2017 |
| A Genome-Wide Association Study Identifies GRK5 and RASGRP1 as Type 2 Diabetes Loci in Chinese Hans H Li, W Gan, L Lu, X Dong, X Han, C Hu, Z Yang, L Sun, W Bao, P Li, ... Diabetes, 2012 | 223 | 2012 |
| Analysis of individual cells identifies cell‐to‐cell variability following induction of cellular senescence CD Wiley, JM Flynn, C Morrissey, R Lebofsky, J Shuga, X Dong, ... Aging cell 16 (5), 1043-1050, 2017 | 219 | 2017 |
| Accurate identification of single-nucleotide variants in whole-genome-amplified single cells X Dong, L Zhang, B Milholland, M Lee, AY Maslov, T Wang, J Vijg Nature Methods 201, 7, 2017 | 215 | 2017 |
| Single-cell whole-genome sequencing reveals the functional landscape of somatic mutations in B lymphocytes across the human lifespan L Zhang, X Dong, M Lee, AY Maslov, T Wang, J Vijg Proceedings of the National Academy of Sciences 116 (18), 9014-9019, 2019 | 203 | 2019 |
| Effects of smoking and smoking cessation on human serum metabolite profile: results from the KORA cohort study T Xu, C Holzapfel, X Dong, E Bader, Z Yu, C Prehn, K Perstorfer, ... BMC medicine 11, 1-14, 2013 | 137 | 2013 |
| Pathogenic mechanisms of somatic mutation and genome mosaicism in aging J Vijg, X Dong Cell 182 (1), 12-23, 2020 | 130 | 2020 |
| Single-cell genome-wide bisulfite sequencing uncovers extensive heterogeneity in the mouse liver methylome S Gravina, X Dong, B Yu, J Vijg Genome biology 17, 1-8, 2016 | 123 | 2016 |
| Prediction of deleterious non-synonymous SNPs based on protein interaction network and hybrid properties T Huang, P Wang, ZQ Ye, H Xu, Z He, KY Feng, LL Hu, WR Cui, K Wang, ... PLoS One 5 (7), e11900, 2010 | 94 | 2010 |
| Single-cell analysis reveals different age-related somatic mutation profiles between stem and differentiated cells in human liver K Brazhnik, S Sun, O Alani, M Kinkhabwala, AW Wolkoff, AY Maslov, ... Science Advances 6 (5), eaax2659, 2020 | 91 | 2020 |
| Genome-wide, single-cell DNA methylomics reveals increased non-CpG methylation during human oocyte maturation B Yu, X Dong, S Gravina, Ö Kartal, T Schimmel, J Cohen, D Tortoriello, ... Stem cell reports 9 (1), 397-407, 2017 | 90 | 2017 |
| Genetic evidence for common pathways in human age‐related diseases SC Johnson, X Dong, J Vijg, Y Suh Aging cell 14 (5), 809-817, 2015 | 90 | 2015 |
| Single-cell analysis of somatic mutations in human bronchial epithelial cells in relation to aging and smoking Z Huang, S Sun, M Lee, AY Maslov, M Shi, S Waldman, A Marsh, ... Nature genetics 54 (4), 492-498, 2022 | 56 | 2022 |
| Identification of hepatocellular carcinoma–related genes with a machine learning and network analysis T Gui, X Dong, R Li, Y Li, Z Wang Journal of Computational Biology 22 (1), 63-71, 2015 | 55 | 2015 |
| Epigenetics, DNA damage, and aging C Soto-Palma, LJ Niedernhofer, CD Faulk, X Dong The Journal of Clinical Investigation 132 (16), 2022 | 50 | 2022 |
| Genome instability: a conserved mechanism of ageing? J Vijg, X Dong, B Milholland, L Zhang Essays in biochemistry 61 (3), 305-315, 2017 | 47 | 2017 |
| A genome-wide study of allele-specific expression in colorectal cancer Z Liu, X Dong, Y Li Frontiers in Genetics 9, 570, 2018 | 33 | 2018 |
| Maintenance of genome sequence integrity in long-and short-lived rodent species L Zhang, X Dong, X Tian, M Lee, J Ablaeva, D Firsanov, SG Lee, ... Science Advances 7 (44), eabj3284, 2021 | 29 | 2021 |
| Development of a method to implement whole-genome bisulfite sequencing of cfDNA from cancer patients and a mouse tumor model EC Maggi, S Gravina, H Cheng, B Piperdi, Z Yuan, X Dong, SK Libutti, ... Frontiers in genetics 9, 6, 2018 | 25 | 2018 |
Lei ZhangUniversity of MinnesotaVerified email at umn.edu
