Brian Helfand
Brian Helfand
Clinical Associate Professor, NorthShore University HealthSystem
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A specific mechanism of nonspecific inhibition
SL McGovern, BT Helfand, B Feng, BK Shoichet
Journal of medicinal chemistry 46 (20), 4265-4272, 2003
Introducing intermediate filaments: from discovery to disease
JE Eriksson, T Dechat, B Grin, B Helfand, M Mendez, HM Pallari, ...
The Journal of clinical investigation 119 (7), 1763-1771, 2009
Common sequence variants on 2p15 and Xp11. 22 confer susceptibility to prostate cancer
J Gudmundsson, P Sulem, T Rafnar, JT Bergthorsson, A Manolescu, ...
Nature genetics 40 (3), 281-283, 2008
Genome-wide association and replication studies identify four variants associated with prostate cancer susceptibility
J Gudmundsson, P Sulem, DF Gudbjartsson, T Blondal, A Gylfason, ...
Nature genetics 41 (10), 1122-1126, 2009
Intermediate filaments are dynamic and motile elements of cellular architecture
BT Helfand, L Chang, RD Goldman
Journal of cell science 117 (2), 133-141, 2004
Germline mutations in ATM and BRCA1/2 distinguish risk for lethal and indolent prostate cancer and are associated with early age at death
R Na, SL Zheng, M Han, H Yu, D Jiang, S Shah, CM Ewing, L Zhang, ...
European urology 71 (5), 740-747, 2017
A germline variant in the TP53 polyadenylation signal confers cancer susceptibility
SN Stacey, P Sulem, A Jonasdottir, G Masson, J Gudmundsson, ...
Nature genetics 43 (11), 1098-1103, 2011
Vimentin organization modulates the formation of lamellipodia
BT Helfand, MG Mendez, SNP Murthy, DK Shumaker, B Grin, ...
Molecular biology of the cell 22 (8), 1274-1289, 2011
A study based on whole-genome sequencing yields a rare variant at 8q24 associated with prostate cancer
J Gudmundsson, P Sulem, DF Gudbjartsson, G Masson, BA Agnarsson, ...
Nature genetics 44 (12), 1326-1329, 2012
A requirement for cytoplasmic dynein and dynactin in intermediate filament network assembly and organization
BT Helfand, A Mikami, RB Vallee, RD Goldman
The Journal of cell biology 157 (5), 795-806, 2002
Implementation of germline testing for prostate cancer: Philadelphia Prostate Cancer Consensus Conference 2019
VN Giri, KE Knudsen, WK Kelly, HH Cheng, KA Cooney, MS Cookson, ...
Journal of Clinical Oncology 38 (24), 2798, 2020
Established medical therapy for benign prostatic hyperplasia
GB Auffenberg, BT Helfand, KT McVary
Urologic Clinics 36 (4), 443-459, 2009
Genetic correction of PSA values using sequence variants associated with PSA levels
J Gudmundsson, S Besenbacher, P Sulem, DF Gudbjartsson, I Olafsson, ...
Science translational medicine 2 (62), 62ra92-62ra92, 2010
Interim results from the IMPACT study: evidence for prostate-specific antigen screening in BRCA2 mutation carriers
EC Page, EK Bancroft, MN Brook, M Assel, MH Al Battat, S Thomas, ...
European urology 76 (6), 831-842, 2019
Germline mutations in ATM and BRCA1/2 are associated with grade reclassification in men on active surveillance for prostate cancer
HB Carter, B Helfand, M Mamawala, Y Wu, P Landis, H Yu, K Wiley, R Na, ...
European urology 75 (5), 743-749, 2019
Biomimetic high density lipoprotein nanoparticles for nucleic acid delivery
KM McMahon, RK Mutharasan, S Tripathy, D Veliceasa, M Bobeica, ...
Nano letters 11 (3), 1208-1214, 2011
A role for intermediate filaments in determining and maintaining the shape of nerve cells
BT Helfand, MG Mendez, J Pugh, C Delsert, RD Goldman
Molecular biology of the cell 14 (12), 5069-5081, 2003
Fast transport of neurofilament protein along microtubules in squid axoplasm
V Prahlad, BT Helfand, GM Langford, RD Vale, RD Goldman
Journal of Cell Science 113 (22), 3939-3946, 2000
Nuclear factor-κB-mediated transforming growth factor-β-induced expression of vimentin is an independent predictor of biochemical recurrence after radical prostatectomy
Q Zhang, BT Helfand, TL Jang, LJ Zhu, L Chen, XJ Yang, J Kozlowski, ...
Clinical cancer research 15 (10), 3557-3567, 2009
The dynamic and motile properties of intermediate filaments
BT Helfand, L Chang, RD Goldman
Annual review of cell and developmental biology 19 (1), 445-467, 2003
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