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Christine Feig
Christine Feig
Project manager (drug development)
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Year
Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer
KP Olive, MA Jacobetz, CJ Davidson, A Gopinathan, D McIntyre, ...
Science 324 (5933), 1457-1461, 2009
35182009
Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer
D Öhlund, A Handly-Santana, G Biffi, E Elyada, AS Almeida, ...
Journal of Experimental Medicine 214 (3), 579-596, 2017
19172017
Targeting CXCL12 from FAP-expressing carcinoma-associated fibroblasts synergizes with anti–PD-L1 immunotherapy in pancreatic cancer
C Feig, JO Jones, M Kraman, RJB Wells, A Deonarine, DS Chan, ...
Proceedings of the National Academy of Sciences 110 (50), 20212-20217, 2013
17852013
The pancreas cancer microenvironment
C Feig, A Gopinathan, A Neesse, DS Chan, N Cook, DA Tuveson
Clinical cancer research 18 (16), 4266-4276, 2012
13872012
Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer
MA Jacobetz, DS Chan, A Neesse, TE Bapiro, N Cook, KK Frese, C Feig, ...
Gut 62 (1), 112-120, 2013
11112013
Stromal biology and therapy in pancreatic cancer
A Neesse, P Michl, KK Frese, C Feig, N Cook, MA Jacobetz, MP Lolkema, ...
Gut 60 (6), 861-868, 2011
8922011
International Cancer of the Pancreas Screening (CAPS) Consortium summit on the management of patients with increased risk for familial pancreatic cancer
MI Canto, F Harinck, RH Hruban, GJ Offerhaus, JW Poley, I Kamel, Y Nio, ...
Gut 62 (3), 339-347, 2013
8392013
Let-7 expression defines two differentiation stages of cancer
S Shell, SM Park, AR Radjabi, R Schickel, EO Kistner, DA Jewell, C Feig, ...
Proceedings of the National Academy of Sciences 104 (27), 11400-11405, 2007
5992007
CD95 promotes tumour growth
L Chen, SM Park, AV Tumanov, A Hau, K Sawada, C Feig, JR Turner, ...
Nature 465 (7297), 492-496, 2010
4582010
Retinoic acid–induced pancreatic stellate cell quiescence reduces paracrine Wnt–β-catenin signaling to slow tumor progression
FEM Froeling, C Feig, C Chelala, R Dobson, CE Mein, DA Tuveson, ...
Gastroenterology 141 (4), 1486-1497. e14, 2011
4062011
Depletion of stromal cells expressing fibroblast activation protein-α from skeletal muscle and bone marrow results in cachexia and anemia
EW Roberts, A Deonarine, JO Jones, AE Denton, C Feig, SK Lyons, ...
Journal of Experimental Medicine 210 (6), 1137-1151, 2013
3782013
Let-7 prevents early cancer progression by suppressing expression of the embryonic gene HMGA2
SM Park, S Shell, AR Radjabi, R Schickel, C Feig, B Boyerinas, ...
Cell cycle 6 (21), 2585-2590, 2007
3142007
The role of receptor internalization in CD95 signaling
KH Lee, C Feig, V Tchikov, R Schickel, C Hallas, S Schütze, ME Peter, ...
The EMBO journal 25 (5), 1009-1023, 2006
2982006
Identification of let-7–regulated oncofetal genes
B Boyerinas, SM Park, N Shomron, MM Hedegaard, J Vinther, ...
Cancer research 68 (8), 2587-2591, 2008
2902008
Palmitoylation of CD95 facilitates formation of SDS‐stable receptor aggregates that initiate apoptosis signaling
C Feig, V Tchikov, S Schütze, ME Peter
The EMBO journal 26 (1), 221-231, 2007
1912007
Phosphorylation of FADD at serine 194 by CKIα regulates its nonapoptotic activities
EC Alappat, C Feig, B Boyerinas, J Volkland, M Samuels, AE Murmann, ...
Molecular cell 19 (3), 321-332, 2005
1732005
egc-Encoded Superantigens from Staphylococcus aureus Are Neutralized by Human Sera Much Less Efficiently than Are Classical Staphylococcal Enterotoxins or …
S Holtfreter, K Bauer, D Thomas, C Feig, V Lorenz, K Roschack, E Friebe, ...
Infection and immunity 72 (7), 4061-4071, 2004
1642004
Anti‐stromal treatment together with chemotherapy targets multiple signalling pathways in pancreatic adenocarcinoma
EF Carapuça, E Gemenetzidis, C Feig, TE Bapiro, MD Williams, ...
The Journal of pathology 239 (3), 286-296, 2016
1242016
How apoptosis got the immune system in shape
C Feig, ME Peter
European journal of immunology 37 (S1), S61-S70, 2007
1212007
Mutational landscape of a chemically-induced mouse model of liver cancer
F Connor, TF Rayner, SJ Aitken, C Feig, M Lukk, J Santoyo-Lopez, ...
Journal of hepatology 69 (4), 840-850, 2018
1192018
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