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Dora Dias-Santagata
Dora Dias-Santagata
Harvard Medical School, Massachusetts General Hospital
Bestätigte E-Mail-Adresse bei mgh.harvard.edu
Titel
Zitiert von
Zitiert von
Jahr
Genotypic and histological evolution of lung cancers acquiring resistance to EGFR inhibitors
LV Sequist, BA Waltman, D Dias-Santagata, S Digumarthy, AB Turke, ...
Science translational medicine 3 (75), 75ra26-75ra26, 2011
36502011
Preexistence and clonal selection of MET amplification in EGFR mutant NSCLC
AB Turke, K Zejnullahu, YL Wu, Y Song, D Dias-Santagata, E Lifshits, ...
Cancer cell 17 (1), 77-88, 2010
12242010
Molecular Mechanisms of Resistance to First- and Second-Generation ALK Inhibitors in ALK-Rearranged Lung Cancer
JF Gainor, L Dardaei, S Yoda, L Friboulet, I Leshchiner, R Katayama, ...
Cancer discovery 6 (10), 1118-1133, 2016
11002016
EGFR-Mediated Reactivation of MAPK Signaling Contributes to Insensitivity of BRAF-Mutant Colorectal Cancers to RAF Inhibition with Vemurafenib
RB Corcoran, H Ebi, AB Turke, EM Coffee, M Nishino, AP Cogdill, ...
Cancer discovery 2 (3), 227-235, 2012
11002012
Frequent Mutation of Isocitrate Dehydrogenase (IDH)1 and IDH2 in Cholangiocarcinoma Identified Through Broad-Based Tumor Genotyping
DR Borger, KK Tanabe, KC Fan, HU Lopez, VR Fantin, KS Straley, ...
The oncologist 17 (1), 72-79, 2012
8102012
ALK Rearrangements Are Mutually Exclusive with Mutations in EGFR or KRAS: An Analysis of 1,683 Patients with Non–Small Cell Lung Cancer
JF Gainor, AM Varghese, SHI Ou, S Kabraji, MM Awad, R Katayama, ...
Clinical cancer research 19 (15), 4273-4281, 2013
6352013
Elevated CRAF as a potential mechanism of acquired resistance to BRAF inhibition in melanoma
C Montagut, SV Sharma, T Shioda, U McDermott, M Ulman, LE Ulkus, ...
Cancer research 68 (12), 4853-4861, 2008
6162008
Lung cancers with acquired resistance to EGFR inhibitors occasionally harbor BRAF gene mutations but lack mutations in KRAS, NRAS, or MEK1
K Ohashi, LV Sequist, ME Arcila, T Moran, J Chmielecki, YL Lin, Y Pan, ...
Proceedings of the National Academy of Sciences 109 (31), E2127-E2133, 2012
5092012
Heterogeneity Underlies the Emergence of EGFRT790 Wild-Type Clones Following Treatment of T790M-Positive Cancers with a Third-Generation EGFR Inhibitor
Z Piotrowska, MJ Niederst, CA Karlovich, HA Wakelee, JW Neal, ...
Cancer discovery 5 (7), 713-722, 2015
5012015
Nedd8 on cullin: building an expressway to protein destruction
ZQ Pan, A Kentsis, DC Dias, K Yamoah, K Wu
Oncogene 23 (11), 1985-1997, 2004
4912004
Implementing multiplexed genotyping of non-small-cell lung cancers into routine clinical practice
LV Sequist, RS Heist, AT Shaw, P Fidias, R Rosovsky, JS Temel, ...
Annals of Oncology 22 (12), 2616-2624, 2011
4702011
Exome sequencing identifies BRAF mutations in papillary craniopharyngiomas
PK Brastianos, A Taylor-Weiner, PE Manley, RT Jones, D Dias-Santagata, ...
Nature genetics 46 (2), 161-165, 2014
4572014
Multi-institutional oncogenic driver mutation analysis in lung adenocarcinoma: the lung cancer mutation consortium experience
LM Sholl, DL Aisner, M Varella-Garcia, LD Berry, D Dias-Santagata, ...
Journal of thoracic oncology 10 (5), 768-777, 2015
4422015
BRAF gene amplification can promote acquired resistance to MEK inhibitors in cancer cells harboring the BRAF V600E mutation
RB Corcoran, D Dias-Santagata, K Bergethon, AJ Iafrate, J Settleman, ...
Science signaling 3 (149), ra84-ra84, 2010
4212010
Rapid targeted mutational analysis of human tumours: a clinical platform to guide personalized cancer medicine
D Dias‐Santagata, S Akhavanfard, SS David, K Vernovsky, G Kuhlmann, ...
EMBO molecular medicine 2 (5), 146-158, 2010
4122010
Synthetic lethal interaction of combined BCL-XL and MEK inhibition promotes tumor regressions in KRAS mutant cancer models
RB Corcoran, KA Cheng, AN Hata, AC Faber, H Ebi, EM Coffee, ...
Cancer cell 23 (1), 121-128, 2013
4052013
Liquid versus tissue biopsy for detecting acquired resistance and tumor heterogeneity in gastrointestinal cancers
AR Parikh, I Leshchiner, L Elagina, L Goyal, C Levovitz, G Siravegna, ...
Nature medicine 25 (9), 1415-1421, 2019
4022019
Landscape of Acquired Resistance to Osimertinib in EGFR-Mutant NSCLC and Clinical Validation of Combined EGFR and RET Inhibition with Osimertinib and BLU-667 for …
Z Piotrowska, H Isozaki, JK Lennerz, JF Gainor, IT Lennes, VW Zhu, ...
Cancer discovery 8 (12), 1529-1539, 2018
3842018
The reprogramming of tumor stroma by HSF1 is a potent enabler of malignancy
R Scherz-Shouval, S Santagata, ML Mendillo, LM Sholl, I Ben-Aharon, ...
Cell 158 (3), 564-578, 2014
3802014
BRAF V600E mutations are common in pleomorphic xanthoastrocytoma: diagnostic and therapeutic implications
D Dias-Santagata, Q Lam, K Vernovsky, N Vena, JK Lennerz, DR Borger, ...
PloS one 6 (3), e17948, 2011
3602011
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