| Shiga toxin activates complement and binds factor H: evidence for an active role of complement in hemolytic uremic syndrome D Orth, AB Khan, A Naim, K Grif, J Brockmeyer, H Karch, M Joannidis, ... The Journal of Immunology 182 (10), 6394-6400, 2009 | 264 | 2009 |
| Structural basis for complement factor H–linked age-related macular degeneration BE Prosser, S Johnson, P Roversi, AP Herbert, BS Blaum, J Tyrrell, ... The Journal of experimental medicine 204 (10), 2277-2283, 2007 | 206 | 2007 |
| Impaired binding of the age-related macular degeneration-associated complement factor H 402H allotype to Bruch's membrane in human retina SJ Clark, R Perveen, S Hakobyan, BP Morgan, RB Sim, PN Bishop, ... Journal of biological chemistry 285 (39), 30192-30202, 2010 | 203 | 2010 |
| His-384 allotypic variant of factor H associated with age-related macular degeneration has different heparin binding properties from the non-disease-associated form SJ Clark, VA Higman, B Mulloy, SJ Perkins, SM Lea, RB Sim, AJ Day Journal of biological chemistry 281 (34), 24713-24720, 2006 | 201 | 2006 |
| Complement factor H in host defense and immune evasion R Parente, SJ Clark, A Inforzato, AJ Day Cellular and Molecular Life Sciences 74, 1605-1624, 2017 | 174 | 2017 |
| Tissue-specific host recognition by complement factor H is mediated by differential activities of its glycosaminoglycan-binding regions SJ Clark, LA Ridge, AP Herbert, S Hakobyan, B Mulloy, R Lennon, ... The Journal of Immunology 190 (5), 2049-2057, 2013 | 171 | 2013 |
| Shift from coral to macroalgae dominance on a volcanically acidified reef IC Enochs, DP Manzello, EM Donham, G Kolodziej, R Okano, L Johnston, ... Nature Climate Change 5 (12), 1083-1088, 2015 | 170 | 2015 |
| Age-related macular degeneration: genome-wide association studies to translation JRM Black, SJ Clark Genetics in Medicine 18 (4), 283-289, 2016 | 165 | 2016 |
| The factor H variant associated with age-related macular degeneration (His-384) and the non-disease-associated form bind differentially to C-reactive protein, fibromodulin, DNA … AP Sjoberg, LA Trouw, SJ Clark, J Sjolander, D Heinegard, RB Sim, ... Journal of Biological Chemistry 282 (15), 10894-10900, 2007 | 151 | 2007 |
| Age-related macular degeneration and the role of the complement system S McHarg, SJ Clark, AJ Day, PN Bishop Molecular immunology 67 (1), 43-50, 2015 | 135 | 2015 |
| Genetic variants in the complement system predisposing to age-related macular degeneration: a review EC Schramm, SJ Clark, MP Triebwasser, S Raychaudhuri, JM Seddon, ... Molecular immunology 61 (2), 118-125, 2014 | 131 | 2014 |
| Identification of factor H–like protein 1 as the predominant complement regulator in Bruch’s membrane: Implications for age-related macular degeneration SJ Clark, CQ Schmidt, AM White, S Hakobyan, BP Morgan, PN Bishop The Journal of Immunology 193 (10), 4962-4970, 2014 | 128 | 2014 |
| The complement system in age-related macular degeneration A Armento, M Ueffing, SJ Clark Cellular and Molecular Life Sciences 78, 4487-4505, 2021 | 120 | 2021 |
| Mapping the differential distribution of glycosaminoglycans in the adult human retina, choroid, and sclera SJ Clark, TDL Keenan, HL Fielder, LJ Collinson, RJ Holley, CLR Merry, ... Investigative ophthalmology & visual science 52 (9), 6511-6521, 2011 | 118 | 2011 |
| Complement factor H and age-related macular degeneration: the role of glycosaminoglycan recognition in disease pathology SJ Clark, PN Bishop, AJ Day Biochemical Society Transactions 38 (5), 1342-1348, 2010 | 107 | 2010 |
| The eye as a complement dysregulation hotspot SJ Clark, PN Bishop Seminars in immunopathology 40 (1), 65-74, 2018 | 99 | 2018 |
| Mapping the differential distribution of proteoglycan core proteins in the adult human retina, choroid, and sclera TDL Keenan, SJ Clark, RD Unwin, LA Ridge, AJ Day, PN Bishop Investigative ophthalmology & visual science 53 (12), 7528-7538, 2012 | 93 | 2012 |
| Complementing the sugar code: role of GAGs and sialic acid in complement regulation A Langford-Smith, AJ Day, PN Bishop, SJ Clark Frontiers in immunology 6, 129222, 2015 | 92 | 2015 |
| Increased circulating levels of Factor H-Related Protein 4 are strongly associated with age-related macular degeneration V Cipriani, L Lorés-Motta, F He, D Fathalla, V Tilakaratna, S McHarg, ... Nature communications 11 (1), 778, 2020 | 86 | 2020 |
| The role of complement in age-related macular degeneration: heparan sulphate, a ZIP code for complement factor H? A Langford-Smith, TDL Keenan, SJ Clark, PN Bishop, AJ Day Journal of innate immunity 6 (4), 407-416, 2014 | 73 | 2014 |
Anthony J. DayProfessor of Biochemistry, University of Manchester, UKVerified email at manchester.ac.uk
