Ernst Hafen
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Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein
DJ Clancy, D Gems, LG Harshman, S Oldham, H Stocker, E Hafen, ...
Science 292 (5514), 104-106, 2001
Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex
J Brugarolas, K Lei, RL Hurley, BD Manning, JH Reiling, E Hafen, ...
Genes & development 18 (23), 2893-2904, 2004
An evolutionarily conserved function of the Drosophila insulin receptor and insulin-like peptides in growth control
W Brogiolo, H Stocker, T Ikeya, F Rintelen, R Fernandez, E Hafen
Current biology 11 (4), 213-221, 2001
A conserved DNA sequence in homoeotic genes of the Drosophila Antennapedia and bithorax complexes
W McGinnis, MS Levine, E Hafen, A Kuroiwa, WJ Gehring
Nature 308 (5958), 428-433, 1984
Insulin activation of Rheb, a mediator of mTOR/S6K/4E-BP signaling, is inhibited by TSC1 and 2
A Garami, FJT Zwartkruis, T Nobukuni, M Joaquin, M Roccio, H Stocker, ...
Molecular cell 11 (6), 1457-1466, 2003
Autonomous control of cell and organ size by CHICO, a Drosophila homolog of vertebrate IRS1–4
R Böhni, J Riesgo-Escovar, S Oldham, W Brogiolo, H Stocker, BF Andruss, ...
Cell 97 (7), 865-875, 1999
Longer lifespan, altered metabolism, and stress resistance in Drosophila from ablation of cells making insulin-like ligands
SJ Broughton, MDW Piper, T Ikeya, TM Bass, J Jacobson, Y Driege, ...
Proceedings of the National Academy of Sciences 102 (8), 3105-3110, 2005
Drosophila S6 kinase: a regulator of cell size
J Montagne, MJ Stewart, H Stocker, E Hafen, SC Kozma, G Thomas
Science 285 (5436), 2126-2129, 1999
Nutrient-dependent expression of insulin-like peptides from neuroendocrine cells in the CNS contributes to growth regulation in Drosophila
T Ikeya, M Galic, P Belawat, K Nairz, E Hafen
Current biology 12 (15), 1293-1300, 2002
Long-Lived Drosophila with Overexpressed dFOXO in Adult Fat Body
ME Giannakou, M Goss, MA Junger, E Hafen, SJ Leevers, L Partridge
Science 305 (5682), 361-361, 2004
A Drosophila SH2-SH3 adaptor protein implicated in coupling the sevenless tyrosine kinase to an activator of Ras guanine nucleotide exchange, Sos
JP Olivier, T Raabe, M Henkemeyer, B Dickson, G Mbamalu, B Margolis, ...
Cell 73 (1), 179-191, 1993
Dispatched, a novel sterol-sensing domain protein dedicated to the release of cholesterol-modified hedgehog from signaling cells
R Burke, D Nellen, M Bellotto, E Hafen, KA Senti, BJ Dickson, K Basler
Cell 99 (7), 803-815, 1999
The Drosophila Forkhead transcription factor FOXO mediates the reduction in cell number associated with reduced insulin signaling
MA Jünger, F Rintelen, H Stocker, JD Wasserman, M Végh, T Radimerski, ...
Journal of biology 2, 1-17, 2003
Insulin/IGF and target of rapamycin signaling: a TOR de force in growth control
S Oldham, E Hafen
Trends in cell biology 13 (2), 79-85, 2003
Rheb is an essential regulator of S6K in controlling cell growth in Drosophila
H Stocker, T Radimerski, B Schindelholz, F Wittwer, P Belawat, P Daram, ...
Nature cell biology 5 (6), 559-566, 2003
The Drosophila phosphoinositide 3‐kinase Dp110 promotes cell growth.
SJ Leevers, D Weinkove, LK MacDougall, E Hafen, MD Waterfield
The EMBO journal 15 (23), 6584-6594, 1996
Genetic and biochemical characterization of dTOR, the Drosophila homolog of the target of rapamycin
S Oldham, J Montagne, T Radimerski, G Thomas, E Hafen
Genes & development 14 (21), 2689-2694, 2000
Will democracy survive big data and artificial intelligence?
D Helbing, BS Frey, G Gigerenzer, E Hafen, M Hagner, Y Hofstetter, ...
Towards digital enlightenment: Essays on the dark and light sides of the …, 2019
A gain-of-function mutation in Drosophila MAP kinase activates multiple receptor tyrosine kinase signaling pathways
D Brunner, N Oellers, J Szabad, WH Biggs III, SL Zipursky, E Hafen
Cell 76 (5), 875-888, 1994
Sevenless, a cell-specific homeotic gene of Drosophila, encodes a putative transmembrane receptor with a tyrosine kinase domain
E Hafen, K Basler, JE Edstroem, GM Rubin
Science 236 (4797), 55-63, 1987
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Articles 1–20