Ligand-directed tosyl chemistry for protein labeling in vivo S Tsukiji, M Miyagawa, Y Takaoka, T Tamura, I Hamachi Nature chemical biology 5 (5), 341-343, 2009 | 380 | 2009 |
Protein organic chemistry and applications for labeling and engineering in live‐cell systems Y Takaoka, A Ojida, I Hamachi Angewandte Chemie International Edition 52 (15), 4088-4106, 2013 | 327 | 2013 |
Self-assembling nanoprobes that display off/on 19F nuclear magnetic resonance signals for protein detection and imaging Y Takaoka, T Sakamoto, S Tsukiji, M Narazaki, T Matsuda, H Tochio, ... Nature chemistry 1 (7), 557-561, 2009 | 223 | 2009 |
Specific cell surface protein imaging by extended self-assembling fluorescent turn-on nanoprobes K Mizusawa, Y Takaoka, I Hamachi Journal of the American Chemical Society 134 (32), 13386-13395, 2012 | 169 | 2012 |
One-pot and sequential organic chemistry on an enzyme surface to tether a fluorescent probe at the proximity of the active site with restoring enzyme activity Y Takaoka, H Tsutsumi, N Kasagi, E Nakata, I Hamachi Journal of the American Chemical Society 128 (10), 3273-3280, 2006 | 151 | 2006 |
Disassembly-driven turn-on fluorescent nanoprobes for selective protein detection K Mizusawa, Y Ishida, Y Takaoka, M Miyagawa, S Tsukiji, I Hamachi Journal of the American Chemical Society 132 (21), 7291-7293, 2010 | 120 | 2010 |
Quenched ligand-directed tosylate reagents for one-step construction of turn-on fluorescent biosensors S Tsukiji, H Wang, M Miyagawa, T Tamura, Y Takaoka, I Hamachi Journal of the American Chemical Society 131 (25), 9046-9054, 2009 | 97 | 2009 |
Ligand-directed dibromophenyl benzoate chemistry for rapid and selective acylation of intracellular natural proteins Y Takaoka, Y Nishikawa, Y Hashimoto, K Sasaki, I Hamachi Chemical Science 6 (5), 3217-3224, 2015 | 91 | 2015 |
Acidic‐pH‐activatable fluorescence probes for visualizing exocytosis dynamics D Asanuma, Y Takaoka, S Namiki, K Takikawa, M Kamiya, T Nagano, ... Angewandte Chemie International Edition 53 (24), 6085-6089, 2014 | 87 | 2014 |
Systematic Study of Protein Detection Mechanism of Self-Assembling 19F NMR/MRI Nanoprobes toward Rational Design and Improved Sensitivity Y Takaoka, K Kiminami, K Mizusawa, K Matsuo, M Narazaki, T Matsuda, ... Journal of the American Chemical Society 133 (30), 11725-11731, 2011 | 83 | 2011 |
Intracellular protein-responsive supramolecules: protein sensing and in-cell construction of inhibitor assay system T Yoshii, K Mizusawa, Y Takaoka, I Hamachi Journal of the American Chemical Society 136 (47), 16635-16642, 2014 | 62 | 2014 |
Analysis of cell-surface receptor dynamics through covalent labeling by catalyst-tethered antibody T Hayashi, Y Yasueda, T Tamura, Y Takaoka, I Hamachi Journal of the American Chemical Society 137 (16), 5372-5380, 2015 | 61 | 2015 |
A rationally designed JAZ subtype-selective agonist of jasmonate perception Y Takaoka, M Iwahashi, A Chini, H Saito, Y Ishimaru, S Egoshi, N Kato, ... Nature Communications 9 (1), 3654, 2018 | 54 | 2018 |
Quantitative comparison of protein dynamics in live cells and in vitro by in-cell 19 F-NMR Y Takaoka, Y Kioi, A Morito, J Otani, K Arita, E Ashihara, M Ariyoshi, ... Chemical communications 49 (27), 2801-2803, 2013 | 53 | 2013 |
Semisynthetic lectin–4-dimethylaminopyridine conjugates for labeling and profiling glycoproteins on live cell surfaces T Hayashi, Y Sun, T Tamura, K Kuwata, Z Song, Y Takaoka, I Hamachi Journal of the American Chemical Society 135 (33), 12252-12258, 2013 | 50 | 2013 |
Organische Proteinchemie und ihre Anwendung für Markierungen und Engineering in Lebendzellsystemen Y Takaoka, A Ojida, I Hamachi Angewandte Chemie 125 (15), 4182-4200, 2013 | 49 | 2013 |
One-step construction of caged carbonic anhydrase I using a ligand-directed acyl imidazole-based protein labeling method K Matsuo, Y Kioi, R Yasui, Y Takaoka, T Miki, S Fujishima, I Hamachi Chemical Science 4 (6), 2573-2580, 2013 | 49 | 2013 |
Specific Detection and Imaging of Enzyme Activity by Signal‐Amplifiable Self‐Assembling 19F MRI Probes K Matsuo, R Kamada, K Mizusawa, H Imai, Y Takayama, M Narazaki, ... Chemistry–A European Journal 19 (38), 12875-12883, 2013 | 43 | 2013 |
Mechanisms of chemical protein 19 F-labeling and NMR-based biosensor construction in vitro and in cells using self-assembling ligand-directed tosylate compounds Y Takaoka, Y Sun, S Tsukiji, I Hamachi Chemical Science 2 (3), 511-520, 2011 | 41 | 2011 |
Affinity‐labeling‐based introduction of a reactive handle for natural protein modification H Wakabayashi, M Miyagawa, Y Koshi, Y Takaoka, S Tsukiji, I Hamachi Chemistry–An Asian Journal 3 (7), 1134-1139, 2008 | 40 | 2008 |