Ovarian cancer side population defines cells with stem cell-like characteristics and Mullerian Inhibiting Substance responsiveness PP Szotek, R Pieretti-Vanmarcke, PT Masiakos, DM Dinulescu, ... Proceedings of the National Academy of Sciences 103 (30), 11154-11159, 2006 | 962 | 2006 |
Integration of NPY, AGRP, and melanocortin signals in the hypothalamic paraventricular nucleus: evidence of a cellular basis for the adipostat MA Cowley, N Pronchuk, W Fan, DM Dinulescu, WF Colmers, RD Cone Neuron 24 (1), 155-163, 1999 | 764 | 1999 |
Role of K-ras and Pten in the development of mouse models of endometriosis and endometrioid ovarian cancer DM Dinulescu, TA Ince, BJ Quade, SA Shafer, D Crowley, T Jacks Nature medicine 11 (1), 63-70, 2005 | 714 | 2005 |
Transformation of the fallopian tube secretory epithelium leads to high-grade serous ovarian cancer in Brca; Tp53; Pten models R Perets, GA Wyant, KW Muto, JG Bijron, BB Poole, KT Chin, JYH Chen, ... Cancer cell 24 (6), 751-765, 2013 | 603 | 2013 |
Targeting Notch, a key pathway for ovarian cancer stem cells, sensitizes tumors to platinum therapy SM McAuliffe, SL Morgan, GA Wyant, LT Tran, KW Muto, YS Chen, ... Proceedings of the National Academy of Sciences 109 (43), E2939-E2948, 2012 | 370 | 2012 |
The central melanocortin system can directly regulate serum insulin levels W Fan, DM Dinulescu, AA Butler, J Zhou, DL Marks, RD Cone Endocrinology 141 (9), 3072-3079, 2000 | 359 | 2000 |
A spatially and temporally restricted mouse model of soft tissue sarcoma DG Kirsch, DM Dinulescu, JB Miller, J Grimm, PM Santiago, NP Young, ... Nature medicine 13 (8), 992-997, 2007 | 342 | 2007 |
Let-7 prevents early cancer progression by suppressing expression of the embryonic gene HMGA2 SM Park, S Shell, AR Radjabi, R Schickel, C Feig, B Boyerinas, ... Cell cycle 6 (21), 2585-2590, 2007 | 314 | 2007 |
Enzyme‐instructed intracellular molecular self‐assembly to boost activity of cisplatin against drug‐resistant ovarian cancer cells J Li, Y Kuang, J Shi, J Zhou, JE Medina, R Zhou, D Yuan, C Yang, ... Angewandte Chemie International Edition 54 (45), 13307-13311, 2015 | 186 | 2015 |
Agouti and agouti-related protein: analogies and contrasts DM Dinulescu, RD Cone Journal of Biological Chemistry 275 (10), 6695-6698, 2000 | 183 | 2000 |
Lung cancer signatures in plasma based on proteome profiling of mouse tumor models A Taguchi, K Politi, SJ Pitteri, WW Lockwood, VM Faça, K Kelly-Spratt, ... Cancer cell 20 (3), 289-299, 2011 | 178 | 2011 |
Genetic models of obesity and energy balance in the mouse SW Robinson, DM Dinulescu, RD Cone Annual review of genetics 34 (1), 687-745, 2000 | 161 | 2000 |
Cholesterol-tethered platinum II-based supramolecular nanoparticle increases antitumor efficacy and reduces nephrotoxicity P Sengupta, S Basu, S Soni, A Pandey, B Roy, MS Oh, KT Chin, ... Proceedings of the National Academy of Sciences 109 (28), 11294-11299, 2012 | 150 | 2012 |
Harnessing structure-activity relationship to engineer a cisplatin nanoparticle for enhanced antitumor efficacy AS Paraskar, S Soni, KT Chin, P Chaudhuri, KW Muto, J Berkowitz, ... Proceedings of the National Academy of Sciences 107 (28), 12435-12440, 2010 | 150 | 2010 |
Focused glycomic analysis of the N‐linked glycan biosynthetic pathway in ovarian cancer KL Abbott, AV Nairn, EM Hall, MB Horton, JF McDonald, KW Moremen, ... Proteomics 8 (16), 3210-3220, 2008 | 135 | 2008 |
Mahogany (mg) stimulates feeding and increases basal metabolic rate independent of its suppression of agouti DM Dinulescu, W Fan, BA Boston, K McCall, ML Lamoreux, KJ Moore, ... Proceedings of the National Academy of Sciences 95 (21), 12707-12712, 1998 | 113 | 1998 |
Cyclooxygenase-1 is overexpressed in multiple genetically engineered mouse models of epithelial ovarian cancer T Daikoku, S Tranguch, IN Trofimova, DM Dinulescu, T Jacks, AY Nikitin, ... Cancer research 66 (5), 2527-2531, 2006 | 89 | 2006 |
Selectively inducing cancer cell death by intracellular enzyme‐instructed self‐assembly (EISA) of dipeptide derivatives J Li, J Shi, JE Medina, J Zhou, X Du, H Wang, C Yang, J Liu, Z Yang, ... Advanced healthcare materials 6 (15), 1601400, 2017 | 66 | 2017 |
Integrated proteomic analysis of human cancer cells and plasma from tumor bearing mice for ovarian cancer biomarker discovery SJ Pitteri, L JeBailey, VM Faça, JD Thorpe, MA Silva, RC Ireton, ... PLoS One 4 (11), e7916, 2009 | 66 | 2009 |
Therapeutically reprogrammed nutrient signalling enhances nanoparticulate albumin bound drug uptake and efficacy in KRAS-mutant cancer R Li, TSC Ng, SJ Wang, M Prytyskach, CB Rodell, H Mikula, RH Kohler, ... Nature nanotechnology 16 (7), 830-839, 2021 | 60 | 2021 |