Ilya Flyamer
Ilya Flyamer
MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, the University of Edinburgh
Verified email at
Cited by
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Single-nucleus Hi-C reveals unique chromatin reorganization at oocyte-to-zygote transition
IM Flyamer*, J Gassler*, M Imakaev*, HB Brandão, SV Ulianov, ...
Nature 544 (7648), 110-114, 2017
Active chromatin and transcription play a key role in chromosome partitioning into topologically associating domains
SV Ulianov, EE Khrameeva, AA Gavrilov, IM Flyamer, P Kos, ...
Genome research 26 (1), 70-84, 2016
A mechanism of cohesin‐dependent loop extrusion organizes zygotic genome architecture
J Gassler, HB Brandão, M Imakaev, IM Flyamer, S Ladstätter, ...
The EMBO journal 36 (24), 3600-3618, 2017
Developmentally regulated Shh expression is robust to TAD perturbations
I Williamson, L Kane, PS Devenney, IM Flyamer, E Anderson, ...
Development 146 (19), 2019
Nuclear lamina integrity is required for proper spatial organization of chromatin in Drosophila
SV Ulianov, SA Doronin, EE Khrameeva, PI Kos, AV Luzhin, SS Starikov, ...
Nature communications 10 (1), 1-11, 2019
DNA methylation directs polycomb-dependent 3D genome re-organization in naive pluripotency
K McLaughlin*, IM Flyamer*, JP Thomson, HK Mjoseng, R Shukla, ...
Cell reports 29 (7), 1974-1985. e6, 2019
342019 versatile pile-up analysis of Hi-C data
IM Flyamer, RS Illingworth, WA Bickmore
Bioinformatics 36 (10), 2980-2985, 2020
A central role for canonical PRC1 in shaping the 3D nuclear landscape
S Boyle*, IM Flyamer*, I Williamson, D Sengupta, WA Bickmore, ...
Genes & development 34 (13-14), 931-949, 2020
Activation of the alpha-globin gene expression correlates with dramatic upregulation of nearby non-globin genes and changes in local and large-scale chromatin spatial structure
SV Ulianov, AA Galitsyna, IM Flyamer, AK Golov, EE Khrameeva, ...
Epigenetics & chromatin 10 (1), 1-19, 2017
Quantitative differences in TAD border strength underly the TAD hierarchy in Drosophila chromosomes
AV Luzhin*, IM Flyamer*, EE Khrameeva, SV Ulianov, SV Razin, ...
Journal of cellular biochemistry 120 (3), 4494-4503, 2019
Bivalent promoter hypermethylation in cancer is linked to the H327me3/H3K4me3 ratio in embryonic stem cells
DS Dunican, HK Mjoseng, L Duthie, IM Flyamer, WA Bickmore, ...
BMC biology 18 (1), 1-21, 2020
C-TALE, a new cost-effective method for targeted enrichment of Hi-C/3C-seq libraries
AK Golov, SV Ulianov, AV Luzhin, EP Kalabusheva, OL Kantidze, ...
Methods 170, 48-60, 2020
Evolution of the genome 3D organization: comparison of fused and segregated globin gene clusters
AP Kovina, NV Petrova, ES Gushchanskaya, KV Dolgushin, ...
Molecular biology and evolution 34 (6), 1492-1504, 2017
Nuclear organisation and replication timing are coupled through RIF1-PP1 interaction
S Gnan, IM Flyamer, KN Klein, E Castelli, A Rapp, A Maiser, N Chen, ...
bioRxiv, 812156, 2020
Single-nucleus Hi-C of mammalian oocytes and zygotes
J Gassler, IM Flyamer, K Tachibana
Methods in cell biology 144, 389-407, 2018
MCM complexes are barriers that restrict cohesin-mediated loop extrusion
BJH Dequeker, HB Brandao, MJ Scherr, J Gassler, S Powell, I Gaspar, ...
bioRxiv, 2020
Low Level of Expression of C-Terminally Truncated Human FUS Causes Extensive Changes in the Spinal Cord Transcriptome of Asymptomatic Transgenic Mice
EA Lysikova, S Funikov, AP Rezvykh, KD Chaprov, MS Kukharsky, ...
Neurochemical research, 1-12, 2020
From bedside to bench: regulation of host factors in SARS-CoV-2 infection
SYQ Ong, IM Flyamer, WA Bickmore, SC Biddie
Experimental & Molecular Medicine, 1-12, 2021
Order and stochasticity in the folding of individual Drosophila genomes
SV Ulianov, VV Zakharova, AA Galitsyna, PI Kos, KE Polovnikov, ...
Nature Communications 12 (1), 1-17, 2021
A Mechanism of Cohesin-Dependent Loop Extrusion Organizes Mammalian Chromatin Structure in the Developing Embryo
HB Brandão, J Gassler, M Imakaev, IM Flyamer, S Ladstätter, ...
Biophysical Journal 114 (3), 255a, 2018
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