Siyuan Ding
Siyuan Ding
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TMPRSS2 and TMPRSS4 promote SARS-CoV-2 infection of human small intestinal enterocytes
R Zang, MFG Castro, BT McCune, Q Zeng, PW Rothlauf, NM Sonnek, ...
Science immunology 5 (47), eabc3582, 2020
New mitochondrial DNA synthesis enables NLRP3 inflammasome activation
Z Zhong, S Liang, E Sanchez-Lopez, F He, S Shalapour, X Lin, J Wong, ...
Nature 560 (7717), 198-203, 2018
Neutralizing antibody and soluble ACE2 inhibition of a replication-competent VSV-SARS-CoV-2 and a clinical isolate of SARS-CoV-2
JB Case, PW Rothlauf, RE Chen, Z Liu, H Zhao, AS Kim, LM Bloyet, ...
Cell host & microbe 28 (3), 475-485. e5, 2020
Nlrp9b inflammasome restricts rotavirus infection in intestinal epithelial cells
S Zhu, S Ding, P Wang, Z Wei, W Pan, NW Palm, Y Yang, H Yu, HB Li, ...
Nature 546 (7660), 667-670, 2017
Is SARS-CoV-2 also an enteric pathogen with potential fecal–oral transmission? A COVID-19 virological and clinical review
S Ding, TJ Liang
Gastroenterology 159 (1), 53-61, 2020
Dynamic expression profiling of type I and type III interferon‐stimulated hepatocytes reveals a stable hierarchy of gene expression
CR Bolen, S Ding, MD Robek, SH Kleinstein
Hepatology 59 (4), 1262-1272, 2014
Cholesterol 25-hydroxylase suppresses SARS-CoV-2 replication by blocking membrane fusion
R Zang, JB Case, E Yutuc, X Ma, S Shen, MF Gomez Castro, Z Liu, ...
Proceedings of the National Academy of Sciences 117 (50), 32105-32113, 2020
SARS-CoV-2 exacerbates proinflammatory responses in myeloid cells through C-type lectin receptors and Tweety family member 2
Q Lu, J Liu, S Zhao, MFG Castro, M Laurent-Rolle, J Dong, X Ran, ...
Immunity 54 (6), 1304-1319. e9, 2021
VP4-and VP7-specific antibodies mediate heterotypic immunity to rotavirus in humans
N Nair, N Feng, LK Blum, M Sanyal, S Ding, B Jiang, A Sen, JM Morton, ...
Science translational medicine 9 (395), eaam5434, 2017
STAG2 deficiency induces interferon responses via cGAS-STING pathway and restricts virus infection
S Ding, J Diep, N Feng, L Ren, B Li, YS Ooi, X Wang, KF Brulois, ...
Nature communications 9 (1), 1485, 2018
Long-distance interferon signaling within the brain blocks virus spread
AN van den Pol, S Ding, MD Robek
Journal of virology 88 (7), 3695-3704, 2014
Drebrin restricts rotavirus entry by inhibiting dynamin-mediated endocytosis
B Li, S Ding, N Feng, N Mooney, YS Ooi, L Ren, J Diep, MR Kelly, ...
Proceedings of the National Academy of Sciences 114 (18), E3642-E3651, 2017
Rotavirus VP3 targets MAVS for degradation to inhibit type III interferon expression in intestinal epithelial cells
S Ding, S Zhu, L Ren, N Feng, Y Song, X Ge, B Li, RA Flavell, ...
Elife 7, e39494, 2018
DDX6 represses aberrant activation of interferon-stimulated genes
JH Lumb, Q Li, LM Popov, S Ding, MT Keith, BD Merrill, HB Greenberg, ...
Cell reports 20 (4), 819-831, 2017
Comparative proteomics reveals strain-specific β-TrCP degradation via rotavirus NSP1 hijacking a host Cullin-3-Rbx1 complex
S Ding, N Mooney, B Li, MR Kelly, N Feng, AV Loktev, A Sen, JT Patton, ...
PLoS pathogens 12 (10), e1005929, 2016
Enterovirus pathogenesis requires the host methyltransferase SETD3
J Diep, YS Ooi, AW Wilkinson, CE Peters, E Foy, JR Johnson, J Zengel, ...
Nature microbiology 4 (12), 2523-2537, 2019
Epigenetic reprogramming of the type III interferon response potentiates antiviral activity and suppresses tumor growth
S Ding, W Khoury-Hanold, A Iwasaki, MD Robek
PLoS biology 12 (1), e1001758, 2014
An optimized reverse genetics system suitable for efficient recovery of simian, human, and murine-like rotaviruses
L Sánchez-Tacuba, N Feng, NJ Meade, KH Mellits, PH Jaďs, LL Yasukawa, ...
Journal of virology 94 (18), 10.1128/jvi. 01294-20, 2020
TMPRSS2 and TMPRSS4 promote SARS-CoV-2 infection of human small intestinal enterocytes. Sci Immunol 5: eabc3582
R Zang, MF Gomez Castro, BT McCune, Q Zeng, PW Rothlauf, ...
Human VP8* mAbs neutralize rotavirus selectively in human intestinal epithelial cells
N Feng, L Hu, S Ding, M Sanyal, B Zhao, B Sankaran, S Ramani, ...
The Journal of clinical investigation 129 (9), 3839-3851, 2019
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