| Single-cell transcriptomics of regulatory T cells reveals trajectories of tissue adaptation RJ Miragaia, T Gomes, A Chomka, L Jardine, A Riedel, AN Hegazy, ... Immunity 50 (2), 493-504. e7, 2019 | 425 | 2019 |
| Establishment of porcine and human expanded potential stem cells X Gao, M Nowak-Imialek, X Chen, D Chen, D Herrmann, D Ruan, ... Nature cell biology 21 (6), 687-699, 2019 | 299 | 2019 |
| Single-cell RNA-seq identifies a PD-1hi ILC progenitor and defines its development pathway Y Yu, JCH Tsang, C Wang, S Clare, J Wang, X Chen, C Brandt, L Kane, ... Nature 539 (7627), 102-106, 2016 | 284 | 2016 |
| Establishment of mouse expanded potential stem cells J Yang, DJ Ryan, W Wang, JCH Tsang, G Lan, H Masaki, X Gao, ... Nature 550 (7676), 393-397, 2017 | 261 | 2017 |
| The forkhead transcription factor FOXM1 controls cell cycle-dependent gene expression through an atypical chromatin binding mechanism X Chen, GA Müller, M Quaas, M Fischer, N Han, B Stutchbury, ... Molecular and cellular biology 33 (2), 227-236, 2013 | 228 | 2013 |
| Single-cell RNA sequencing reveals a dynamic stromal niche that supports tumor growth S Davidson, M Efremova, A Riedel, B Mahata, J Pramanik, J Huuhtanen, ... Cell reports 31 (7), 2020 | 210 | 2020 |
| Gene expression variability across cells and species shapes innate immunity T Hagai, X Chen, RJ Miragaia, R Rostom, T Gomes, N Kunowska, ... Nature 563 (7730), 197-202, 2018 | 202 | 2018 |
| Single cell RNA-seq and ATAC-seq analysis of cardiac progenitor cell transition states and lineage settlement G Jia, J Preussner, X Chen, S Guenther, X Yuan, M Yekelchyk, C Kuenne, ... Nature communications 9 (1), 4877, 2018 | 195 | 2018 |
| A rapid and robust method for single cell chromatin accessibility profiling X Chen, RJ Miragaia, KN Natarajan, SA Teichmann Nature communications 9 (1), 5345, 2018 | 186 | 2018 |
| Genome-wide CRISPR screens in T helper cells reveal pervasive crosstalk between activation and differentiation J Henriksson, X Chen, T Gomes, U Ullah, KB Meyer, R Miragaia, G Duddy, ... Cell 176 (4), 882-896. e18, 2019 | 160 | 2019 |
| From tissues to cell types and back: single-cell gene expression analysis of tissue architecture X Chen, SA Teichmann, KB Meyer Annual Review of Biomedical Data Science 1, 29-51, 2018 | 104 | 2018 |
| Genome-wide analyses reveal the IRE1a-XBP1 pathway promotes T helper cell differentiation by resolving secretory stress and accelerating proliferation J Pramanik, X Chen, G Kar, J Henriksson, T Gomes, JE Park, K Natarajan, ... Genome medicine 10, 1-19, 2018 | 79 | 2018 |
| Single-cell analysis at the threshold X Chen, JC Love, NE Navin, L Pachter, MJT Stubbington, V Svensson, ... Nature biotechnology 34 (11), 1111-1118, 2016 | 73 | 2016 |
| Tumors induce de novo steroid biosynthesis in T cells to evade immunity B Mahata, J Pramanik, L van der Weyden, K Polanski, G Kar, A Riedel, ... Nature communications 11 (1), 3588, 2020 | 67 | 2020 |
| Screen for multi-SUMO–binding proteins reveals a multi-SIM–binding mechanism for recruitment of the transcriptional regulator ZMYM2 to chromatin E Aguilar-Martinez, X Chen, A Webber, AP Mould, A Seifert, RT Hay, ... Proceedings of the National Academy of Sciences 112 (35), E4854-E4863, 2015 | 51 | 2015 |
| ISSAAC-seq enables sensitive and flexible multimodal profiling of chromatin accessibility and gene expression in single cells W Xu, W Yang, Y Zhang, Y Chen, N Hong, Q Zhang, X Wang, Y Hu, ... Nature Methods 19 (10), 1243-1249, 2022 | 49 | 2022 |
| Genome-wide binding studies reveal DNA binding specificity mechanisms and functional interplay amongst Forkhead transcription factors X Chen, Z Ji, A Webber, AD Sharrocks Nucleic acids research 44 (4), 1566-1578, 2016 | 43 | 2016 |
| Deregulation of the FOXM1 target gene network and its coregulatory partners in oesophageal adenocarcinoma EF Wiseman, X Chen, N Han, A Webber, Z Ji, AD Sharrocks, YS Ang Molecular cancer 14, 1-14, 2015 | 43 | 2015 |
| Reinvestigation of classic T cell subsets and identification of novel cell subpopulations by single-cell RNA sequencing X Wang, X Shen, S Chen, H Liu, N Hong, H Zhong, X Chen, W Jin The Journal of Immunology 208 (2), 396-406, 2022 | 41 | 2022 |
| A plate-based single-cell ATAC-seq workflow for fast and robust profiling of chromatin accessibility W Xu, Y Wen, Y Liang, Q Xu, X Wang, W Jin, X Chen Nature protocols 16 (8), 4084-4107, 2021 | 39 | 2021 |
Sarah A. TeichmannWellcome Sanger Institute & University of CambridgeVerified email at cam.ac.uk
