Clinical pharmacokinetics of docetaxel SJ Clarke, LP Rivory Clinical pharmacokinetics 36, 99-114, 1999 | 571 | 1999 |
Conversion of irinotecan (CPT-11) to its active metabolite, 7-ethyl-10-hydroxycamptothecin (SN-38), by human liver carboxylesterase LP Rivory, MR Bowles, J Robert, SM Pond Biochemical pharmacology 52 (7), 1103-1111, 1996 | 303 | 1996 |
Inflammatory response: an unrecognised source of variability in the pharmacokinetics and pharmacodynamics of cancer chemotherapy KA Slaviero, SJ Clarke, LP Rivory The lancet oncology 4 (4), 224-232, 2003 | 291 | 2003 |
Hepatic cytochrome P450 3A drug metabolism is reduced in cancer patients who have an acute-phase response LP Rivory, KA Slaviero, SJ Clarke British journal of cancer 87 (3), 277-280, 2002 | 248 | 2002 |
Metabolism of irinotecan (CPT-11) by human hepatic microsomes: participation of cytochrome P-450 3A and drug interactions MC Haaz, L Rivory, C Riche, L Vernillet, J Robert Cancer research 58 (3), 468-472, 1998 | 201 | 1998 |
The hepatic sinusoid in aging and cirrhosis: effects on hepatic substrate disposition and drug clearance DG Le Couteur, R Fraser, S Kilmer, LP Rivory, AJ McLean Clinical pharmacokinetics 44, 187-200, 2005 | 191 | 2005 |
Pharmacokinetic interrelationships of irinotecan (CPT-11) and its three major plasma metabolites in patients enrolled in phase I/II trials. LP Rivory, MC Haaz, P Canal, F Lokiec, JP Armand, J Robert Clinical cancer research: an official journal of the American Association …, 1997 | 177 | 1997 |
Imatinib Disposition and ABCB1 (MDR1, P‐Glycoprotein) Genotype H Gurney, M Wong, RL Balleine, LP Rivory, AJ McLachlan, JM Hoskins, ... Clinical Pharmacology & Therapeutics 82 (1), 33-40, 2007 | 175 | 2007 |
Identification and properties of a major plasma metabolite of irinotecan (CPT-11) isolated from the plasma of patients LP Rivory, JF Riou, MC Haaz, S Sable, M Vuilhorgne, A Commerçon, ... Cancer Research 56 (16), 3689-3694, 1996 | 164 | 1996 |
Baseline nutritional assessment in advanced cancer patients receiving palliative chemotherapy KA Slaviero, JA Read, SJ Clarke, LP Rivory Nutrition and cancer 46 (2), 148-157, 2003 | 161 | 2003 |
Identification and kinetics of a β-glucuronide metabolite of SN-38 in human plasma after administration of the camptothecin derivative irinotecan LP Rivory, J Robert Cancer chemotherapy and pharmacology 36, 176-179, 1995 | 152 | 1995 |
Factors affecting cytochrome P-450 3A activity in cancer patients SD Baker, RHN Van Schaik, LP Rivory, AJ Ten Tije, K Dinh, ... Clinical cancer research 10 (24), 8341-8350, 2004 | 150 | 2004 |
Kinetics of the in Vivo Interconversion of the Carboxylate and Lactone Forms of Irinotecan (CPT-11) and of Its Metabolite SN-38 in Patients LP Rivory, E Chatelut, P Canal, A Mathieu-Boué, J Robert Cancer research 54 (24), 6330-6333, 1994 | 148 | 1994 |
Identification of a new metabolite of CPT-11 (irinotecan): pharmacological properties and activation to SN-38 HM Dodds, MC Haaz, JF Riou, J Robert, LP Rivory Journal of Pharmacology and Experimental Therapeutics 286 (1), 578-583, 1998 | 137 | 1998 |
Thymidylate synthase and methylenetetrahydrofolate reductase gene polymorphisms and toxicity to capecitabine in advanced colorectal cancer patients R Sharma, JM Hoskins, LP Rivory, M Zucknick, R London, C Liddle, ... Clinical cancer research 14 (3), 817-825, 2008 | 135 | 2008 |
Reversed-phase high-performance liquid chromatographic method for the simultaneous quantitation of the carboxylate and lactone forms of the camptothecin derivative irinotecan … LP Rivory, J Robert Journal of Chromatography B: Biomedical Sciences and Applications 661 (1 …, 1994 | 127 | 1994 |
Molecular, cellular, and clinical aspects of the pharmacology of 20 (S) camptothecin and its derivatives LP Rivory, J Robert Pharmacology & therapeutics 68 (2), 269-296, 1995 | 111 | 1995 |
Transcriptional Repression of Hepatic Cytochrome P450 3A4 Gene in the Presence of Cancer KA Charles, LP Rivory, SL Brown, C Liddle, SJ Clarke, GR Robertson Clinical cancer research 12 (24), 7492-7497, 2006 | 87 | 2006 |
The transformation of irinotecan (CPT-11) to its active metabolite SN-38 by human liver microsomes Differential hydrolysis for the lactone and carboxylate forms: Differential … MC Haaz, LP Rivory, C Riché, J Robert Naunyn-Schmiedeberg's archives of pharmacology 356, 257-262, 1997 | 86 | 1997 |
Frequency of cytochrome P 450 3A4 variant genotype in transplant population and lack of association with cyclosporin clearance LP Rivory, H Qin, SJ Clarke, J Eris, G Duggin, E Ray, RJ Trent, JF Bishop European journal of clinical pharmacology 56, 395-398, 2000 | 82 | 2000 |