The T-box transcription factor Eomesodermin acts upstream of Mesp1 to specify cardiac mesoderm during mouse gastrulation I Costello, IM Pimeisl, S Dräger, EK Bikoff, EJ Robertson, SJ Arnold Nature cell biology 13 (9), 1084-1091, 2011 | 285 | 2011 |
NuRD suppresses pluripotency gene expression to promote transcriptional heterogeneity and lineage commitment N Reynolds, P Latos, A Hynes-Allen, R Loos, D Leaford, ... Cell stem cell 10 (5), 583-594, 2012 | 269 | 2012 |
Keeping things quiet: roles of NuRD and Sin3 co-repressor complexes during mammalian development P McDonel, I Costello, B Hendrich The international journal of biochemistry & cell biology 41 (1), 108-116, 2009 | 145 | 2009 |
Lhx1 functions together with Otx2, Foxa2, and Ldb1 to govern anterior mesendoderm, node, and midline development I Costello, S Nowotschin, X Sun, AW Mould, AK Hadjantonakis, EK Bikoff, ... Genes & development 29 (20), 2108-2122, 2015 | 100 | 2015 |
The T-box transcription factor Eomesodermin is essential for AVE induction in the mouse embryo S Nowotschin, I Costello, A Piliszek, GS Kwon, C Mao, WH Klein, ... Genes & development 27 (9), 997-1002, 2013 | 74 | 2013 |
Constraint of gene expression by the chromatin remodelling protein CHD4 facilitates lineage specification A O'Shaughnessy-Kirwan, J Signolet, I Costello, S Gharbi, B Hendrich Development 142 (15), 2586-2597, 2015 | 67 | 2015 |
Smad4-dependent pathways control basement membrane deposition and endodermal cell migration at early stages of mouse development I Costello, CA Biondi, JM Taylor, EK Bikoff, EJ Robertson BMC developmental biology 9, 1-16, 2009 | 59 | 2009 |
The fibronectin leucine-rich repeat transmembrane protein Flrt2 is required in the epicardium to promote heart morphogenesis PS Müller, R Schulz, S Maretto, I Costello, S Srinivas, E Bikoff, ... Development 138 (7), 1297-1308, 2011 | 58 | 2011 |
Genetic dissection of Nodal and Bmp signalling requirements during primordial germ cell development in mouse AD Senft, EK Bikoff, EJ Robertson, I Costello Nature communications 10 (1), 1089, 2019 | 47 | 2019 |
Functional characterisation of cis-regulatory elements governing dynamic Eomes expression in the early mouse embryo CS Simon, DJ Downes, ME Gosden, J Telenius, DR Higgs, JR Hughes, ... Development 144 (7), 1249-1260, 2017 | 43 | 2017 |
Combinatorial Smad2/3 activities downstream of nodal signaling maintain embryonic/extra-embryonic cell identities during lineage priming AD Senft, I Costello, HW King, AW Mould, EK Bikoff, EJ Robertson Cell Reports 24 (8), 1977-1985. e7, 2018 | 36 | 2018 |
The PR/SET domain zinc finger protein Prdm4 regulates gene expression in embryonic stem cells but plays a nonessential role in the developing mouse embryo D Bogani, MAJ Morgan, AC Nelson, I Costello, JF McGouran, BM Kessler, ... Molecular and cellular biology 33 (19), 3936-3950, 2013 | 35 | 2013 |
Dra ̈ ger, S., Bikoff, EK, Robertson, EJ and Arnold, SJ(2011). The T-box transcription factor Eomesodermin acts upstream of Mesp1 to specify cardiac mesoderm during mouse … I Costello, IM Pimeisl Nat. Cell Biol 13, 1084-1091, 0 | 27 | |
The transcriptional repressor Blimp1/PRDM1 regulates the maternal decidual response in mice M Goolam, ME Xypolita, I Costello, JP Lydon, FJ DeMayo, EK Bikoff, ... Nature Communications 11 (1), 2782, 2020 | 20 | 2020 |
CytoCensus, mapping cell identity and division in tissues and organs using machine learning M Hailstone, D Waithe, TJ Samuels, L Yang, I Costello, Y Arava, ... Elife 9, e51085, 2020 | 20 | 2020 |
The T-box transcription factor Eomesodermin governs haemogenic competence of yolk sac mesodermal progenitors LTG Harland, CS Simon, AD Senft, I Costello, L Greder, ... Nature cell biology 23 (1), 61-74, 2021 | 10 | 2021 |
A degron-based approach to manipulate Eomes functions in the context of the developing mouse embryo AM Bisia, I Costello, ME Xypolita, LTG Harland, PJ Kurbel, EK Bikoff, ... Proceedings of the National Academy of Sciences 120 (44), e2311946120, 2023 | 1 | 2023 |
Genetic dissection of Nodal and Bmp signalling requirements during primordial germ cell development AD Senft, EK Bikoff, EJ Robertson, I Costello bioRxiv, 464776, 2018 | 1 | 2018 |
Cytocensus: mapping cell identity and division in tissues and organs using machine learning M Hailstone, D Waithe, TJ Samuels, L Yang, I Costello, Y Arava, ... bioRxiv, 137406, 2017 | 1 | 2017 |
The T-box transcription factor Eomesodermin governs haemogenic competence of yolk sac mesodermal progenitors (vol 23, pg 61, 2021) LTG Harland, CS Simon, AD Senft, I Costello, L Greder, ... NATURE CELL BIOLOGY 23 (3), 293-293, 2021 | | 2021 |