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Dian Yang
Dian Yang
Columbia University
Verified email at stanford.edu
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Year
Comprehensive genomic profiles of small cell lung cancer
J George, JS Lim, SJ Jang, Y Cun, L Ozretić, G Kong, F Leenders, X Lu, ...
Nature 524 (7563), 47-53, 2015
19162015
CD47-blocking immunotherapies stimulate macrophage-mediated destruction of small-cell lung cancer
K Weiskopf, NS Jahchan, PJ Schnorr, S Cristea, AM Ring, RL Maute, ...
The Journal of clinical investigation 126 (7), 2610-2620, 2016
3822016
Intratumoural heterogeneity generated by Notch signalling promotes small-cell lung cancer
JS Lim, A Ibaseta, MM Fischer, B Cancilla, G O’Young, S Cristea, VC Luca, ...
Nature 545 (7654), 360-364, 2017
3672017
A drug repositioning approach identifies tricyclic antidepressants as inhibitors of small cell lung cancer and other neuroendocrine tumors
NS Jahchan, JT Dudley, PK Mazur, N Flores, D Yang, A Palmerton, ...
Cancer discovery 3 (12), 1364-1377, 2013
3662013
Nfib Promotes Metastasis through a Widespread Increase in Chromatin Accessibility
SK Denny*, D Yang*, CH Chuang, JJ Brady, JS Lim, BM Grüner, ...
Cell, 2016
3302016
Molecular recording of mammalian embryogenesis
MM Chan, ZD Smith, S Grosswendt, H Kretzmer, TM Norman, B Adamson, ...
Nature 570 (7759), 77-82, 2019
2792019
Pancreatic cancer modeling using retrograde viral vector delivery and in vivo CRISPR/Cas9-mediated somatic genome editing
SH Chiou, IP Winters, J Wang, S Naranjo, C Dudgeon, FB Tamburini, ...
Genes & development 29 (14), 1576-1585, 2015
2642015
Mapping transcriptomic vector fields of single cells
X Qiu, Y Zhang, JD Martin-Rufino, C Weng, S Hosseinzadeh, D Yang, ...
Cell 185 (4), 690-711. e45, 2022
1762022
Molecular definition of a metastatic lung cancer state reveals a targetable CD109–Janus kinase–Stat axis
CH Chuang, PG Greenside, ZN Rogers, JJ Brady, D Yang, RK Ma, ...
Nature medicine 23 (3), 291-300, 2017
1462017
Efficient C• G-to-G• C base editors developed using CRISPRi screens, target-library analysis, and machine learning
LW Koblan, M Arbab, MW Shen, JA Hussmann, AV Anzalone, JL Doman, ...
Nature biotechnology 39 (11), 1414-1425, 2021
1342021
Intertumoral heterogeneity in SCLC is influenced by the cell type of origin
D Yang, SK Denny, PG Greenside, AC Chaikovsky, JJ Brady, Y Ouadah, ...
Cancer discovery 8 (10), 1316-1331, 2018
1212018
Lineage tracing reveals the phylodynamics, plasticity, and paths of tumor evolution
D Yang, MG Jones, S Naranjo, WM Rideout III, KHJ Min, R Ho, W Wu, ...
Cell 185 (11), 1905-1923. e25, 2022
1002022
Mapping the genetic landscape of DNA double-strand break repair
JA Hussmann, J Ling, P Ravisankar, J Yan, A Cirincione, A Xu, ...
Cell 184 (22), 5653-5669. e25, 2021
982021
Identification and targeting of long-term tumor-propagating cells in small cell lung cancer
N Jahchan, J Lim, B Bola, D Yang, J George, M Peifer, F Blackhall, C Dive, ...
Cancer discovery 11 (2), S12, 2016
862016
An in vivo multiplexed small-molecule screening platform
BM Grüner*, CJ Schulze*, D Yang, D Ogasawara, MM Dix, ZN Rogers, ...
Nature Methods, 2016
612016
BLIMP1 induces transient metastatic heterogeneity in pancreatic cancer
SH Chiou, VI Risca, GX Wang, D Yang, BM Grüner, AS Kathiria, RK Ma, ...
Cancer discovery 7 (10), 1184-1199, 2017
562017
Obligate progression precedes lung adenocarcinoma dissemination
DR Caswell*, CH Chuang*, D Yang, SH Chiou, S Cheemalavagu, ...
Cancer discovery 4 (7), 781-789, 2014
552014
Post-transcriptional homeostasis and regulation of MCM2–7 in mammalian cells
CH Chuang, D Yang, G Bai, A Freeland, SC Pruitt, JC Schimenti
Nucleic acids research 40 (11), 4914-4924, 2012
442012
Axon-like protrusions promote small cell lung cancer migration and metastasis
D Yang, F Qu, H Cai, CH Chuang, JS Lim, N Jahchan, BM Grüner, ...
Elife 8, e50616, 2019
412019
Altered mitochondria functionality defines a metastatic cell state in lung cancer and creates an exploitable vulnerability
CH Chuang, M Dorsch, P Dujardin, S Silas, K Ueffing, JM Hölken, D Yang, ...
Cancer research 81 (3), 567-579, 2021
292021
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