| CAVER 3.0: a tool for the analysis of transport pathways in dynamic protein structures E Chovancova, A Pavelka, P Benes, O Strnad, J Brezovsky, B Kozlikova, ... PLoS Comput Biol 8 (10), e1002708, 2012 | 714 | 2012 |
| PredictSNP: robust and accurate consensus classifier for prediction of disease-related mutations J Bendl, J Stourac, O Salanda, A Pavelka, ED Wieben, J Zendulka, ... PLoS Comput Biol 10 (1), e1003440, 2014 | 393 | 2014 |
| Computational tools for designing and engineering enzymes J Damborsky, J Brezovsky Current opinion in chemical biology 19, 8-16, 2014 | 170 | 2014 |
| Gates of enzymes A Gora, J Brezovsky, J Damborsky Chemical reviews 113 (8), 5871-5923, 2013 | 148 | 2013 |
| CAVER Analyst 1.0: graphic tool for interactive visualization and analysis of tunnels and channels in protein structures B Kozlikova, E Sebestova, V Sustr, J Brezovsky, O Strnad, L Daniel, ... Bioinformatics 30 (18), 2684-2685, 2014 | 138 | 2014 |
| Computational tools for designing and engineering biocatalysts J Damborsky, J Brezovsky Current opinion in chemical biology 13 (1), 26-34, 2009 | 130 | 2009 |
| Enantioselectivity of haloalkane dehalogenases and its modulation by surface loop engineering Z Prokop*, Y Sato*, J Brezovsky*, T Mozga, R Chaloupkova, ... Angewandte Chemie International Edition 49 (35), 6111-6115, 2010 | 118 | 2010 |
| Engineering enzyme stability and resistance to an organic cosolvent by modification of residues in the access tunnel T Koudelakova, R Chaloupkova, J Brezovsky, Z Prokop, E Sebestova, ... Angewandte Chemie 125 (7), 2013-2017, 2013 | 117 | 2013 |
| Substrate specificity of haloalkane dehalogenases T Koudelakova, E Chovancova, J Brezovsky, M Monincova, A Fortova, ... Biochemical Journal 435 (2), 345-354, 2011 | 112 | 2011 |
| Tools and data services registry: a community effort to document bioinformatics resources J Ison, K Rapacki, H Ménager, M Kalaš, E Rydza, P Chmura, C Anthon, ... Nucleic acids research 44 (D1), D38-D47, 2016 | 110 | 2016 |
| PredictSNP2: a unified platform for accurately evaluating SNP effects by exploiting the different characteristics of variants in distinct genomic regions J Bendl, M Musil, J Štourač, J Zendulka, J Damborský*, J Brezovský* PLoS computational biology 12 (5), e1004962, 2016 | 93 | 2016 |
| FireProt: energy-and evolution-based computational design of thermostable multiple-point mutants D Bednar, K Beerens, E Sebestova, J Bendl, S Khare, R Chaloupkova, ... PLoS Comput Biol 11 (11), e1004556, 2015 | 80 | 2015 |
| CAVER Analyst 2.0: analysis and visualization of channels and tunnels in protein structures and molecular dynamics trajectories A Jurcik, D Bednar, J Byska, SM Marques, K Furmanova, L Daniel, ... Bioinformatics 34 (20), 3586-3588, 2018 | 78 | 2018 |
| Software tools for identification, visualization and analysis of protein tunnels and channels J Brezovsky, E Chovancova, A Gora, A Pavelka, L Biedermannova, ... Biotechnology advances 31 (1), 38-49, 2013 | 77 | 2013 |
| HotSpot Wizard 2.0: automated design of site-specific mutations and smart libraries in protein engineering J Bendl, J Stourac, E Sebestova, O Vavra, M Musil, J Brezovsky*, ... Nucleic acids research 44 (W1), W479-W487, 2016 | 69 | 2016 |
| CAVER: algorithms for analyzing dynamics of tunnels in macromolecules A Pavelka, E Sebestova, B Kozlikova, J Brezovsky, J Sochor, ... IEEE/ACM transactions on computational biology and bioinformatics 13 (3 …, 2015 | 66 | 2015 |
| Dynamics and hydration explain failed functional transformation in dehalogenase design J Sykora*, J Brezovsky*, T Koudelakova*, M Lahoda, A Fortova, ... Nature chemical biology 10 (6), 428-430, 2014 | 50 | 2014 |
| Engineering a de novo transport tunnel J Brezovsky*, P Babkova*, O Degtjarik, A Fortova, A Gora, I Iermak, ... ACS Catalysis 6 (11), 7597-7610, 2016 | 48 | 2016 |
| Nanosecond time-dependent stokes shift at the tunnel mouth of haloalkane dehalogenases A Jesenská, J Sykora, A Olzynska, J Brezovsky, Z Zdrahal, J Damborsky, ... Journal of the American Chemical Society 131 (2), 494-501, 2009 | 43 | 2009 |
| Engineering of protein tunnels: Keyhole-lock-key model for catalysis by the enzymes with buried active sites Z Prokop, A Gora, J Brezovsky, R Chaloupkova, V Stepankova, ... Protein engineering handbook 3, 421-464, 2012 | 42 | 2012 |
Jiri DamborskyMasaryk UniversityVerified email at chemi.muni.cz
