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Sacha Howell
Sacha Howell
senior lecturer, Manchester University
Verified email at nhs.net
Title
Cited by
Cited by
Year
Regulation of breast cancer stem cell activity by signaling through the Notch4 receptor
H Harrison, G Farnie, SJ Howell, RE Rock, S Stylianou, KR Brennan, ...
Cancer research 70 (2), 709-718, 2010
6532010
Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer
SA Eccles, EO Aboagye, S Ali, AS Anderson, J Armes, F Berditchevski, ...
Breast Cancer Research 15, 1-37, 2013
5032013
Recent advances reveal IL-8 signaling as a potential key to targeting breast cancer stem cells
JK Singh, BM Simões, SJ Howell, G Farnie, RB Clarke
Breast Cancer Research 15, 1-9, 2013
2802013
Origins of breast cancer subtypes and therapeutic implications
AH Sims, A Howell, SJ Howell, RB Clarke
Nature Clinical Practice Oncology 4 (9), 516-525, 2007
2632007
Targeting CXCR1/2 significantly reduces breast cancer stem cell activity and increases the efficacy of inhibiting HER2 via HER2-dependent and-independent mechanisms
JK Singh, G Farnie, NJ Bundred, BM Simões, A Shergill, G Landberg, ...
Clinical cancer research 19 (3), 643-656, 2013
2422013
Detection of PIK3CA mutations in circulating free DNA in patients with breast cancer
RE Board, AM Wardley, JM Dixon, AC Armstrong, S Howell, L Renshaw, ...
Breast cancer research and treatment 120, 461-467, 2010
2352010
The use of selective estrogen receptor modulators and selective estrogen receptor down-regulators in breast cancer
SJ Howell, SRD Johnston, A Howell
Best practice & research Clinical endocrinology & metabolism 18 (1), 47-66, 2004
2332004
Fulvestrant plus capivasertib versus placebo after relapse or progression on an aromatase inhibitor in metastatic, oestrogen receptor-positive breast cancer (FAKTION): a …
RH Jones, A Casbard, M Carucci, C Cox, R Butler, F Alchami, TA Madden, ...
The Lancet Oncology 21 (3), 345-357, 2020
1892020
Anti-estrogen resistance in human breast tumors is driven by JAG1-NOTCH4-dependent cancer stem cell activity
BM Simoes, CS O’Brien, R Eyre, A Silva, L Yu, A Sarmiento-Castro, ...
Cell reports 12 (12), 1968-1977, 2015
1882015
Impaired tamoxifen metabolism reduces survival in familial breast cancer patients
WG Newman, KD Hadfield, A Latif, SA Roberts, A Shenton, C McHague, ...
Clinical Cancer Research 14 (18), 5913-5918, 2008
1412008
Breast cancer: current and future endocrine therapies
C Palmieri, DK Patten, A Januszewski, G Zucchini, SJ Howell
Molecular and cellular endocrinology 382 (1), 695-723, 2014
1372014
Tositumomab and iodine I 131 tositumomab for recurrent indolent and transformed B-cell non-Hodgkin’s lymphoma
AJ Davies, AZS Rohatiner, S Howell, KE Britton, SE Owens, IN Micallef, ...
Journal of clinical oncology 22 (8), 1469-1479, 2004
1352004
The value of bone marrow examination in the staging of Hodgkin's lymphoma: a review of 955 cases seen in a regional cancer centre
SJ Howell, M Grey, J Chang, GR Morgenstern, RA Cowan, DP Deakin, ...
British journal of haematology 119 (2), 408-411, 2002
1332002
HER2-targeted therapy in breast cancer: a systematic review of neoadjuvant trials
S Dent, B Oyan, A Honig, M Mano, S Howell
Cancer treatment reviews 39 (6), 622-631, 2013
1272013
Microenvironmental IL1β promotes breast cancer metastatic colonisation in the bone via activation of Wnt signalling
R Eyre, DG Alférez, A Santiago-Gómez, K Spence, JC McConnell, C Hart, ...
Nature communications 10 (1), 5016, 2019
1152019
Capivasertib in hormone receptor–positive advanced breast cancer
NC Turner, M Oliveira, SJ Howell, F Dalenc, J Cortes, HL Gomez Moreno, ...
New England Journal of Medicine 388 (22), 2058-2070, 2023
1122023
Doxycycline down-regulates DNA-PK and radiosensitizes tumor initiating cells: Implications for more effective radiation therapy
R Lamb, M Fiorillo, A Chadwick, B Ozsvari, KJ Reeves, DL Smith, ...
Oncotarget 6 (16), 14005, 2015
1122015
Oestrogen increases the activity of oestrogen receptor negative breast cancer stem cells through paracrine EGFR and Notch signalling
H Harrison, BM Simões, L Rogerson, SJ Howell, G Landberg, RB Clarke
Breast Cancer Research 15, 1-12, 2013
1072013
Facilitating reproductive choices: the impact of health services on the experiences of young women with breast cancer
RJ Lee, A Wakefield, S Foy, SJ Howell, AM Wardley, AC Armstrong
Psycho‐oncology 20 (10), 1044-1052, 2011
932011
Resistance to endocrine therapy: are breast cancer stem cells the culprits?
CS O’Brien, SJ Howell, G Farnie, RB Clarke
Journal of mammary gland biology and neoplasia 14, 45-54, 2009
772009
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